The present review lists the papers and patents dealing with the class of polycondensed heterocycles called benzopyrroloxazines published in the last decades. The survey is limited to substances characterized by the presence of a bridgehead N atom, which means that the present N atom serves to connect different rings within the same molecule. In the case of benzopyrroloxazines, the bridgehead N atom belongs at the same time to the pyrrole and oxazine rings. All other compounds not possessing this feature were kept out accordingly. Relevant synthetic methods to such compounds have been outlined. Many different biological properties have been attributed to several functionalized derivatives of these heterocycles and cited within the review.

Benzopyrroloxazines containing a bridgehead nitrogen atom as promising scaffolds for the achievement of biologically active agents

Grande, Fedora
;
Occhiuzzi, Maria A.;Ioele, Giuseppina;Ragno, Gaetano;Garofalo, Antonio
2018

Abstract

The present review lists the papers and patents dealing with the class of polycondensed heterocycles called benzopyrroloxazines published in the last decades. The survey is limited to substances characterized by the presence of a bridgehead N atom, which means that the present N atom serves to connect different rings within the same molecule. In the case of benzopyrroloxazines, the bridgehead N atom belongs at the same time to the pyrrole and oxazine rings. All other compounds not possessing this feature were kept out accordingly. Relevant synthetic methods to such compounds have been outlined. Many different biological properties have been attributed to several functionalized derivatives of these heterocycles and cited within the review.
Biological activity; Oxazinoindoles; Polycondensed heterocycles; Synthetic methods; Pharmacology; Drug Discovery3003 Pharmaceutical Science; Organic Chemistry
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11770/280239
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