LAPPANO, Rosamaria
 Distribuzione geografica
Continente #
EU - Europa 5.168
NA - Nord America 4.984
AS - Asia 3.728
SA - Sud America 955
AF - Africa 267
Continente sconosciuto - Info sul continente non disponibili 9
OC - Oceania 9
Totale 15.120
Nazione #
US - Stati Uniti d'America 4.831
RU - Federazione Russa 2.420
SG - Singapore 1.789
CN - Cina 768
UA - Ucraina 726
BR - Brasile 725
IT - Italia 535
DE - Germania 501
VN - Vietnam 471
AT - Austria 317
SE - Svezia 209
SN - Senegal 162
FI - Finlandia 143
HK - Hong Kong 127
KR - Corea 113
TR - Turchia 96
AR - Argentina 88
CA - Canada 86
IN - India 73
GB - Regno Unito 71
NL - Olanda 54
FR - Francia 49
BD - Bangladesh 48
ID - Indonesia 46
EC - Ecuador 45
MX - Messico 41
IQ - Iraq 34
BE - Belgio 32
CO - Colombia 31
ZA - Sudafrica 29
PK - Pakistan 28
CZ - Repubblica Ceca 27
JP - Giappone 26
PL - Polonia 22
MA - Marocco 19
PE - Perù 14
ES - Italia 13
PY - Paraguay 13
CL - Cile 12
UZ - Uzbekistan 12
VE - Venezuela 12
UY - Uruguay 11
AE - Emirati Arabi Uniti 10
DZ - Algeria 10
EG - Egitto 10
IE - Irlanda 10
SA - Arabia Saudita 10
AU - Australia 9
AZ - Azerbaigian 9
KZ - Kazakistan 9
EU - Europa 8
KE - Kenya 8
TN - Tunisia 7
JO - Giordania 6
OM - Oman 6
AL - Albania 5
BG - Bulgaria 5
CR - Costa Rica 5
IL - Israele 5
IR - Iran 5
JM - Giamaica 5
NP - Nepal 5
PA - Panama 5
BO - Bolivia 4
BY - Bielorussia 4
GE - Georgia 4
HU - Ungheria 4
KG - Kirghizistan 4
ML - Mali 4
AO - Angola 3
BH - Bahrain 3
DO - Repubblica Dominicana 3
EE - Estonia 3
ET - Etiopia 3
LT - Lituania 3
MD - Moldavia 3
NG - Nigeria 3
RS - Serbia 3
CG - Congo 2
GA - Gabon 2
KH - Cambogia 2
LA - Repubblica Popolare Democratica del Laos 2
LK - Sri Lanka 2
LV - Lettonia 2
MU - Mauritius 2
PH - Filippine 2
QA - Qatar 2
RO - Romania 2
TH - Thailandia 2
TT - Trinidad e Tobago 2
AM - Armenia 1
BN - Brunei Darussalam 1
BW - Botswana 1
CH - Svizzera 1
CY - Cipro 1
GD - Grenada 1
GT - Guatemala 1
HN - Honduras 1
HR - Croazia 1
KW - Kuwait 1
Totale 15.106
Città #
Moscow 2.387
Dallas 894
Singapore 683
Chandler 636
Jacksonville 384
Boardman 293
San Mateo 269
Vienna 230
Beijing 221
Ashburn 216
Dearborn 202
New York 191
Ho Chi Minh City 174
Dakar 162
Hong Kong 120
Seoul 111
Hanoi 110
Helsinki 108
Lawrence 102
Rende 100
Roxbury 99
Munich 97
Shanghai 97
Hefei 82
Izmir 77
Brooklyn 71
São Paulo 70
Des Moines 66
Florence 62
Los Angeles 57
Ann Arbor 47
Ottawa 41
The Dalles 38
Seattle 36
Wilmington 34
Columbus 33
Inglewood 32
Ogden 32
Brussels 31
Bremen 27
San Francisco 27
Brno 26
Tokyo 25
Turku 25
Biên Hòa 20
Guayaquil 20
Haiphong 20
Cosenza 19
Frankfurt am Main 18
Houston 18
Warsaw 18
Bari 17
Catanzaro 17
Council Bluffs 17
Guangzhou 17
Naples 17
Cambridge 16
Santa Clara 16
Jakarta 15
Rio de Janeiro 15
Stockholm 15
Amsterdam 14
Brasília 14
Chennai 14
Chicago 14
Da Nang 14
Dhaka 14
Falkenstein 14
Redmond 14
Redwood City 14
Toronto 14
Baghdad 13
Buenos Aires 13
Johannesburg 13
Pune 13
Tianjin 13
Arcavacata 12
Mexico City 12
Quito 12
Belo Horizonte 11
Grafing 11
London 11
Montevideo 11
Ninh Bình 11
Phoenix 10
Quảng Ngãi 10
Tashkent 10
Wuhan 10
Amantea 9
Dublin 9
Fortaleza 9
Guarulhos 9
Lima 9
Montreal 9
Rome 9
Shenzhen 9
Baku 8
Falls Church 8
Kilburn 8
Lahore 8
Totale 9.560
Nome #
c-Jun activation is required for 4-hydroxytamoxifen-induced cell death in breast cancer cells 2.528
Crystallographic snapshots of host–guest interactions in drugs@metal–organic frameworks: towards mimicking molecular recognition processes 212
(6-Bromo-1,4-dimethyl-9H-carbazol-3-yl-methylene)-hydrazine (Carbhydraz) Acts as a GPER Agonist in Breast Cancer Cells 201
