A general methodology for the total synthesis of N-alkyl- and acylpolyamine derivatives is described which is based on the coupling of suitable N-tritylamino acids with amines followed by lithium aluminium hydride reduction of the thus obtained amides.
SIMPLE TOTAL SYNTHESES OF N-SUBSTITUTED POLYAMINE DERIVATIVES USING N-TRITYLAMINO ACIDS
SINDONA, Giovanni
1995-01-01
Abstract
A general methodology for the total synthesis of N-alkyl- and acylpolyamine derivatives is described which is based on the coupling of suitable N-tritylamino acids with amines followed by lithium aluminium hydride reduction of the thus obtained amides.File in questo prodotto:
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