Genome-wide Analyses Identify KIF5A as a Novel ALS Gene

Nicolas, Aude; Kenna, Kevin P.; Renton, Alan E.; Ticozzi, Nicola; Faghri, Faraz; Chia, Ruth; Dominov, Janice A.; Kenna, Brendan J.; Nalls, Mike A.; Keagle, Pamela; Rivera, Alberto M.; Wouter van Rheenen,; Murphy, Natalie A.; van Vugt, Joke J. F. A.; Geiger, Joshua T.; Van der Spek, Rick A.; Pliner, Hannah A.; Shankaracharya,; Smith, Bradley N.; Marangi, Giuseppe; Topp, Simon D.; Abramzon, Yevgeniya; Athina Soragia Gkazi,; Eicher, John D.; Kenna, Aoife; Consortium, Italsgen; Mora, Gabriele; Calvo, Andrea; Mazzini, Letizia; Riva, Nilo; Mandrioli, Jessica; Caponnetto, Claudia; Battistini, Stefania; Volanti, Paolo; Vincenzo La Bella,; Conforti, F. L.; Borghero, Giuseppe; Messina, Sonia; Simone, Isabella L.; Trojsi, Francesca; Salvi, Fabrizio; Logullo, Francesco O.; D’Alfonso, Sandra; Corrado, Lucia; Capasso, Margherita; Ferrucci, Luigi; Genomic Translation for ALS Care (GTAC) Consortium,; Cristiane de Araujo Martins Moreno,; Kamalakaran, Sitharthan; Goldstein, David B.; ALS Sequencing Consortium,; Gitler, Aaron D.; Harris, Tim; Myers, Richard M.; NYGC ALS Consortium,; Phatnani, Hemali; Rajeeva Lochan Musunuri,; Uday Shankar Evani,; Abhyankar, Avinash; Zody, Michael C.; Answer ALS Foundation,; Kaye, Julia; Finkbeiner, Steven; Wyman, Stacia K.; Lenail, Alex; Lima, Leandro; Fraenkel, Ernest; Svendsen, Clive N.; Thompson, Leslie M.; Van Eyk, Jennifer E.; Berry, James D.; Miller, Timothy M.; Kolb, Stephen J.; Cudkowicz, Merit; Baxi, Emily; Clinical Research in ALS and Related Disorders for Therapeutic Development (CReATe) Consortium,; Benatar, Michael; Paul Taylor, J.; Rampersaud, Evadnie; Gang, Wu; Wuu, Joanne; Consortium, Slagen; Lauria, Giuseppe; Verde, Federico; Fogh, Isabella; Tiloca, Cinzia; Comi, Giacomo P.; Sorarù, Gianni; Cereda, Cristina; French ALS Consortium,; Corcia, Philippe; Laaksovirta, Hannu; Myllykangas, Liisa; Jansson, Lilja; Valori, Miko; Ealing, John; Hamdalla, Hisham; Rollinson, Sara; Pickering-Brown, Stuart; Orrell, Richard W.; Sidle, Katie C.; Malaspina, Andrea; Hardy, John; Singleton, Andrew