Ethanolic extract from the fruits of Pimpinella anisoides, an aromatic plant and a spice, exhibitedactivity against AChE and BChE, with IC50 values of 227.5 and 362.1 μg/ml, respectively. The mostabundant constituents of the extract were trans-anethole, (+)-limonene and (+)-sabinene.trans-Anethole exhibited the highest activity against AChE and BChE with IC50 values of 134.7and 209.6 μg/ml, respectively. The bicyclic monoterpene (+)-sabinene exhibited a promisingactivity against AChE (IC50 of 176.5 μg/ml) and BChE (IC50 of 218.6 μg/ml).

Ethanolic extract from the fruits of Pimpinella anisoides, an aromatic plant and a spice, exhibitedactivity against AChE and BChE, with IC50 values of 227.5 and 362.1 μg/ml, respectively. The mostabundant constituents of the extract were trans-anethole, (+)-limonene and (+)-sabinene.trans-Anethole exhibited the highest activity against AChE and BChE with IC50 values of 134.7and 209.6 μg/ml, respectively. The bicyclic monoterpene (+)-sabinene exhibited a promisingactivity against AChE (IC50 of 176.5 μg/ml) and BChE (IC50 of 218.6 μg/ml).

Acetylcholinesterase and butyrylcholinesterase inhibition of ethanolic extract and monoterpenes from Pimpinella anisoides V Brig. (Apiaceae)

TUNDIS, ROSA;LOIZZO, Monica Rosa;MARCO BONESI;GIANCARLO ANTONIO STATTI;CONFORTI, FILOMENA
2009-01-01

Abstract

Ethanolic extract from the fruits of Pimpinella anisoides, an aromatic plant and a spice, exhibitedactivity against AChE and BChE, with IC50 values of 227.5 and 362.1 μg/ml, respectively. The mostabundant constituents of the extract were trans-anethole, (+)-limonene and (+)-sabinene.trans-Anethole exhibited the highest activity against AChE and BChE with IC50 values of 134.7and 209.6 μg/ml, respectively. The bicyclic monoterpene (+)-sabinene exhibited a promisingactivity against AChE (IC50 of 176.5 μg/ml) and BChE (IC50 of 218.6 μg/ml).
2009
Ethanolic extract from the fruits of Pimpinella anisoides, an aromatic plant and a spice, exhibitedactivity against AChE and BChE, with IC50 values of 227.5 and 362.1 μg/ml, respectively. The mostabundant constituents of the extract were trans-anethole, (+)-limonene and (+)-sabinene.trans-Anethole exhibited the highest activity against AChE and BChE with IC50 values of 134.7and 209.6 μg/ml, respectively. The bicyclic monoterpene (+)-sabinene exhibited a promisingactivity against AChE (IC50 of 176.5 μg/ml) and BChE (IC50 of 218.6 μg/ml).
Pimpinella anisoides; Terpenes; Cholinesterase inhibition activity
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11770/132230
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