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The genus Globularia, recently included in Plantaginaceae on molecular systematics grounds, has its centre of distribution in the Mediterranean region and southern Europe with a considerable number of locally endemic species in the Cape Verde and Canary Islands, Atlas, Baleares, Italy, Greece and Turkey. Some members of this genus are well known for their biological properties. Globularia alypum L. is used for a variety of purposes such as hypoglycaemic agent, laxative, cholagogue, stomachic, purgative, sudorific and also in the treatment of cardio-vascular and renal diseases. G. arabica Jaub. & Spach is used in Jordan traditional medicine. Both Globularia species are also known for their antimicrobial and antitumorigenic activities. Globularia trichosantha Fisch. & C.A. Mey. is utilized for the treatment of haemorrhoids. The Balkan-Apennine Globularia meridionalis (Podp.) O. Schwarz is one of the eight species growing in Italy, together with: G. alypum, Globularia bisnagarica L., Globularia cordifolia L., Globularia incanescens Viv., Globularia neapolitana O. Schwarz, Globularia nudicaulis L. and Globularia repens Lam. Aerial and underground parts of G. meridionalis were collected in Pollino Massif, Calabria (Italy). Voucher specimen has been retained at the Herbarium of University of Calabria (CLU) under the reference no 12492.

Iridoid and bisiridoid glycosides from Globularia meridionalis (Podp.) O. Schwarz aerial and underground parts / Tundis, Rosa; Peruzzi, L; Colica, C; Menichini, F.. - In: BIOCHEMICAL SYSTEMATICS AND ECOLOGY. - ISSN 0305-1978. - 40(2012), pp. 71-74.

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