A base-free, recyclable approach for the conjugate addition of aliphatic nitro compounds to enones to give -nitro ketones is presented. Reactions are carried out in an ionic liquid with a basic anionic moiety, such as BmimNTf2, as the solvent, under mild conditions (25 °C for 24 h). The IL medium could be recycled several times without any appreciable loss of activity, after a simple extraction procedure for the separation of the reaction product.

Base-free conjugate addition of aliphatic nitro compounds to enones in BmimNTf2: a recyclable synthesis of gamma-nitro ketones

MANCUSO R.;GABRIELE, Bartolo
2012

Abstract

A base-free, recyclable approach for the conjugate addition of aliphatic nitro compounds to enones to give -nitro ketones is presented. Reactions are carried out in an ionic liquid with a basic anionic moiety, such as BmimNTf2, as the solvent, under mild conditions (25 °C for 24 h). The IL medium could be recycled several times without any appreciable loss of activity, after a simple extraction procedure for the separation of the reaction product.
Conjugate addition; Enones; Ionic Liquids; Nitro compounds; Gamma-nitro ketones
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11770/156645
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