Genome-wide Analyses Identify KIF5A as a Novel ALS Gene

Aude Nicolas;Kevin P. Kenna;Alan E. Renton;Nicola Ticozzi;Faraz Faghri;Ruth Chia;Janice A. Dominov;Brendan J. Kenna;Mike A. Nalls;Pamela Keagle;Alberto M. Rivera;Wouter van Rheenen;Natalie A. Murphy;Joke J.F.A. van Vugt;Joshua T. Geiger;Rick A. Van der Spek;Hannah A. Pliner;Shankaracharya;Bradley N. Smith;Giuseppe Marangi;Simon D. Topp;Yevgeniya Abramzon;Athina Soragia Gkazi;John D. Eicher;Aoife Kenna;ITALSGEN Consortium;Gabriele Mora;Andrea Calvo;Letizia Mazzini;Nilo Riva;Jessica Mandrioli;Claudia Caponnetto;Stefania Battistini;Paolo Volanti;Vincenzo La Bella;Conforti F.L.;Giuseppe Borghero;Sonia Messina;Isabella L. Simone;Francesca Trojsi;Fabrizio Salvi;Francesco O. Logullo;Sandra D’Alfonso;Lucia Corrado;Margherita Capasso;Luigi Ferrucci;Genomic Translation for ALS Care (GTAC) Consortium;Cristiane de Araujo Martins Moreno;Sitharthan Kamalakaran;David B. Goldstein;ALS Sequencing Consortium;Aaron D. Gitler;Tim Harris;Richard M. Myers;NYGC ALS Consortium;Hemali Phatnani;Rajeeva Lochan Musunuri;Uday Shankar Evani;Avinash Abhyankar;Michael C. Zody;Answer ALS Foundation;Julia Kaye;Steven Finkbeiner;Stacia K. Wyman;Alex LeNail;Leandro Lima;Ernest Fraenkel;Clive N. Svendsen;Leslie M. Thompson;Jennifer E. Van Eyk;James D. Berry;Timothy M. Miller;Stephen J. Kolb;Merit Cudkowicz;Emily Baxi;Clinical Research in ALS and Related Disorders for Therapeutic Development (CReATe) Consortium;Michael Benatar;J. Paul Taylor;Evadnie Rampersaud;Gang Wu;Joanne Wuu;SLAGEN Consortium;Giuseppe Lauria;Federico Verde;Isabella Fogh;Cinzia Tiloca;Giacomo P. Comi;Gianni Sorarù;Cristina Cereda;French ALS Consortium;Philippe Corcia;Hannu Laaksovirta;Liisa Myllykangas;Lilja Jansson;Miko Valori;John Ealing;Hisham Hamdalla;Sara Rollinson;Stuart Pickering-Brown;Richard W. Orrell;Katie C. Sidle;Andrea Malaspina;John Hardy;Andrew B. Singleton;Janel O. Johnson;Sampath Arepalli;Peter C. Sapp;Diane McKenna-Yasek;Meraida Polak;Seneshaw Asress;Safa Al-Sarraj;Andrew King;Claire Troakes;Caroline Vance;Jacqueline de Belleroche;Frank Baas;Anneloor L.M.A. ten Asbroek;José Luis Muñoz-Blanco;Dena G. Hernandez;Jinhui Ding;J. Raphael Gibbs;Sonja W. Scholz;Mary Kay Floeter;Roy H. Campbell;Francesco Landi;Robert Bowser;Stefan M. Pulst;John M. Ravits;Daniel J.L. MacGowan;Janine Kirby;Erik P. Pioro;Roger Pamphlett;James Broach;Glenn Gerhard;Travis L. Dunckley;Christopher B. Brady;Neil W. Kowall;Juan C. Troncoso;Isabelle Le Ber;Kevin Mouzat;Serge Lumbroso;Terry D. Heiman-Patterson;Freya Kamel;Ludo Van Den Bosch;Robert H. Baloh;Tim M. Strom;Thomas Meitinger;Aleksey Shatunov;Kristel R. Van Eijk;Mamede de Carvalho;Maarten Kooyman;Bas Middelkoop;Matthieu Moisse;Russell L. McLaughlin;Michael A. Van Es;Markus Weber;Kevin B. Boylan;Marka Van Blitterswijk;Rosa Rademakers;Karen E. Morrison;A. Nazli Basak;Jesús S. Mora;Vivian E. Drory;Pamela J. Shaw;Martin R. Turner;Kevin Talbot;Orla Hardiman;Kelly L. Williams;Jennifer A. Fifita;Garth A. Nicholson;Ian P. Blair;Guy A. Rouleau;Jesús Esteban-Pérez;Alberto García-Redondo;Ammar Al-Chalabi;Project MinE ALS Sequencing Consortium;Ekaterina Rogaeva;Lorne Zinman;Lyle W. Ostrow;Nicholas J. Maragakis;Jeffrey D. Rothstein;Zachary Simmons;Johnathan Cooper-Knock;Alexis Brice;Stephen A. Goutman;Eva L. Feldman;Summer B. Gibson;Franco Taroni;Antonia Ratti;Cinzia Gellera;Philip Van Damme;Wim Robberecht;Pietro Fratta;Mario Sabatelli;Christian Lunetta;Albert C. Ludolph;Peter M. Andersen;Jochen H. Weishaupt;William Camu;John Q. Trojanowski;Vivianna M. Van Deerlin;Robert H. Brown Jr.;Leonard H. van den Berg;Jan H. Veldink;Matthew B. Harms;Jonathan D. Glass;David J. Stone;Pentti Tienari;Vincenzo Silani;Adriano Chiò;Christopher E. Shaw;Bryan J. Traynor;John E. Landers

2018