AHR and GPER mediate the stimulatory effects induced by 3-methylcholanthrene in breast cancer cells and cancer-associated fibroblasts (CAFs) 191
A calixpyrrole derivative acts as an antagonist to GPER, a G-protein coupled receptor: mechanisms and models. 182
Focal adhesion kinase (FAK) activation by estrogens involves GPER in triple-negative breast cancer cells 180
Copper activates HIF-1α/GPER/VEGF signalling in cancer cells 177
GPER Mediates a Feedforward FGF2/FGFR1 Paracrine Activation Coupling CAFs to Cancer Cells Toward Breast Tumor Progression 177
Functional characterization of the partially purified Sac1p-independent adenine nucleotide transport system (ANTS) from yeast endoplasmic reticulum 176
Computational Approaches for the Discovery of GPER Targeting Compounds 176
Bisphenol A Induces Gene Expression Changes and Proliferative Effects through GPER in Breast Cancer Cells and Cancer-Associated Fibroblasts 173
E-cadherin mediates the aggregation of breast cancer cells induced by tamoxifen and epidermal growth factor 162
GPER, IGF-IR, and EGFR transduction signaling are involved in stimulatory effects of zinc in breast cancer cells and cancer-associated fibroblasts 160
A Biocompatible Aspartic-Decorated Metal-Organic Framework with Tubular Motif Degradable under Physiological Conditions 160
Carbazole derivatives as potential novel agonist of GPER 152
miR-338-3p Is Regulated by Estrogens through GPER in Breast Cancer Cells and Cancer-Associated Fibroblasts (CAFs) 148
Epidermal growth factor induces G protein-coupled receptor 30 expression in estrogen receptor-negative breast cancer cells 146
Activation of the s100a7/rage pathway by igf-1 contributes to angiogenesis in breast cancer 143
A sexually dimorphic distribution pattern of the novel estrogen receptor G-protein coupled receptor 30 in some brain areas of the hamster 138
Interleukin-1β mediates a tumor-supporting environment prompted by IGF1 in triple-negative breast cancer (TNBC) 138
Composition, Antifungal and Antiproliferative Activities of the Hydrodistilled Oils from Leaves and Flower Heads of Pterocephalus nestorianus Nab. 137
GPER is involved in the stimulatory effects of aldosterone in breast cancer cells and breast tumor-derived endothelial cells 137
Identification of novel estrogen-regulated microRNAs in breast tumor cells and cancer-associated fibroblasts (CAFS) 137
A Bodipy as a luminescent probe for detection of the G protein estrogen receptor (GPER) 136
Cancer associated fibroblasts: role in breast cancer and potential as therapeutic targets 136
DDR1 regulates thyroid cancer cell differentiation via IGF-2/IR-A autocrine signaling loop 134
G protein-coupled estrogen receptor mediates the up-regulation of fatty acid synthase induced by 17β-estradiol in cancer cells and cancer-associated fibroblasts 133
Focal Adhesion Kinase Fine Tunes Multifaced Signals toward Breast Cancer Progression 130
The G Protein-Coupled Estrogen Receptor (GPER) Expression Correlates with Pro-Metastatic Pathways in ER-Negative Breast Cancer: A Bioinformatics Analysis 129
Focal Adhesion Kinase (FAK)-Hippo/YAP transduction signaling mediates the stimulatory effects exerted by S100A8/A9-RAGE system in triple-negative breast cancer (TNBC) 127
In vitro antiproliferative and proapoptotic activities of 2-oxazolidinone derivatives 127
Effects of antidiabetic medications on the relationship between type 2 diabetes mellitus and cognitive impairment 127
IGF-1/IGF-1R/FAK/YAP Transduction Signaling Prompts Growth Effects in Triple-Negative Breast Cancer (TNBC) Cells 126
The IL1β-IL1R signaling is involved in the stimulatory effects triggered by hypoxia in breast cancer cells and cancer-associated fibroblasts (CAFs) 124
