FRATTARUOLO, LUCA
FRATTARUOLO, LUCA
Dipartimento di Farmacia e Scienze della Salute e della Nutrizione
3-Amino-alkylated indoles: Unexplored green products acting as anti-inflammatory agents
2019-01-01 Mazzotta, S.; Frattaruolo, L.; Brindisi, M.; Ulivieri, C.; Vanni, F.; Brizzi, A.; Carullo, G.; Cappello, A. R.; Aiello, F.
5-(Carbamoylmethylene)-oxazolidin-2-ones as a Promising Class of Heterocycles Inducing Apoptosis Triggered by Increased ROS Levels and Mitochondrial Dysfunction in Breast and Cervical Cancer
2020-01-01 Armentano, B.; Curcio, R.; Brindisi, M.; Mancuso, R.; Rago, V.; Ziccarelli, I.; Frattaruolo, L.; Fiorillo, M.; Dolce, V.; Gabriele, B.; Cappello, A. R.
A Genomics-Based Approach Identifies a Thioviridamide-Like Compound with Selective Anticancer Activity
2017-01-01 Frattaruolo, Luca; Lacret, Rodney; Cappello, Anna Rita; Truman, Andrew W.
A Picrocrocin-Enriched Fraction from a Saffron Extract Affects Lipid Homeostasis in HepG2 Cells through a Non-Statin-like Mode
2023-01-01 Frattaruolo, L.; Marra, F.; Lauria, G.; Siciliano, C.; Curcio, R.; Muto, L.; Brindisi, M.; Aiello, D.; Napoli, A.; Fiermonte, G.; Cappello, A. R.; Fiorillo, M.; Ahmed, A.; Dolce, V.
A stereoselective, multicomponent catalytic carbonylative approach to a new class of α,β-unsaturated γ-lactam derivatives
2021-01-01 Mancuso, R.; Ziccarelli, I.; Brindisi, M.; Altomare, C. D.; Frattaruolo, L.; Falcicchio, A.; Della Ca', N.; Cappello, A. R.; Gabriele, B.
Anticancer potential of novel α,β-unsaturated γ-lactam derivatives targeting the PI3K/AKT signaling pathway
2021-01-01 Brindisi, M.; Frattaruolo, L.; Mancuso, R.; Palumbo Piccionello, A.; Ziccarelli, I.; Catto, M.; Nicolotti, O.; Altomare, C. D.; Gabriele, B.; Cappello, A. R.
Antioxidant and Anti-Inflammatory Activities of Flavanones from Glycyrrhiza glabra L. (licorice) Leaf Phytocomplexes: Identification of Licoflavanone as a Modulator of NF-kB/MAPK Pathway
2019-01-01 Frattaruolo, L.; Carullo, G.; Brindisi, M.; Mazzotta, S.; Bellissimo, L.; Rago, V.; Curcio, R.; Dolce, V.; Aiello, F.; Cappello, A. R.
Bortezomib-loaded mesoporous silica nanoparticles selectively alter metabolism and induce death in multiple myeloma cells
2020-01-01 Nigro, A; Frattaruolo, L; Fava, M; De Napoli, I; Greco, M; Comandè, A; De Santo, M; Pellegrino, M; Ricci, E; Giordano, F; Perrotta, I; Leggio, A; Pasqua, L; Sisci, D; Cappello, Ar; Morelli, C
CD44-targeted nanoparticles with GSH-responsive activity as powerful therapeutic agents against breast cancer
2022-01-01 Brindisi, M.; Curcio, M.; Frattaruolo, L.; Cirillo, G.; Leggio, A.; Rago, V.; Nicoletta, F. P.; Cappello, A. R.; Iemma, F.
Chemical Profile and Bioactivity of Rubus idaeus L. Fruits Grown in Conventional and Aeroponic Systems
2024-01-01 La Torre, C.; Loizzo, M. R.; Frattaruolo, L.; Plastina, P.; Grisolia, A.; Armentano, B.; Cappello, M. S.; Cappello, A. R.; Tundis, R.
