1,2,3-triazoles represent a functional heterocyclic core that has been at the center of modern organic chemistry since the beginning of click chemistry. Being a versatile framework, such an aromatic ring can be observed in uncountable molecules useful in medicine and photochemistry, just to name a few. This review summarizes the progress achieved in their synthesis from 2015 to today, with particular emphasis on the development of new catalytic and eco-compatible appproaches. In doing so, we subdivided the report based on their degree of functionalization and, for each subparagraph, we outlined the role of the catalyst employed.

Recent Progress in Catalytic Synthesis of 1,2,3-Triazoles

Antonio De Nino
;
Loredana Maiuolo
;
Paola Costanzo
;
Vincenzo Algieri;Antonio Jiritano;Fabrizio Olivito;Matteo Antonio Tallarida
2021-01-01

Abstract

1,2,3-triazoles represent a functional heterocyclic core that has been at the center of modern organic chemistry since the beginning of click chemistry. Being a versatile framework, such an aromatic ring can be observed in uncountable molecules useful in medicine and photochemistry, just to name a few. This review summarizes the progress achieved in their synthesis from 2015 to today, with particular emphasis on the development of new catalytic and eco-compatible appproaches. In doing so, we subdivided the report based on their degree of functionalization and, for each subparagraph, we outlined the role of the catalyst employed.
2021
1,2,3-triazoles; click chemistry; 1,3-dipolar cycloaddition; Huisgen reactions; triazole synthesis
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11770/324114
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