Mass spectrometry and potentiometry studies of Al(III)–naringin complexes

Here we have studied the complexation of naringin with Al(III) under physiological conditions (i.e., at 37 C and in 0.16 mol L1 NaCl). Solubility and protonation constants of the ligand were first determined in order to evaluate the competition of naringin for the Al(III) and H+ ions. Speciation analysis made by potentiometric titrations and supported by UV data shows that a complexation occurs at a 1 : 1 ligandto-Al(III) stoichiometric ratio. Notably, these data combined with mass spectrometry results indicate that the complexation site is located on the b-hydroxy ketone moiety