Estrogenic Gper-signaling triggers RERG expression in breast cancer cells and cancer-associated fibroblasts 123
G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17beta-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells 123
GPER mediates activation of HIF1α/VEGF signaling by estrogens 121
HIF-1α/GPER signaling mediates the expression of VEGF induced by hypoxia in breast cancer associated fibroblasts (CAFs) 121
The lauric acid-activated signaling prompts apoptosis in cancer cells 119
HYPOXIA PROMOTES TUBULAR INJURY VIA THE ACTIVATION OF THE ESTROGENIC RECEPTOR GPER AND P75(NTR) 119
Estrogen receptor variant ERα46 and insulin receptor drive in primary breast cancer cells growth effects and interleukin 11 induction prompting the motility of cancer‐associated fibroblasts 118
Epidermal growth factor up-regulates SLC37A1 gene expression in cancer cells. 117
Metformin counteracts stimulatory effects induced by insulin in primary breast cancer cells 116
The Ephrin tyrosine kinase a3 (EphA3) is a novel mediator of RAGE-prompted motility of breast cancer cells 116
Different 6-Aryl-Fulvenes exert anti-proliferative effects on Cancer Cells 115
GPER is involved in the regulation of the estrogen-metabolizing CYP1B1 enzyme in breast cancer 113
Glycerophospholipid synthesis as a novel drug target against cancer 112
A Review on the Antimicrobial Activity of Schiff Bases: Data Collection and Recent Studies 112
miR-221 stimulates breast cancer cells and cancer-associated fibroblasts (CAFs) through selective interference with the A20/c-Rel/CTGF signaling 111
Newly Synthesized Imino-Derivatives Analogues of Resveratrol Exert Inhibitory Effects in Breast Tumor Cells 111
A novel functional crosstalk between DDR1 and the IGF axis and its relevance for breast cancer 109
The Peptide ERα17p Is a GPER Inverse Agonist that Exerts Antiproliferative Effects in Breast Cancer Cells 109
SIRT1 is involved in oncogenic signaling mediated by GPER in breast cancer 107
GPCR modulation in breast cancer 106
SLC37A1 Gene expression is up-regulated by epidermal growth factor in breast cancer cells 105
GPER signalling in both cancer-associated fibroblasts and breast cancer cells mediates a feedforward IL1β/IL1R1 response 105
G protein-coupled receptor 30 expression is up-regulated by EGF and TGFalpha in estrogen receptor alpha-positive cancer cells 105
Estriol acts as a GPR30 antagonist in estrogen receptor-negative breast cancer cells 104
GPER deletion triggers inhibitory effects in triple negative breast cancer (TNBC) cells through the JNK/c-Jun/p53/Noxa transduction pathway 103
Recent Advances on the Role of G Protein-Coupled Receptors in Hypoxia-Mediated Signaling 103
Cross-talk between GPER and growth factor signaling 103
MIBE acts as antagonist ligand of both estrogen receptor alpha and GPER in breast cancer cells 102
The G Protein Estrogen Receptor (GPER) is involved in the resistance to the CDK4/6 inhibitor palbociclib in breast cancer 101
Recent Advances in the Rationale Design of GPER Ligands. 101
Ddr1 affects metabolic reprogramming in breast cancer cells by cross-talking to the insulin/igf system 101
The AGEs/RAGE Transduction Signaling Prompts IL-8/CXCR1/2-Mediated Interaction between Cancer-Associated Fibroblasts (CAFs) and Breast Cancer Cells 101
GPCRs and cancer 100
Two Novel GPER Agonists Induce Gene Expression Changes and Growth Effects in Cancer Cells. 98
Insulin-like growth factor-I regulates GPER expression and function in cancer cells 92
Multifactorial Regulation of GPER Expression in Cancer Cells and Cardiomyocytes 92
IGF-I/IGF-IR Transduction System Involves GPER and DDR1 in the Stimulation of Mesothelioma and Lung Cancer Cells 92
