This work involves the synthesis and application of nanosized keratin-coated gold particles; a protein extracted from wool. Their effect against a specific type of brain cancer, glioblastoma, is investigated. Gold nanoparticles have been the subject of a lot of interest recently due to their ability to convert light energy into heat energy. When the keratin-coated nanoparticles were up taken into cancerous cells and exposed to light from a laser, they heated up and killed the cancer cells. The next step for this research is to conduct more detailed studies in animals, hopefully leading to a new generation of nanosized therapeutics in the fight against cancer.

Biomimetic keratin gold nanoparticle-mediated in vitro photothermal therapy on glioblastoma multiforme

Alexa Guglielmelli
Investigation
;
Luciano De Sio
Supervision
2021-01-01

Abstract

This work involves the synthesis and application of nanosized keratin-coated gold particles; a protein extracted from wool. Their effect against a specific type of brain cancer, glioblastoma, is investigated. Gold nanoparticles have been the subject of a lot of interest recently due to their ability to convert light energy into heat energy. When the keratin-coated nanoparticles were up taken into cancerous cells and exposed to light from a laser, they heated up and killed the cancer cells. The next step for this research is to conduct more detailed studies in animals, hopefully leading to a new generation of nanosized therapeutics in the fight against cancer.
2021
cancer gold nanoparticles keratin optics thermoplasmonics
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11770/341633
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