A series of fused heterocyclic compounds based on a pyrrolizinone structure have been prepared fromortho-(1H-pyrrol-1-yl)aryl and heteroaryl carboxylic acids by intramolecular Friedel–Crafts acylationpromoted by bis(trichloromethyl) carbonate, in generally good yield without using Lewis acid catalysts.
A series of fused heterocyclic compounds based on a pyrrolizinone structure have been prepared fromortho-(1H-pyrrol-1-yl)aryl and heteroaryl carboxylic acids by intramolecular Friedel–Crafts acylationpromoted by bis(trichloromethyl) carbonate, in generally good yield without using Lewis acid catalysts.
Direct cyclization of ortho-(1H-pyrrol-1-yl)aryl and heteroaryl carboxylic acids into fused pyrrolizinones
AIELLO, Francesca
;Garofalo A;GRANDE, Fedora
2010-01-01
Abstract
A series of fused heterocyclic compounds based on a pyrrolizinone structure have been prepared fromortho-(1H-pyrrol-1-yl)aryl and heteroaryl carboxylic acids by intramolecular Friedel–Crafts acylationpromoted by bis(trichloromethyl) carbonate, in generally good yield without using Lewis acid catalysts.File in questo prodotto:
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