Objectives: To determine if the qualitative test (cytochemical) is more reliable than the quantitative test (differential pH-metry) in identifying heterozygous G6PD(-) subjects. Design and methods: Identification of heterozygous G6PD(-) subjects was done by the measurement of G6PD activity and by a cytochemical test. Results: A cytochemical test is more sensitive than differential pH-metry to identify heterozygous G6PD(-) subjects. Conclusions: A cytochemical test is a reliable method for mass screening for G6PD deficiency to identify G6PD(-) heterozygotes. (c) 2005 The Canadian Society of Clinical Chemists. All rights reserved.

Reliability of quantitative and qualitative tests to identify heterozygotes carrying severe or mild G6PD deficiency

CONDINO, Francesca;
2006

Abstract

Objectives: To determine if the qualitative test (cytochemical) is more reliable than the quantitative test (differential pH-metry) in identifying heterozygous G6PD(-) subjects. Design and methods: Identification of heterozygous G6PD(-) subjects was done by the measurement of G6PD activity and by a cytochemical test. Results: A cytochemical test is more sensitive than differential pH-metry to identify heterozygous G6PD(-) subjects. Conclusions: A cytochemical test is a reliable method for mass screening for G6PD deficiency to identify G6PD(-) heterozygotes. (c) 2005 The Canadian Society of Clinical Chemists. All rights reserved.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/20.500.11770/144936
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