B.; Johnson, Janel O.; Arepalli, Sampath; Sapp, Peter C.; McKenna-Yasek, Diane; Polak, Meraida; Asress, Seneshaw; Al-Sarraj, Safa; King, Andrew; Troakes, Claire; Vance, Caroline; Jacqueline de Belleroche,; Baas, Frank; ten Asbroek, Anneloor L. M. A.; José Luis Muñoz-Blanco,; Hernandez, Dena G.; Ding, Jinhui; Raphael Gibbs, J.; Scholz, Sonja W.; Mary Kay Floeter,; Campbell, Roy H.; Landi, Francesco; Bowser, Robert; Pulst, Stefan M.; Ravits, John M.; Macgowan, Daniel J. L.; Kirby, Janine; Pioro, Erik P.; Pamphlett, Roger; Broach, James; Gerhard, Glenn; Dunckley, Travis L.; Brady, Christopher B.; Kowall, Neil W.; Troncoso, Juan C.; Isabelle Le Ber,; Mouzat, Kevin; Lumbroso, Serge; Heiman-Patterson, Terry D.; Kamel, Freya; Ludo Van Den Bosch,; Baloh, Robert H.; Strom, Tim M.; Meitinger, Thomas; Shatunov, Aleksey; Van Eijk, Kristel R.; Mamede de Carvalho,; Kooyman, Maarten; Middelkoop, Bas; Moisse, Matthieu; Mclaughlin, Russell L.; Van Es, Michael A.; Weber, Markus; Boylan, Kevin B.; Marka Van Blitterswijk,; Rademakers, Rosa; Morrison, Karen E.; Nazli Basak, A.; Mora, Jesús S.; Drory, Vivian E.; Shaw, Pamela J.; Turner, Martin R.; Talbot, Kevin; Hardiman, Orla; Williams, Kelly L.; Fifita, Jennifer A.; Nicholson, Garth A.; Blair, Ian P.; Rouleau, Guy A.; Esteban-Pérez, Jesús; García-Redondo, Alberto; Al-Chalabi, Ammar; Project MinE ALS Sequencing Consortium,; Rogaeva, Ekaterina; Zinman, Lorne; Ostrow, Lyle W.; Maragakis, Nicholas J.; Rothstein, Jeffrey D.; Simmons, Zachary; Cooper-Knock, Johnathan; Brice, Alexis; Goutman, Stephen A.; Feldman, Eva L.; Gibson, Summer B.; Taroni, Franco; Ratti, Antonia; Gellera, Cinzia; Philip Van Damme,; Robberecht, Wim; Fratta, Pietro; Sabatelli, Mario; Lunetta, Christian; Ludolph, Albert C.; Andersen, Peter M.; Weishaupt, Jochen H.; Camu, William; Trojanowski, John Q.; Van Deerlin, Vivianna M.; Robert, H. Brown Jr.; van den Berg, Leonard H.; Veldink, Jan H.; Harms, Matthew B.; Glass, Jonathan D.; Stone, David J.; Tienari, Pentti; Silani, Vincenzo; Chiò, Adriano; Shaw, Christopher E.; Traynor, Bryan J.; Landers, John E.

