Chiral disubstituted oxindoles represent an important family of bioactive molecules. The construction of asymmetric quaternary carbon at cyclopentane ring is therefore a challenging problem for organic chemists. In the last years, many papers have appeared on asymmetric catalytic methods for the synthesis of these compounds and the literature on spirocyclic derivatives, 3-substituted-3-hydroxyoxindoles and 3-substituted-3-aminooxindoles has been largely reviewed. The literature on other hetero-substituted oxindoles has not fully reviewed after 2011. This review aims to fill this gap covering the literature on these topics until the end of 2016. A special section will be also devoted to indoline-thiones.
Scheda prodotto non validato
Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo
Titolo: | Catalytic Asymmetric Synthesis of Hetero-substituted Oxindoles |
Autori: | |
Data di pubblicazione: | 2017 |
Rivista: | |
Handle: | http://hdl.handle.net/20.500.11770/140184 |
Appare nelle tipologie: | 1.1 Articolo in rivista |