A new restricted access materials combined to Molecularly imprinted polymers (RAM-MIP)with hydrophilic external layer were prepared and their applicability in p-acetaminophenol (AMP) selective recognition and release was evaluated. Glycidilmethacrylate (GMA)was used as pro-hydrophilic co-monomer, and GMA epoxide ring opening with perchloricacid was performed for the hydrophilic modification of polymeric surface. Morphological and hydrophilic properties by scanning electron microscopy and water content measurement were determined and recognition and selectivity properties of RAM-MIP were compared to the unmodified MIP. With RAM-MIP, both hydrophobic non-specific interactionsbetween template or its analogues and polymeric matrices, and bovine serum albumin absorption were drastically reduced
New restricted access materials combined to molecularly imprinted polymers for selective recognition/release in water media
PUOCI F;IEMMA F;CIRILLO G;CURCIO M;PARISI OI;SPIZZIRRI UG;PICCI N
2009-01-01
Abstract
A new restricted access materials combined to Molecularly imprinted polymers (RAM-MIP)with hydrophilic external layer were prepared and their applicability in p-acetaminophenol (AMP) selective recognition and release was evaluated. Glycidilmethacrylate (GMA)was used as pro-hydrophilic co-monomer, and GMA epoxide ring opening with perchloricacid was performed for the hydrophilic modification of polymeric surface. Morphological and hydrophilic properties by scanning electron microscopy and water content measurement were determined and recognition and selectivity properties of RAM-MIP were compared to the unmodified MIP. With RAM-MIP, both hydrophobic non-specific interactionsbetween template or its analogues and polymeric matrices, and bovine serum albumin absorption were drastically reducedI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
