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EnglishThe title compounds have been obtained by 1,3-dipolar cycloadditions of methylene nitromes, prepared in situ from suitably protected hydroxylamines, to 1-N-vinyl-thymine. The 4'-aza-2',3'-dideoxyerythrofuranoside(4), an analogue of 2',3'-dideoxythymidine, might exhibit antiviral activity.
The title compounds have been obtained by 1,3-dipolar cycloadditions of methylene nitromes, prepared in situ from suitably protected hydroxylamines, to 1-N-vinyl-thymine. The 4'-aza-2',3'-dideoxyerythrofuranoside(4), an analogue of 2',3'-dideoxythymidine, might exhibit antiviral activity.
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| Titolo: | Synthesis of 4'-aza analogues of 2',3'-dideoxythymidine by 1,3-dipolar cycloadditions of nitrones to 1-N-vinyl-thymine |
| Autori: | |
| Data di pubblicazione: | 1996 |
| Rivista: | |
| Abstract: | The title compounds have been obtained by 1,3-dipolar cycloadditions of methylene nitromes, prepared in situ from suitably protected hydroxylamines, to 1-N-vinyl-thymine. The 4'-aza-2',3'-dideoxyerythrofuranoside(4), an analogue of 2',3'-dideoxythymidine, might exhibit antiviral activity. |
| Handle: | http://hdl.handle.net/20.500.11770/126018 |
| Appare nelle tipologie: | 1.1 Articolo in rivista |
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http://hdl.handle.net/20.500.11770/126018
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