Chemical profile, antioxidant, anti-inflammatory, and anti-cancer effects of italian Salvia rosmarinus spenn. Methanol leaves extracts
2020-01-01 Brindisi, M.; Bouzidi, C.; Frattaruolo, L.; Loizzo, M. R.; Tundis, R.; Dugay, A.; Deguin, B.; Cappello, A. R.; Cappello, M. S.
Cholesterol and Mevalonate: Two Metabolites Involved in Breast Cancer Progression and Drug Resistance through the ERRα Pathway
2020-01-01 Brindisi, M.; Fiorillo, M.; Frattaruolo, L.; Sotgia, F.; Lisanti, M. P.; Cappello, A. R.
Corrigendum to “Naturally occurring sesquiterpene lactones and their semi-synthetic derivatives modulate PGE2 levels by decreasing COX2 activity and expression” [Heliyon 5 (3) (March 2019) e01366] (Heliyon (2019) 5(3), (S2405844018347509), (10.1016/j.heliyon.2019.e01366))
2019-01-01 Perri, F.; Frattaruolo, L.; Haworth, I.; Brindisi, M.; El-magboub, A.; Ferrario, A.; Gomer, C.; Aiello, F.; Adams, J. D.
Effect of curcumin on prostate cancer prevention and treatment: molecular and metabolic mechanisms
2023-01-01 Bevacqua, Emilia; Cirillo, Giuseppe; Frattaruolo, Luca; Cappello, Anna Rita; Tucci, Paola
Enhancing the Anticancer and Anti-Inflammatory Properties of Curcumin in Combination with Quercetin, for the Prevention and Treatment of Prostate Cancer
2023-01-01 Pellegrino, M.; Bevacqua, E.; Frattaruolo, L.; Cappello, A. R.; Aquaro, S.; Tucci, P.
ERRα PATHWAY AND ENDOCRINE RESISTANCE ON BREAST CANCER: CHOLESTEROL AND MEVALONATE INVOLVEMENT
2019-01-01 Brindisi, M.; Fiorillo, M.; Frattaruolo, L.; Curcio, R.; Dolce, V.; Sotgia, F.; Lisanti, M. P.; Cappello, A. R.
Exploiting Glycyrrhiza glabra L. (Licorice) Flavanones: Licoflavanone’s Impact on Breast Cancer Cell Bioenergetics
2024-01-01 Frattaruolo, Luca; Lauria, Graziantonio; Aiello, Francesca; Carullo, Gabriele; Curcio, Rosita; Fiorillo, Marco; Campiani, Giuseppe; Dolce, Vincenza; Cappello, Anna Rita
Exploration of piperazine-derived thioureas as antibacterial and anti-inflammatory agents. In vitro evaluation against clinical isolates of colistin-resistant Acinetobacter baumannii
2020-01-01 Mazzotta, S.; Cebrero-Cangueiro, T.; Frattaruolo, L.; Vega-Holm, M.; Carretero-Ledesma, M.; Sanchez-Cespedes, J.; Cappello, A. R.; Aiello, F.; Pachon, J.; Vega-Perez, J. M.; Iglesias-Guerra, F.; Pachon-Ibanez, M. E.
