Aim: Angiotensin ll (Ang II) regulates the Atrial Natriuretic Peptide and Brain Natriuretic peptide levels in cardiac cells, but its action at the C-Type Natriuretic Peptide level is not clear. We examined whether Ang II induced significant modulation of CNP levels in hirman umbilical vein endothelial cells (HVECS) and the involvement Of the voltage operated calcium channel expressed in the endothelial cell: T-Type calcium channel (TCC) and L-Type calcium channel (LCC). We further investigated the role of ATI receptor in this mechanism.
The voltage calcium channels are involved in the CNP levels’s modulation by Ang II in the Human Umbelical Vein Endothelial Cells
MARTINO G;BRUNO, Rosalinda
2009-01-01
Abstract
Aim: Angiotensin ll (Ang II) regulates the Atrial Natriuretic Peptide and Brain Natriuretic peptide levels in cardiac cells, but its action at the C-Type Natriuretic Peptide level is not clear. We examined whether Ang II induced significant modulation of CNP levels in hirman umbilical vein endothelial cells (HVECS) and the involvement Of the voltage operated calcium channel expressed in the endothelial cell: T-Type calcium channel (TCC) and L-Type calcium channel (LCC). We further investigated the role of ATI receptor in this mechanism.File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
