Ally1 alcohols can be efficiently carbonylated to beta,gamma-unsaturated acids or esters in dimethylacetamide (DMA) or MeOH/DMA mixtures under relatively mild conditions (8O°C, 50-100 atm) using a simple catalytic system consisting of palladium iodide in the presence of thiourea as ligand. In the case of but-2-ene-1,4-diol, selectivation to methyl S-hydroxypent-3-enoate, 3,6-dihydro-1,2-pyrone or dimethyl hex-3-enedioate may be achieved.
A simple catalytic system for the substitutive carbonylation of allyl alcohols to beta,gamma-unsaturated acids or esters
GABRIELE, Bartolo;
1996-01-01
Abstract
Ally1 alcohols can be efficiently carbonylated to beta,gamma-unsaturated acids or esters in dimethylacetamide (DMA) or MeOH/DMA mixtures under relatively mild conditions (8O°C, 50-100 atm) using a simple catalytic system consisting of palladium iodide in the presence of thiourea as ligand. In the case of but-2-ene-1,4-diol, selectivation to methyl S-hydroxypent-3-enoate, 3,6-dihydro-1,2-pyrone or dimethyl hex-3-enedioate may be achieved.File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
