LAPPANO, Rosamaria
 Distribuzione geografica
Continente #
NA - Nord America 6.144
EU - Europa 5.742
AS - Asia 4.755
SA - Sud America 1.283
AF - Africa 349
OC - Oceania 12
Continente sconosciuto - Info sul continente non disponibili 9
Totale 18.294
Nazione #
US - Stati Uniti d'America 5.922
RU - Federazione Russa 2.640
SG - Singapore 1.929
BR - Brasile 914
CN - Cina 913
VN - Vietnam 774
UA - Ucraina 736
IT - Italia 658
DE - Germania 513
AT - Austria 319
SE - Svezia 210
FR - Francia 181
BD - Bangladesh 179
SN - Senegal 166
HK - Hong Kong 161
FI - Finlandia 152
IN - India 137
AR - Argentina 129
TR - Turchia 124
KR - Corea 113
CA - Canada 108
GB - Regno Unito 88
ID - Indonesia 66
MX - Messico 64
NL - Olanda 62
EC - Ecuador 60
IQ - Iraq 59
ZA - Sudafrica 52
CO - Colombia 51
PK - Pakistan 46
BE - Belgio 34
VE - Venezuela 33
JP - Giappone 32
MA - Marocco 30
CZ - Repubblica Ceca 29
PL - Polonia 28
PY - Paraguay 28
CL - Cile 26
SA - Arabia Saudita 23
PH - Filippine 22
UZ - Uzbekistan 21
DZ - Algeria 20
ES - Italia 20
TN - Tunisia 18
AE - Emirati Arabi Uniti 17
UY - Uruguay 17
PE - Perù 16
KZ - Kazakistan 15
MY - Malesia 15
EG - Egitto 13
IE - Irlanda 13
KE - Kenya 13
AZ - Azerbaigian 12
AU - Australia 11
NP - Nepal 11
IL - Israele 10
JO - Giordania 10
CR - Costa Rica 9
ET - Etiopia 9
OM - Oman 9
AL - Albania 8
BO - Bolivia 8
EU - Europa 8
DO - Repubblica Dominicana 7
JM - Giamaica 7
KH - Cambogia 7
HU - Ungheria 6
BG - Bulgaria 5
GE - Georgia 5
IR - Iran 5
KG - Kirghizistan 5
LB - Libano 5
PA - Panama 5
RS - Serbia 5
AO - Angola 4
BH - Bahrain 4
BY - Bielorussia 4
EE - Estonia 4
GA - Gabon 4
LT - Lituania 4
ML - Mali 4
NG - Nigeria 4
QA - Qatar 4
TH - Thailandia 4
CG - Congo 3
CH - Svizzera 3
GT - Guatemala 3
HN - Honduras 3
KW - Kuwait 3
LK - Sri Lanka 3
MD - Moldavia 3
RO - Romania 3
SV - El Salvador 3
TT - Trinidad e Tobago 3
BW - Botswana 2
GD - Grenada 2
GR - Grecia 2
HR - Croazia 2
LA - Repubblica Popolare Democratica del Laos 2
LV - Lettonia 2
Totale 18.258
Città #
Moscow 2.601
Dallas 906
Singapore 786
Chandler 636
San Jose 507
Jacksonville 387
Ashburn 360
Boardman 294
Ho Chi Minh City 274
San Mateo 269
New York 258
Beijing 243
Vienna 232
Dearborn 202
Hanoi 184
Council Bluffs 168
Dakar 166
Hong Kong 150
Lauterbourg 113
Helsinki 112
Seoul 111
Rende 104
Lawrence 102
Shanghai 100
Roxbury 99
Munich 97
São Paulo 87
Hefei 82
Izmir 78
Los Angeles 78
Brooklyn 73
Des Moines 66
Florence 65
Ann Arbor 47
Ottawa 42
Columbus 41
The Dalles 38
Haiphong 37
Seattle 37
Santa Clara 34
Wilmington 34
Inglewood 32
Ogden 32
Brussels 31
Da Nang 31
San Francisco 28
Bremen 27
Tokyo 27
Brno 26
Biên Hòa 25
Turku 25
Frankfurt am Main 24
Guayaquil 24
Guangzhou 23
Naples 23
Orem 23
Baghdad 22
Warsaw 22
Chennai 21
Cosenza 21
Johannesburg 20
Rio de Janeiro 20
Toronto 20
Amsterdam 19
Brasília 19
Dhaka 19
Milan 19
Tashkent 19
Bari 18
Chicago 18
Houston 18
Jakarta 18
Buenos Aires 17
Catanzaro 17
Montevideo 17
Tianjin 17
Cambridge 16
Pune 16
Quito 16
Rome 16
Lahore 15
Mexico City 15
Stockholm 15
Falkenstein 14
Istanbul 14
London 14
Montreal 14
Ninh Bình 14
Redmond 14
Redwood City 14
Shenzhen 13
Arcavacata 12
Belo Horizonte 12
Bogotá 12
Buffalo 12
Dublin 12
Hải Dương 12
Asunción 11
Curitiba 11
Grafing 11
Totale 11.407
Nome #
c-Jun activation is required for 4-hydroxytamoxifen-induced cell death in breast cancer cells 2.802
Crystallographic snapshots of host–guest interactions in drugs@metal–organic frameworks: towards mimicking molecular recognition processes 257