Functional characterization of the partially purified Sac1p-independent adenine nucleotide transport system (ANTS) from yeast endoplasmic reticulum
2018-01-01 Li, Yuan; Cappello, Anna Rita; Muto, Luigina; Martello, Emanuela; Madeo, Marianna; Curcio, Rosita; Lunetti, Paola; Raho, Susanna; Zaffino, Francesco; Frattaruolo, Luca; Lappano, Rosamaria; Malivindi, Rocco; Maggiolini, Marcello; Aiello, Donatella; Piazzolla, Carmela; Capobianco, Loredana; Fiermonte, Giuseppe; Dolce, Vincenza
GENOMICS-BASED DISCOVERY AND ANTICANCER ACTIVITY ASSESSMENT OF NEW THIOVIRIDAMIDE-LIKE MOLECULES PRODUCED BY ACTINOBACTERIA
2019-01-01 Frattaruolo, L.; Fiorillo, M.; Brindisi, M.; Lacret, R.; Curcio, R.; Dolce, V.; Truman, A. W.; Sotgia, F.; Lisanti, M. P.; Cappello, A. R.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 3-Amino-alkylated indoles: Unexplored green products acting as anti-inflammatory agents | 1-gen-2019 | Mazzotta, S.; Frattaruolo, L.; Brindisi, M.; Ulivieri, C.; Vanni, F.; Brizzi, A.; Carullo, G.; Cappello, A. R.; Aiello, F. | |
| 5-(Carbamoylmethylene)-oxazolidin-2-ones as a Promising Class of Heterocycles Inducing Apoptosis Triggered by Increased ROS Levels and Mitochondrial Dysfunction in Breast and Cervical Cancer | 1-gen-2020 | Armentano, B.; Curcio, R.; Brindisi, M.; Mancuso, R.; Rago, V.; Ziccarelli, I.; Frattaruolo, L.; Fiorillo, M.; Dolce, V.; Gabriele, B.; Cappello, A. R. | |
| A Genomics-Based Approach Identifies a Thioviridamide-Like Compound with Selective Anticancer Activity | 1-gen-2017 | Frattaruolo, Luca; Lacret, Rodney; Cappello, Anna Rita; Truman, Andrew W. | |
| A Picrocrocin-Enriched Fraction from a Saffron Extract Affects Lipid Homeostasis in HepG2 Cells through a Non-Statin-like Mode | 1-gen-2023 | Frattaruolo, L.; Marra, F.; Lauria, G.; Siciliano, C.; Curcio, R.; Muto, L.; Brindisi, M.; Aiello, D.; Napoli, A.; Fiermonte, G.; Cappello, A. R.; Fiorillo, M.; Ahmed, A.; Dolce, V. | |
| A stereoselective, multicomponent catalytic carbonylative approach to a new class of α,β-unsaturated γ-lactam derivatives | 1-gen-2021 | Mancuso, R.; Ziccarelli, I.; Brindisi, M.; Altomare, C. D.; Frattaruolo, L.; Falcicchio, A.; Della Ca', N.; Cappello, A. R.; Gabriele, B. | |
| Anticancer potential of novel α,β-unsaturated γ-lactam derivatives targeting the PI3K/AKT signaling pathway | 1-gen-2021 | Brindisi, M.; Frattaruolo, L.; Mancuso, R.; Palumbo Piccionello, A.; Ziccarelli, I.; Catto, M.; Nicolotti, O.; Altomare, C. D.; Gabriele, B.; Cappello, A. R. | |
| Antioxidant and Anti-Inflammatory Activities of Flavanones from Glycyrrhiza glabra L. (licorice) Leaf Phytocomplexes: Identification of Licoflavanone as a Modulator of NF-kB/MAPK Pathway | 1-gen-2019 | Frattaruolo, L.; Carullo, G.; Brindisi, M.; Mazzotta, S.; Bellissimo, L.; Rago, V.; Curcio, R.; Dolce, V.; Aiello, F.; Cappello, A. R. | |
| Bortezomib-loaded mesoporous silica nanoparticles selectively alter metabolism and induce death in multiple myeloma cells | 1-gen-2020 | Nigro, A; Frattaruolo, L; Fava, M; De Napoli, I; Greco, M; Comandè, A; De Santo, M; Pellegrino, M; Ricci, E; Giordano, F; Perrotta, I; Leggio, A; Pasqua, L; Sisci, D; Cappello, Ar; Morelli, C | |
| CD44-targeted nanoparticles with GSH-responsive activity as powerful therapeutic agents against breast cancer | 1-gen-2022 | Brindisi, M.; Curcio, M.; Frattaruolo, L.; Cirillo, G.; Leggio, A.; Rago, V.; Nicoletta, F. P.; Cappello, A. R.; Iemma, F. | |