GPER is involved in the regulation of CYP1b1 expression in breast cancer cells and CAFs 90
Novel Mechanisms Involved in the Stimulatory Effects Exerted by Zinc in Breast Cancer Cells 90
Cancer-associated fibroblasts (CAFs) gene signatures predict outcomes in breast and prostate tumor patients 89
Macromolecular Modelling and Docking Simulations for the Discovery of Selective GPER Ligands. 89
Stimulatory actions of IGF-I are mediated by IGF-IR cross-talk with GPER and DDR1 in mesothelioma and lung cancer cells 89
GPER Function in Breast Cancer: An Overview 87
Tamoxifen and epidermal growth factor induce the aggregation of MCF7 breast cancer cells up-regulating E-cadherin expression 87
Effects of Atrazine on Estrogen Receptor α- and G Protein-Coupled Receptor 30-Mediated Signaling and Proliferation in Cancer Cells and Cancer-Associated Fibroblasts 86
New titanocene derivatives with high antiproliferative activity against breast cancer cells 85
Niacin activates the G protein estrogen receptor (GPER)-mediated signalling 84
Recent views of heavy metals as possible risk factors and potential preventive and therapeutic agents in prostate cancer 83
RUOLO DEL RECETTORE p75NTR E DEL RECETTORE ESTROGENICO GPER NEL DANNO IPOSSICO TUBULARE 83
RAGE inhibition blunts insulin-induced oncogenic signals in breast cancer 82
Dissecting CYP1A2 Activation by Arylalkanoic Acid Prodrugs toward the Development of Anti-Inflammatory Agents 82
ESTROGENIC GPR30 SIGNALLING INDUCES PROLIFERATION AND MIGRATION OF BREAST CANCER CELLS THROUGH CTGF 82
The novel estrogen receptor GRP30 mediates the proliferatiive effects induced by 17beta-estradiol onGC-1 mouse spermatogonial cell line 81
Structure-activity relationships of resveratrol and derivatives in breast cancer cells 81
Organo-Metallic Compounds: Novel Molecules in Cancer Therapy 80
Interaction of the Anti-Proliferative GPER Inverse Agonist ERα17p with the Breast Cancer Cell Plasma Membrane: From Biophysics to Biology 80
Identification of a human estrogen receptor α tetrapeptidic fragment with dual antiproliferative and anti-nociceptive action 79
RUOLO DEL NUOVO RECETTORE ESTROGENICO GPER E DELL'ASSE NGF/TRKA/P75NTR NEL DANNO IPOSSICO TUBULARE RENALE 78
The Novel Estrogen Receptor GPR30 Mediates the Proliferative Effects Induced by 17beta-Estradiol on GC-1 Mouse Spermatogonial Cell Line 77
G protein-coupled receptors: novel targets for drug discovery in cancer 75
Regulation of SLC37A1 gene expression by epidermal growth factor in breast cancer cells 75
Synthesis, characterization and cytotoxic activity on breast cancer cells of new half-titanocene derivatives 75
Recent advances on the stimulatory effects of metals in breast cancer 73
The novel estrogen receptor, G protein-coupled receptor 30, mediates the proliferative effects induced by 17β-estradiol on mouse spermatogonial GC-1 cell line 73
Estetrol/GPER/SERPINB2 transduction signaling inhibits the motility of triple-negative breast cancer cells 72
The cholesterol metabolite 25-Hydroxycholesterol activates estrogen receptor α-Mediated signaling in cancer cells and in cardiomyocytes 72
Totale 13.925
Categoria #
all - tutte 79.470
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 79.470


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021426 0 0 0 0 0 90 20 121 37 88 5 65
2021/20221.296 6 221 12 85 135 31 14 306 16 16 166 288
2022/20231.703 211 218 76 232 178 139 9 242 172 45 115 66
2023/20242.407 153 69 80 30 55 367 432 426 99 200 162 334
2024/20253.441 554 509 355 318 113 135 119 181 382 146 241 388
2025/20264.534 818 319 1.263 583 1.178 373 0 0 0 0 0 0
Totale 15.353