The cadaverine derivatives 1-4 containing ethoxyalkyl groups of variable length in position 2, planned as model molecules for the diamine oxidase active site study, were prepared and characterized exploiting as key precursors both 5-(N,N-dimethylamino)pentanonitrile or ethyl 2-cyano-5-(N,N-dimethylamino)pentanoate.
C-alkylation of nitriles: a useful route to 2-ethoxyalkyl derivatives of cadaverine planned for enzyme study
PICCI, Nevio;IEMMA, Francesca
1993-01-01
Abstract
The cadaverine derivatives 1-4 containing ethoxyalkyl groups of variable length in position 2, planned as model molecules for the diamine oxidase active site study, were prepared and characterized exploiting as key precursors both 5-(N,N-dimethylamino)pentanonitrile or ethyl 2-cyano-5-(N,N-dimethylamino)pentanoate.File in questo prodotto:
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