(6-Bromo-1,4-dimethyl-9H-carbazol-3-yl-methylene)-hydrazine (Carbhydraz) Acts as a GPER Agonist in Breast Cancer Cells 232
AHR and GPER mediate the stimulatory effects induced by 3-methylcholanthrene in breast cancer cells and cancer-associated fibroblasts (CAFs) 229
Focal adhesion kinase (FAK) activation by estrogens involves GPER in triple-negative breast cancer cells 223
Computational Approaches for the Discovery of GPER Targeting Compounds 221
A calixpyrrole derivative acts as an antagonist to GPER, a G-protein coupled receptor: mechanisms and models. 218
Functional characterization of the partially purified Sac1p-independent adenine nucleotide transport system (ANTS) from yeast endoplasmic reticulum 217
Copper activates HIF-1α/GPER/VEGF signalling in cancer cells 211
GPER Mediates a Feedforward FGF2/FGFR1 Paracrine Activation Coupling CAFs to Cancer Cells Toward Breast Tumor Progression 205
GPER, IGF-IR, and EGFR transduction signaling are involved in stimulatory effects of zinc in breast cancer cells and cancer-associated fibroblasts 200
A Biocompatible Aspartic-Decorated Metal-Organic Framework with Tubular Motif Degradable under Physiological Conditions 195
Bisphenol A Induces Gene Expression Changes and Proliferative Effects through GPER in Breast Cancer Cells and Cancer-Associated Fibroblasts 194
E-cadherin mediates the aggregation of breast cancer cells induced by tamoxifen and epidermal growth factor 190
Carbazole derivatives as potential novel agonist of GPER 186
miR-338-3p Is Regulated by Estrogens through GPER in Breast Cancer Cells and Cancer-Associated Fibroblasts (CAFs) 183
G protein-coupled estrogen receptor mediates the up-regulation of fatty acid synthase induced by 17β-estradiol in cancer cells and cancer-associated fibroblasts 182
Metformin counteracts stimulatory effects induced by insulin in primary breast cancer cells 181
Epidermal growth factor induces G protein-coupled receptor 30 expression in estrogen receptor-negative breast cancer cells 176
Focal Adhesion Kinase Fine Tunes Multifaced Signals toward Breast Cancer Progression 176
Interleukin-1β mediates a tumor-supporting environment prompted by IGF1 in triple-negative breast cancer (TNBC) 168
Focal Adhesion Kinase (FAK)-Hippo/YAP transduction signaling mediates the stimulatory effects exerted by S100A8/A9-RAGE system in triple-negative breast cancer (TNBC) 166
DDR1 regulates thyroid cancer cell differentiation via IGF-2/IR-A autocrine signaling loop 163
Cancer associated fibroblasts: role in breast cancer and potential as therapeutic targets 163
The lauric acid-activated signaling prompts apoptosis in cancer cells 162
Activation of the s100a7/rage pathway by igf-1 contributes to angiogenesis in breast cancer 161
GPER is involved in the stimulatory effects of aldosterone in breast cancer cells and breast tumor-derived endothelial cells 158
A sexually dimorphic distribution pattern of the novel estrogen receptor G-protein coupled receptor 30 in some brain areas of the hamster 157
The Ephrin tyrosine kinase a3 (EphA3) is a novel mediator of RAGE-prompted motility of breast cancer cells 156
A Bodipy as a luminescent probe for detection of the G protein estrogen receptor (GPER) 156
Composition, Antifungal and Antiproliferative Activities of the Hydrodistilled Oils from Leaves and Flower Heads of Pterocephalus nestorianus Nab. 154
