Objectives: To determine if the qualitative test (cytochemical) is more reliable than the quantitative test (differential pH-metry) in identifying heterozygous G6PD(-) subjects. Design and methods: Identification of heterozygous G6PD(-) subjects was done by the measurement of G6PD activity and by a cytochemical test. Results: A cytochemical test is more sensitive than differential pH-metry to identify heterozygous G6PD(-) subjects. Conclusions: A cytochemical test is a reliable method for mass screening for G6PD deficiency to identify G6PD(-) heterozygotes. (c) 2005 The Canadian Society of Clinical Chemists. All rights reserved.
Reliability of quantitative and qualitative tests to identify heterozygotes carrying severe or mild G6PD deficiency
CONDINO, Francesca;
2006-01-01
Abstract
Objectives: To determine if the qualitative test (cytochemical) is more reliable than the quantitative test (differential pH-metry) in identifying heterozygous G6PD(-) subjects. Design and methods: Identification of heterozygous G6PD(-) subjects was done by the measurement of G6PD activity and by a cytochemical test. Results: A cytochemical test is more sensitive than differential pH-metry to identify heterozygous G6PD(-) subjects. Conclusions: A cytochemical test is a reliable method for mass screening for G6PD deficiency to identify G6PD(-) heterozygotes. (c) 2005 The Canadian Society of Clinical Chemists. All rights reserved.File in questo prodotto:
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