In order to support scientifically the traditional use of Salsola species in the treatment ofhypertension, this study was designed to evaluate the hypotensive properties of Salsolaoppositifolia, S. soda and S. tragus. In vitro bio-assay based on the measured enzymatic cleavageof the chromophore–fluorophore-labelled substrate dansyltriglycine into dansylglycine anddiglycine by angiotensin converting enzyme (ACE) was performed. EtOAc extracts of S.oppositifolia and S. soda exhibited an interesting activity with an IC50 of 181.04 and284.27 microg/mL, respectively.
In order to support scientifically the traditional use of Salsola species in the treatment ofhypertension, this study was designed to evaluate the hypotensive properties of Salsolaoppositifolia, S. soda and S. tragus. In vitro bio-assay based on the measured enzymatic cleavageof the chromophore–fluorophore-labelled substrate dansyltriglycine into dansylglycine anddiglycine by angiotensin converting enzyme (ACE) was performed. EtOAc extracts of S.oppositifolia and S. soda exhibited an interesting activity with an IC50 of 181.04 and284.27 mg/mL, respectively.
In vitro angiotensin converting enzyme inhibiting activity of Salsola oppositifolia Desf., Salsola soda L. and Salsola tragus L.
Loizzo M. R.;Tundis R.;Statti G. A.;Passalacqua N. G.;
2007-01-01
Abstract
In order to support scientifically the traditional use of Salsola species in the treatment ofhypertension, this study was designed to evaluate the hypotensive properties of Salsolaoppositifolia, S. soda and S. tragus. In vitro bio-assay based on the measured enzymatic cleavageof the chromophore–fluorophore-labelled substrate dansyltriglycine into dansylglycine anddiglycine by angiotensin converting enzyme (ACE) was performed. EtOAc extracts of S.oppositifolia and S. soda exhibited an interesting activity with an IC50 of 181.04 and284.27 microg/mL, respectively.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
