The desire for new synthetic methodologies for the rapid construction of enantiomerically pure substituted indole has been a fruitful driving force for chemical research in the last few years. This research line has produced a stunning array of enantioselective technologies either metal or organocatalyzed. This critical review documents the development of organocatalytic indole alkylation strategies, until the end of 2009
Il desiderio di poter disporre di metodologie sintetiche enantioselettive per la costruzione di indoli sostituiti ha dato una spinta notevole alla ricerca chimica degli ultimo anni. Sono così state messe a punto una serie di reazioni sia metallo che organo-catalizzaite. Questa "critical review" ne documenta le strategie organocatalizzate fino alla fine del 2009.
Organocatalytic strategies for the asymmetric functionalization of indoles
DALPOZZO, Renato
2010-01-01
Abstract
The desire for new synthetic methodologies for the rapid construction of enantiomerically pure substituted indole has been a fruitful driving force for chemical research in the last few years. This research line has produced a stunning array of enantioselective technologies either metal or organocatalyzed. This critical review documents the development of organocatalytic indole alkylation strategies, until the end of 2009I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