doi:10.1016/j.neuron.2018.02.027

Genome-wide Analyses Identify KIF5A as a Novel ALS Gene

Aude Nicolas;Kevin P. Kenna;Alan E. Renton;Nicola Ticozzi;Faraz Faghri;Ruth Chia;Janice A. Dominov;Brendan J. Kenna;Mike A. Nalls;Pamela Keagle;Alberto M. Rivera;Wouter van Rheenen;Natalie A. Murphy;Joke J.F.A. van Vugt;Joshua T. Geiger;Rick A. Van der Spek;Hannah A. Pliner;Shankaracharya;Bradley N. Smith;Giuseppe Marangi;Simon D. Topp;Yevgeniya Abramzon;Athina Soragia Gkazi;John D. Eicher;Aoife Kenna;ITALSGEN Consortium;Gabriele Mora;Andrea Calvo;Letizia Mazzini;Nilo Riva;Jessica Mandrioli;Claudia Caponnetto;Stefania Battistini;Paolo Volanti;Vincenzo La Bella;Conforti F.L.;Giuseppe Borghero;Sonia Messina;Isabella L. Simone;Francesca Trojsi;Fabrizio Salvi;Francesco O. Logullo;Sandra D’Alfonso;Lucia Corrado;Margherita Capasso;Luigi Ferrucci;Cristiane de Araujo Martins Moreno;Sitharthan Kamalakaran;David B. Goldstein;ALS Sequencing Consortium;Aaron D. Gitler;Tim Harris;Richard M. Myers;NYGC ALS Consortium;Hemali Phatnani;Rajeeva Lochan Musunuri;Uday Shankar Evani;Avinash Abhyankar;Michael C. Zody;Answer ALS Foundation;Julia Kaye;Steven Finkbeiner;Stacia K. Wyman;Alex LeNail;Leandro Lima;Ernest Fraenkel;Clive N. Svendsen;Leslie M. Thompson;Jennifer E. Van Eyk;James D. Berry;Timothy M. Miller;Stephen J. Kolb;Merit Cudkowicz;Emily Baxi;Michael Benatar;J. Paul Taylor;Evadnie Rampersaud;Gang Wu;Joanne Wuu;SLAGEN Consortium;Giuseppe Lauria;Federico Verde;Isabella Fogh;Cinzia Tiloca;Giacomo P. Comi;Gianni Sorarù;Cristina Cereda;French ALS Consortium;Philippe Corcia;Hannu Laaksovirta;Liisa Myllykangas;Lilja Jansson;Miko Valori;John Ealing;Hisham Hamdalla;Sara Rollinson;Stuart Pickering-Brown;Richard W. Orrell;Katie C. Sidle;Andrea Malaspina;John Hardy;Andrew B. Singleton;Janel O. Johnson;Sampath Arepalli;Peter C. Sapp;Diane McKenna-Yasek;Meraida Polak;Seneshaw Asress;Safa Al-Sarraj;Andrew King;Claire Troakes;Caroline Vance;Jacqueline de Belleroche;Frank Baas;Anneloor L.M.A. ten Asbroek;José Luis Muñoz-Blanco;Dena G. Hernandez;Jinhui Ding;J. Raphael Gibbs;Sonja W. Scholz;Mary Kay Floeter;Roy H. Campbell;Francesco Landi;Robert Bowser;Stefan M. Pulst;John M. Ravits;Daniel J.L. MacGowan;Janine Kirby;Erik P. Pioro;Roger Pamphlett;James Broach;Glenn Gerhard;Travis L. Dunckley;Christopher B. Brady;Neil W. Kowall;Juan C. Troncoso;Isabelle Le Ber;Kevin Mouzat;Serge Lumbroso;Terry D. Heiman-Patterson;Freya Kamel;Ludo Van Den Bosch;Robert H. Baloh;Tim M. Strom;Thomas Meitinger;Aleksey Shatunov;Kristel R. Van Eijk;Mamede de Carvalho;Maarten Kooyman;Bas Middelkoop;Matthieu Moisse;Russell L. McLaughlin;Michael A. Van Es;Markus Weber;Kevin B. Boylan;Marka Van Blitterswijk;Rosa Rademakers;Karen E. Morrison;A. Nazli Basak;Jesús S. Mora;Vivian E. Drory;Pamela J. Shaw;Martin R. Turner;Kevin Talbot;Orla Hardiman;Kelly L. Williams;Jennifer A. Fifita;Garth A. Nicholson;Ian P. Blair;Guy A. Rouleau;Jesús Esteban-Pérez;Alberto García-Redondo;Ammar Al-Chalabi;Project MinE ALS Sequencing Consortium;Ekaterina Rogaeva;Lorne Zinman;Lyle W. Ostrow;Nicholas J. Maragakis;Jeffrey D. Rothstein;Zachary Simmons;Johnathan Cooper-Knock;Alexis Brice;Stephen A. Goutman;Eva L. Feldman;Summer B. Gibson;Franco Taroni;Antonia Ratti;Cinzia Gellera;Philip Van Damme;Wim Robberecht;Pietro Fratta;Mario Sabatelli;Christian Lunetta;Albert C. Ludolph;Peter M. Andersen;Jochen H. Weishaupt;William Camu;John Q. Trojanowski;Vivianna M. Van Deerlin;Robert H. Brown Jr.;Leonard H. van den Berg;Jan H. Veldink;Matthew B. Harms;Jonathan D. Glass;David J. Stone;Pentti Tienari;Vincenzo Silani;Adriano Chiò;Christopher E. Shaw;Bryan J. Traynor;John E. Landers

2018-01-01

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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11770/291717

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Genome-wide Analyses Identify KIF5A as a Novel ALS Gene

2018-01-01

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