Identification of novel estrogen-regulated microRNAs in breast tumor cells and cancer-associated fibroblasts (CAFS) 153
Estrogenic Gper-signaling triggers RERG expression in breast cancer cells and cancer-associated fibroblasts 153
In vitro antiproliferative and proapoptotic activities of 2-oxazolidinone derivatives 153
IGF-1/IGF-1R/FAK/YAP Transduction Signaling Prompts Growth Effects in Triple-Negative Breast Cancer (TNBC) Cells 150
The G Protein-Coupled Estrogen Receptor (GPER) Expression Correlates with Pro-Metastatic Pathways in ER-Negative Breast Cancer: A Bioinformatics Analysis 147
G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17beta-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells 145
Different 6-Aryl-Fulvenes exert anti-proliferative effects on Cancer Cells 143
Estrogen receptor variant ERα46 and insulin receptor drive in primary breast cancer cells growth effects and interleukin 11 induction prompting the motility of cancer‐associated fibroblasts 143
A Review on the Antimicrobial Activity of Schiff Bases: Data Collection and Recent Studies 143
GPER mediates activation of HIF1α/VEGF signaling by estrogens 142
The IL1β-IL1R signaling is involved in the stimulatory effects triggered by hypoxia in breast cancer cells and cancer-associated fibroblasts (CAFs) 142
HYPOXIA PROMOTES TUBULAR INJURY VIA THE ACTIVATION OF THE ESTROGENIC RECEPTOR GPER AND P75(NTR) 142
Cancer-associated fibroblasts (CAFs) gene signatures predict outcomes in breast and prostate tumor patients 141
Effects of antidiabetic medications on the relationship between type 2 diabetes mellitus and cognitive impairment 141
Estriol acts as a GPR30 antagonist in estrogen receptor-negative breast cancer cells 138
GPER is involved in the regulation of the estrogen-metabolizing CYP1B1 enzyme in breast cancer 137
The G Protein Estrogen Receptor (GPER) is involved in the resistance to the CDK4/6 inhibitor palbociclib in breast cancer 136
HIF-1α/GPER signaling mediates the expression of VEGF induced by hypoxia in breast cancer associated fibroblasts (CAFs) 136
G protein-coupled receptor 30 expression is up-regulated by EGF and TGFalpha in estrogen receptor alpha-positive cancer cells 136
SLC37A1 Gene expression is up-regulated by epidermal growth factor in breast cancer cells 134
GPER deletion triggers inhibitory effects in triple negative breast cancer (TNBC) cells through the JNK/c-Jun/p53/Noxa transduction pathway 133
The Peptide ERα17p Is a GPER Inverse Agonist that Exerts Antiproliferative Effects in Breast Cancer Cells 132
Newly Synthesized Imino-Derivatives Analogues of Resveratrol Exert Inhibitory Effects in Breast Tumor Cells 132
SIRT1 is involved in oncogenic signaling mediated by GPER in breast cancer 131
Epidermal growth factor up-regulates SLC37A1 gene expression in cancer cells. 128
GPER signalling in both cancer-associated fibroblasts and breast cancer cells mediates a feedforward IL1β/IL1R1 response 128
A novel functional crosstalk between DDR1 and the IGF axis and its relevance for breast cancer 128
Recent Advances on the Role of G Protein-Coupled Receptors in Hypoxia-Mediated Signaling 127
Effects of Atrazine on Estrogen Receptor α- and G Protein-Coupled Receptor 30-Mediated Signaling and Proliferation in Cancer Cells and Cancer-Associated Fibroblasts 124
miR-221 stimulates breast cancer cells and cancer-associated fibroblasts (CAFs) through selective interference with the A20/c-Rel/CTGF signaling 124
