Diagnostic oriented discrimination of different Shiga toxins via PCA-assisted SERS-based plasmonic metasurface

: Plasmonic biosensors are powerful platforms for detecting various types of analytes. Specifically, surface-enhanced Raman spectroscopy (SERS) can enable label-free and selective detection. Shiga toxin-producing Escherichia coli (STEC) represents zoonotic pathogens that cause severe diseases, such as hemolytic uremic syndrome (HUS), the most important cause of acute renal failure in children. To date, there are no effective therapies for STEC infection, and the available diagnostic methods a...

L’AIDS/HIV tra emergenza sanitaria, diritti e integrazione europea: l’origine del primo piano comunitario (1983-1991)

Chalcogen atom effect on the intersystem crossing kinetic constant of oxygen‐ and sulfur disubstituted heteroporphyrins

The modulation of the photophysical properties of di-substituted porphyrin rings upon the oxygen and sulfur-for-nitrogen replacement has been investigated at density functional theory (DFT) and its time-dependent formulation (TDDFT). The considered properties range from structural behaviors and excitation energies to spin-orbit coupling (SOC) and nonradiative intersystem kinetic constants. Results show that the SOC strongly increase upon chalcogen substitution and, accordingly, the computed n...

A “Talking” between Gold Nanoparticle and a Luminescent Iridium(III) Complex: A Study of the Effect Due to the Interaction between Plasmon Resonance and a Fluorophore

This paper explores a novel synthesis and characterization of silica-coated gold nanorods (AuNRs) embedding a highly emissive cyclometalated iridium(III) complex, denoted as Ir1. We investigate the optical properties and the interplay between the metal compound and gold plasmon, observing how the emission of Ir1 incorporated into the nanoparticles shows two emission bands, one in the blue and the other in the green-orange range of the visible spectrum. To obtain a clearer picture of what we w...