We developed a testing platform based on non-contact optical coherence techniques to investigate the relationship between in-vivo optic nerve head (ONH) response to intraocular pressure (IOP) and ex-vivo quantification of the corneoscleral biomechanics. One eye of a brain-dead organ donor (BDD) was imaged by Optical Coherence Tomography (OCT) to acquire the in-vivo IOP-dependent deformations of the ONH. Following organ harvesting the eye was enucleated and dissected in two hemispheres. Electronic Speckle Pattern Interferometry (ESPI) quantified the response to IOP of the posterior and anterior globes. This testing platform will investigate the relationship between corneoscleral and ONH biomechanics.
Ocular connective tissue biomechanics assessment by means of non-contact optical techniques
Fazio MA;Bianco G;BRUNO, LUIGI;
2017-01-01
Abstract
We developed a testing platform based on non-contact optical coherence techniques to investigate the relationship between in-vivo optic nerve head (ONH) response to intraocular pressure (IOP) and ex-vivo quantification of the corneoscleral biomechanics. One eye of a brain-dead organ donor (BDD) was imaged by Optical Coherence Tomography (OCT) to acquire the in-vivo IOP-dependent deformations of the ONH. Following organ harvesting the eye was enucleated and dissected in two hemispheres. Electronic Speckle Pattern Interferometry (ESPI) quantified the response to IOP of the posterior and anterior globes. This testing platform will investigate the relationship between corneoscleral and ONH biomechanics.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