| Chemical Profile and Bioactivity of Rubus idaeus L. Fruits Grown in Conventional and Aeroponic Systems | 1-gen-2024 | La Torre, C.; Loizzo, M. R.; Frattaruolo, L.; Plastina, P.; Grisolia, A.; Armentano, B.; Cappello, M. S.; Cappello, A. R.; Tundis, R. | |
| Chemical profile, antioxidant, anti-inflammatory, and anti-cancer effects of italian Salvia rosmarinus spenn. Methanol leaves extracts | 1-gen-2020 | Brindisi, M.; Bouzidi, C.; Frattaruolo, L.; Loizzo, M. R.; Tundis, R.; Dugay, A.; Deguin, B.; Cappello, A. R.; Cappello, M. S. | |
| Cholesterol and Mevalonate: Two Metabolites Involved in Breast Cancer Progression and Drug Resistance through the ERRα Pathway | 1-gen-2020 | Brindisi, M.; Fiorillo, M.; Frattaruolo, L.; Sotgia, F.; Lisanti, M. P.; Cappello, A. R. | |
| Corrigendum to “Naturally occurring sesquiterpene lactones and their semi-synthetic derivatives modulate PGE2 levels by decreasing COX2 activity and expression” [Heliyon 5 (3) (March 2019) e01366] (Heliyon (2019) 5(3), (S2405844018347509), (10.1016/j.heliyon.2019.e01366)) | 1-gen-2019 | Perri, F.; Frattaruolo, L.; Haworth, I.; Brindisi, M.; El-magboub, A.; Ferrario, A.; Gomer, C.; Aiello, F.; Adams, J. D. | |
| Effect of curcumin on prostate cancer prevention and treatment: molecular and metabolic mechanisms | 1-gen-2023 | Bevacqua, Emilia; Cirillo, Giuseppe; Frattaruolo, Luca; Cappello, Anna Rita; Tucci, Paola | |
| Enhancing the Anticancer and Anti-Inflammatory Properties of Curcumin in Combination with Quercetin, for the Prevention and Treatment of Prostate Cancer | 1-gen-2023 | Pellegrino, M.; Bevacqua, E.; Frattaruolo, L.; Cappello, A. R.; Aquaro, S.; Tucci, P. | |
| ERRα PATHWAY AND ENDOCRINE RESISTANCE ON BREAST CANCER: CHOLESTEROL AND MEVALONATE INVOLVEMENT | 1-gen-2019 | Brindisi, M.; Fiorillo, M.; Frattaruolo, L.; Curcio, R.; Dolce, V.; Sotgia, F.; Lisanti, M. P.; Cappello, A. R. | |
| Exploiting Glycyrrhiza glabra L. (Licorice) Flavanones: Licoflavanone’s Impact on Breast Cancer Cell Bioenergetics | 1-gen-2024 | Frattaruolo, Luca; Lauria, Graziantonio; Aiello, Francesca; Carullo, Gabriele; Curcio, Rosita; Fiorillo, Marco; Campiani, Giuseppe; Dolce, Vincenza; Cappello, Anna Rita | |
| Exploration of piperazine-derived thioureas as antibacterial and anti-inflammatory agents. In vitro evaluation against clinical isolates of colistin-resistant Acinetobacter baumannii | 1-gen-2020 | Mazzotta, S.; Cebrero-Cangueiro, T.; Frattaruolo, L.; Vega-Holm, M.; Carretero-Ledesma, M.; Sanchez-Cespedes, J.; Cappello, A. R.; Aiello, F.; Pachon, J.; Vega-Perez, J. M.; Iglesias-Guerra, F.; Pachon-Ibanez, M. E. | |
| Functional characterization of the partially purified Sac1p-independent adenine nucleotide transport system (ANTS) from yeast endoplasmic reticulum | 1-gen-2018 | Li, Yuan; Cappello, Anna Rita; Muto, Luigina; Martello, Emanuela; Madeo, Marianna; Curcio, Rosita; Lunetti, Paola; Raho, Susanna; Zaffino, Francesco; Frattaruolo, Luca; Lappano, Rosamaria; Malivindi, Rocco; Maggiolini, Marcello; Aiello, Donatella; Piazzolla, Carmela; Capobianco, Loredana; Fiermonte, Giuseppe; Dolce, Vincenza | |
| GENOMICS-BASED DISCOVERY AND ANTICANCER ACTIVITY ASSESSMENT OF NEW THIOVIRIDAMIDE-LIKE MOLECULES PRODUCED BY ACTINOBACTERIA | 1-gen-2019 | Frattaruolo, L.; Fiorillo, M.; Brindisi, M.; Lacret, R.; Curcio, R.; Dolce, V.; Truman, A. W.; Sotgia, F.; Lisanti, M. P.; Cappello, A. R. |