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EnglishEthanolic extract from the fruits of Pimpinella anisoides, an aromatic plant and a spice, exhibited activity against AChE and BChE, with IC50 values of 227.5 and 362.1 μg/ml, respectively. The most abundant constituents of the extract were trans-anethole, (+)-limonene and (+)-sabinene. trans-Anethole exhibited the highest activity against AChE and BChE with IC50 values of 134.7 and 209.6 μg/ml, respectively. The bicyclic monoterpene (+)-sabinene exhibited a promising activity against AChE (IC50 of 176.5 μg/ml) and BChE (IC50 of 218.6 μg/ml).
Ethanolic extract from the fruits of Pimpinella anisoides, an aromatic plant and a spice, exhibited activity against AChE and BChE, with IC50 values of 227.5 and 362.1 μg/ml, respectively. The most abundant constituents of the extract were trans-anethole, (+)-limonene and (+)-sabinene. trans-Anethole exhibited the highest activity against AChE and BChE with IC50 values of 134.7 and 209.6 μg/ml, respectively. The bicyclic monoterpene (+)-sabinene exhibited a promising activity against AChE (IC50 of 176.5 μg/ml) and BChE (IC50 of 218.6 μg/ml).
Acetylcholinesterase and butyrylcholinesterase inhibition of ethanolic extract and monoterpenes from Pimpinella anisoides V Brig. (Apiaceae) / Federica, Menichini; Tundis, Rosa; Loizzo, Monica Rosa; Bonesi, Marco; Mariangela, Marrelli; GIANCARLO ANTONIO STATTI, ; Francesco, Menichini; Conforti, Filomena. - In: FITOTERAPIA. - ISSN 1971-551X. - 80(2009), pp. 297-300.
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| Titolo: | Acetylcholinesterase and butyrylcholinesterase inhibition of ethanolic extract and monoterpenes from Pimpinella anisoides V Brig. (Apiaceae) | |
| Autori: | ||
| Data di pubblicazione: | 2009 | |
| Rivista: | ||
| Citazione: | Acetylcholinesterase and butyrylcholinesterase inhibition of ethanolic extract and monoterpenes from Pimpinella anisoides V Brig. (Apiaceae) / Federica, Menichini; Tundis, Rosa; Loizzo, Monica Rosa; Bonesi, Marco; Mariangela, Marrelli; GIANCARLO ANTONIO STATTI, ; Francesco, Menichini; Conforti, Filomena. - In: FITOTERAPIA. - ISSN 1971-551X. - 80(2009), pp. 297-300. | |
| Handle: | http://hdl.handle.net/20.500.11770/132230 | |
| Appare nelle tipologie: | 1.1 Articolo in rivista |
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