In order to support scientifically the traditional use of Salsola species in the treatment of hypertension, this study was designed to evaluate the hypotensive properties of Salsola oppositifolia, S. soda and S. tragus. In vitro bio-assay based on the measured enzymatic cleavage of the chromophore–fluorophore-labelled substrate dansyltriglycine into dansylglycine and diglycine by angiotensin converting enzyme (ACE) was performed. EtOAc extracts of S. oppositifolia and S. soda exhibited an interesting activity with an IC50 of 181.04 and 284.27 microg/mL, respectively.

In order to support scientifically the traditional use of Salsola species in the treatment of hypertension, this study was designed to evaluate the hypotensive properties of Salsola oppositifolia, S. soda and S. tragus. In vitro bio-assay based on the measured enzymatic cleavage of the chromophore–fluorophore-labelled substrate dansyltriglycine into dansylglycine and diglycine by angiotensin converting enzyme (ACE) was performed. EtOAc extracts of S. oppositifolia and S. soda exhibited an interesting activity with an IC50 of 181.04 and 284.27 mg/mL, respectively.

In vitro Angiotensin Converting Enzyme (ACE) inhibiting activity of Salsola oppositifolia Desf., Salsola soda L. and Salsola tragus L

LOIZZO, Monica Rosa;TUNDIS, ROSA;PASSALACQUA N;
2007

Abstract

In order to support scientifically the traditional use of Salsola species in the treatment of hypertension, this study was designed to evaluate the hypotensive properties of Salsola oppositifolia, S. soda and S. tragus. In vitro bio-assay based on the measured enzymatic cleavage of the chromophore–fluorophore-labelled substrate dansyltriglycine into dansylglycine and diglycine by angiotensin converting enzyme (ACE) was performed. EtOAc extracts of S. oppositifolia and S. soda exhibited an interesting activity with an IC50 of 181.04 and 284.27 mg/mL, respectively.
In order to support scientifically the traditional use of Salsola species in the treatment of hypertension, this study was designed to evaluate the hypotensive properties of Salsola oppositifolia, S. soda and S. tragus. In vitro bio-assay based on the measured enzymatic cleavage of the chromophore–fluorophore-labelled substrate dansyltriglycine into dansylglycine and diglycine by angiotensin converting enzyme (ACE) was performed. EtOAc extracts of S. oppositifolia and S. soda exhibited an interesting activity with an IC50 of 181.04 and 284.27 microg/mL, respectively.
Salsola species; ACE inhibition
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11770/129638
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