A convenient and simple approach for the recyclable catalytic synthesis of substituted quinolines ispresented. The method is based on CuCl2-catalyzed heterocyclization of readily available 1-(2-aminoaryl)-2-yn-1-ols in BmimBF4 as the solvent at 100 C for 15–24 h. The solvent–catalyst system could besuccessfully recycled up to six times without significant loss of activity.

A convenient and simple approach for the recyclable catalytic synthesis of substituted quinolines ispresented. The method is based on CuCl2-catalyzed heterocyclization of readily available 1-(2-aminoaryl)-2-yn-1-ols in BmimBF4 as the solvent at 100 °C for 15–24 h. The solvent–catalyst system could besuccessfully recycled up to six times without significant loss of activity.

Recyclable catalytic synthesis of substituted quinolines: copper-catalyzed heterocyclization of 1-(2-aminoaryl)-2-yn-1-ols in ionic liquids

GABRIELE, Bartolo;MANCUSO R;VELTRI, Lucia;
2009

Abstract

A convenient and simple approach for the recyclable catalytic synthesis of substituted quinolines ispresented. The method is based on CuCl2-catalyzed heterocyclization of readily available 1-(2-aminoaryl)-2-yn-1-ols in BmimBF4 as the solvent at 100 °C for 15–24 h. The solvent–catalyst system could besuccessfully recycled up to six times without significant loss of activity.
A convenient and simple approach for the recyclable catalytic synthesis of substituted quinolines ispresented. The method is based on CuCl2-catalyzed heterocyclization of readily available 1-(2-aminoaryl)-2-yn-1-ols in BmimBF4 as the solvent at 100 C for 15–24 h. The solvent–catalyst system could besuccessfully recycled up to six times without significant loss of activity.
Quinolines; Ionic liquids; Copper; cyclization; heterocycles
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11770/151367
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