: It is now well established that lifestyle, particularly eating habits, modulates the syn-thesis and action of microRNAs (miRNAs). In particular, several nutritional schemes have proven effective in improving body composition, but molecular mechanisms still need to be fully under-stood. Within the complex physiological network of food intake regulation, it is essential to un-derstand the changes in endocrine activity after the reduction of adipose tissue during a weight loss program. This could be the key to identifying the optimal endocrine profile in high respond-ers, the assessment of musculoskeletal status, and long-term management. In this review, we summarize the state of the art regarding miRNAs as a function of weight loss and as a mechanistic regulator of the effectiveness of the nutritional program.

MicroRNAs and Diet-induced Weight Loss: What's the Link?

Caroleo, Maria Cristina;Cione, Erika
2023-01-01

Abstract

: It is now well established that lifestyle, particularly eating habits, modulates the syn-thesis and action of microRNAs (miRNAs). In particular, several nutritional schemes have proven effective in improving body composition, but molecular mechanisms still need to be fully under-stood. Within the complex physiological network of food intake regulation, it is essential to un-derstand the changes in endocrine activity after the reduction of adipose tissue during a weight loss program. This could be the key to identifying the optimal endocrine profile in high respond-ers, the assessment of musculoskeletal status, and long-term management. In this review, we summarize the state of the art regarding miRNAs as a function of weight loss and as a mechanistic regulator of the effectiveness of the nutritional program.
2023
adipose tissue
antagomiRs
food intake
ketogenic diet
ketogenic dietmicroRNAs
microRNAs
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11770/360538
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