Hypoglycaemic effects of Salsola kali, S. soda, andS. oppositifolia (Chenopodiaceae) aerial parts were examinedusing in vitro assay based on the inhibition ofa-amylase. The S. kali ethyl acetate fraction was themost active with a IC50 value 0.022 mg/ml. Throughbioassay-guided fractionation processes two flavonolglycosides, isorhamnetin-3-O-glucoside and isorhamnetin-3-O-rutinoside, were isolated by silica gel columnchromatography and characterized by spectroscopicmethods. Isorhamnetin-3-O-rutinoside showed an interestingactivity (IC50 0.129 mM).
Inhibitory effects on the digestive enzyme alpha-amylase of three Salsola species (Chenopodiaceae) in vitro
TUNDIS, ROSA;LOIZZO, Monica Rosa;STATTI, Giancarlo;
2007-01-01
Abstract
Hypoglycaemic effects of Salsola kali, S. soda, andS. oppositifolia (Chenopodiaceae) aerial parts were examinedusing in vitro assay based on the inhibition ofa-amylase. The S. kali ethyl acetate fraction was themost active with a IC50 value 0.022 mg/ml. Throughbioassay-guided fractionation processes two flavonolglycosides, isorhamnetin-3-O-glucoside and isorhamnetin-3-O-rutinoside, were isolated by silica gel columnchromatography and characterized by spectroscopicmethods. Isorhamnetin-3-O-rutinoside showed an interestingactivity (IC50 0.129 mM).File in questo prodotto:
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