Electron impact ionized purine bases such as caffeine and its metabolites (theophylline, theobromine, paraxanthine, 1-methylxanthine, 3-methylxanthine and 7-methylxanthine) were characterized by tandem mass spectrometry. The direct analysis of human urinary extracts by tandem mass spectrometry allows the unambiguous identification of caffeine and its metabolites present simultaneously in the urine.

Electron impact ionized purine bases such as caffeine and its metabolites (theophylline, theobromine, paraxanthine, 1-methylxanthine, 3-methylxanthine and 7-methylxanthine) were characterized by tandem mass spectrometry. The direct analysis of human urinary extracts by tandem mass spectrometry allows the unambiguous identification of caffeine and its metabolites present simultaneously in the urine.

IDENTIFICATION OF CAFFEINE AND ITS METABOLITES IN HUMAN URINE EXTRACTS BY ELECTRON-IMPACT IONIZATION TANDEM MASS-SPECTROMETRY

LIGUORI, Angelo;SINDONA, Giovanni
1991-01-01

Abstract

Electron impact ionized purine bases such as caffeine and its metabolites (theophylline, theobromine, paraxanthine, 1-methylxanthine, 3-methylxanthine and 7-methylxanthine) were characterized by tandem mass spectrometry. The direct analysis of human urinary extracts by tandem mass spectrometry allows the unambiguous identification of caffeine and its metabolites present simultaneously in the urine.
1991
Electron impact ionized purine bases such as caffeine and its metabolites (theophylline, theobromine, paraxanthine, 1-methylxanthine, 3-methylxanthine and 7-methylxanthine) were characterized by tandem mass spectrometry. The direct analysis of human urinary extracts by tandem mass spectrometry allows the unambiguous identification of caffeine and its metabolites present simultaneously in the urine.
FAST-ATOM-BOMBARDMENT; HUMAN-PLASMA; THEOPHYLLINE
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11770/141612
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