A new structural form of the already reported silver-based 1D coordination polymer (CP) [(bpy)Ag (OTf)]∞ (bpy = 2,2′-bipyridine; OTf = trifluoromethanesulfonate) has been synthesized and fully characterized through single-crystal and powder XRD, DSC, and FTIR analysis. The reaction of both structural forms of the Ag(I) CP with curcumin (curc) afforded the formation of a new solid form, specifically an inorganic polymeric co-crystal between curc and [(bpy)Ag (OTf)] in a 1: 4 molar ratio, respectively. The co-crystal has been characterized both in solution and in the solid state through 1H NMR, PXRD, DSC, IR, and UV–vis spectroscopies. In addition, a thorough computational study has been carried out to reveal the possible interaction modes between the co-crystal components. The Ag(I) compounds here presented have been preliminarily tested for antimicrobial activity against Staphylococcus aureus and Escherichia coli strains, all showing promising results.
Conjugation of a Silver-Based Coordination Polymer with Curcumin: A New Case of an Inorganic Polymeric Co-crystal
Crispini A.;La Deda M.;Di Maio G.;Godbert N.;Tagarelli A.;Elliani R.;Candreva A.;De Rose R.;Aiello I.;Scarpelli F.
2023-01-01
Abstract
A new structural form of the already reported silver-based 1D coordination polymer (CP) [(bpy)Ag (OTf)]∞ (bpy = 2,2′-bipyridine; OTf = trifluoromethanesulfonate) has been synthesized and fully characterized through single-crystal and powder XRD, DSC, and FTIR analysis. The reaction of both structural forms of the Ag(I) CP with curcumin (curc) afforded the formation of a new solid form, specifically an inorganic polymeric co-crystal between curc and [(bpy)Ag (OTf)] in a 1: 4 molar ratio, respectively. The co-crystal has been characterized both in solution and in the solid state through 1H NMR, PXRD, DSC, IR, and UV–vis spectroscopies. In addition, a thorough computational study has been carried out to reveal the possible interaction modes between the co-crystal components. The Ag(I) compounds here presented have been preliminarily tested for antimicrobial activity against Staphylococcus aureus and Escherichia coli strains, all showing promising results.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
