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EnglishThe aluminium trichloride/toluene system is investigated as a novel, unusual and straightforward reagent for the removal of the 9-fluorenylmethoxycarbonyl (Fmoc) protecting group in the solution peptide synthesis. This procedure avoids any undesired side reactions, such as the frequently observed inversion of the amino acid configuration.
The aluminium trichloride/toluene system is investigated as a novel, unusual and straightforward reagent for the removal of the 9- fluorenylmethoxycarbonyl (Fmoc) protecting group in the solution peptide synthesis. This procedure avoids any undesired side reactions, such as the frequently observed inversion of the amino acid configuration.
New strategies for an efficient removal of the 9-fluorenylmethoxycarbonyl (Fmoc) protecting group in the peptide synthesis / Leggio, Antonella; Liguori, Angelo; Napoli, A; Siciliano, Carlo; Sindona, Giovanni. - In: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. - ISSN 1434-193X. - :4(2000), pp. 573-575.
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| Titolo: | New strategies for an efficient removal of the 9-fluorenylmethoxycarbonyl (Fmoc) protecting group in the peptide synthesis | |
| Autori: | ||
| Data di pubblicazione: | 2000 | |
| Rivista: | ||
| Citazione: | New strategies for an efficient removal of the 9-fluorenylmethoxycarbonyl (Fmoc) protecting group in the peptide synthesis / Leggio, Antonella; Liguori, Angelo; Napoli, A; Siciliano, Carlo; Sindona, Giovanni. - In: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. - ISSN 1434-193X. - :4(2000), pp. 573-575. | |
| Abstract: | The aluminium trichloride/toluene system is investigated as a novel, unusual and straightforward reagent for the removal of the 9-fluorenylmethoxycarbonyl (Fmoc) protecting group in the solution peptide synthesis. This procedure avoids any undesired side reactions, such as the frequently observed inversion of the amino acid configuration. | |
| Handle: | http://hdl.handle.net/20.500.11770/142655 | |
| Appare nelle tipologie: | 1.1 Articolo in rivista |
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