A series of fused heterocyclic compounds based on a pyrrolizinone structure have been prepared fromortho-(1H-pyrrol-1-yl)aryl and heteroaryl carboxylic acids by intramolecular Friedel–Crafts acylationpromoted by bis(trichloromethyl) carbonate, in generally good yield without using Lewis acid catalysts.

A series of fused heterocyclic compounds based on a pyrrolizinone structure have been prepared fromortho-(1H-pyrrol-1-yl)aryl and heteroaryl carboxylic acids by intramolecular Friedel–Crafts acylationpromoted by bis(trichloromethyl) carbonate, in generally good yield without using Lewis acid catalysts.

Direct cyclization of ortho-(1H-pyrrol-1-yl)aryl and heteroaryl carboxylic acids into fused pyrrolizinones

AIELLO, Francesca
;
Garofalo A;GRANDE, Fedora
2010-01-01

Abstract

A series of fused heterocyclic compounds based on a pyrrolizinone structure have been prepared fromortho-(1H-pyrrol-1-yl)aryl and heteroaryl carboxylic acids by intramolecular Friedel–Crafts acylationpromoted by bis(trichloromethyl) carbonate, in generally good yield without using Lewis acid catalysts.
2010
A series of fused heterocyclic compounds based on a pyrrolizinone structure have been prepared fromortho-(1H-pyrrol-1-yl)aryl and heteroaryl carboxylic acids by intramolecular Friedel–Crafts acylationpromoted by bis(trichloromethyl) carbonate, in generally good yield without using Lewis acid catalysts.
Fused pyrrole derivatives; Ring closure reactions; Friedel–Crafts acylation
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11770/131138
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