The AGEs/RAGE Transduction Signaling Prompts IL-8/CXCR1/2-Mediated Interaction between Cancer-Associated Fibroblasts (CAFs) and Breast Cancer Cells 123
MIBE acts as antagonist ligand of both estrogen receptor alpha and GPER in breast cancer cells 122
Glycerophospholipid synthesis as a novel drug target against cancer 120
Cross-talk between GPER and growth factor signaling 118
Two Novel GPER Agonists Induce Gene Expression Changes and Growth Effects in Cancer Cells. 116
Ddr1 affects metabolic reprogramming in breast cancer cells by cross-talking to the insulin/igf system 116
GPCR modulation in breast cancer 115
Stimulatory actions of IGF-I are mediated by IGF-IR cross-talk with GPER and DDR1 in mesothelioma and lung cancer cells 113
GPCRs and cancer 112
Insulin-like growth factor-I regulates GPER expression and function in cancer cells 111
Estetrol/GPER/SERPINB2 transduction signaling inhibits the motility of triple-negative breast cancer cells 109
Recent Advances in the Rationale Design of GPER Ligands. 109
GPER is involved in the regulation of CYP1b1 expression in breast cancer cells and CAFs 107
Dissecting CYP1A2 Activation by Arylalkanoic Acid Prodrugs toward the Development of Anti-Inflammatory Agents 106
Macromolecular Modelling and Docking Simulations for the Discovery of Selective GPER Ligands. 104
New titanocene derivatives with high antiproliferative activity against breast cancer cells 104
ESTROGENIC GPR30 SIGNALLING INDUCES PROLIFERATION AND MIGRATION OF BREAST CANCER CELLS THROUGH CTGF 104
Niacin activates the G protein estrogen receptor (GPER)-mediated signalling 103
The novel estrogen receptor, G protein-coupled receptor 30, mediates the proliferative effects induced by 17β-estradiol on mouse spermatogonial GC-1 cell line 103
Multifactorial Regulation of GPER Expression in Cancer Cells and Cardiomyocytes 102
IGF-I/IGF-IR Transduction System Involves GPER and DDR1 in the Stimulation of Mesothelioma and Lung Cancer Cells 102
Tamoxifen and epidermal growth factor induce the aggregation of MCF7 breast cancer cells up-regulating E-cadherin expression 102
RAGE inhibition blunts insulin-induced oncogenic signals in breast cancer 101
GPER Function in Breast Cancer: An Overview 100
RUOLO DEL RECETTORE p75NTR E DEL RECETTORE ESTROGENICO GPER NEL DANNO IPOSSICO TUBULARE 100
Identification of a human estrogen receptor α tetrapeptidic fragment with dual antiproliferative and anti-nociceptive action 99
Structure-activity relationships of resveratrol and derivatives in breast cancer cells 99
Novel Mechanisms Involved in the Stimulatory Effects Exerted by Zinc in Breast Cancer Cells 98
The novel estrogen receptor GRP30 mediates the proliferatiive effects induced by 17beta-estradiol onGC-1 mouse spermatogonial cell line 95
RUOLO DEL NUOVO RECETTORE ESTROGENICO GPER E DELL'ASSE NGF/TRKA/P75NTR NEL DANNO IPOSSICO TUBULARE RENALE 94
Recent views of heavy metals as possible risk factors and potential preventive and therapeutic agents in prostate cancer 93
Regulation of SLC37A1 gene expression by epidermal growth factor in breast cancer cells 92
Organo-Metallic Compounds: Novel Molecules in Cancer Therapy 91
The Novel Estrogen Receptor GPR30 Mediates the Proliferative Effects Induced by 17beta-Estradiol on GC-1 Mouse Spermatogonial Cell Line 91
The Physiopathological Role of the Exchangers Belonging to the SLC37 Family 91
Harnessing sample preparation for RNA-sequencing toward a reliable bioinformatics analysis 89
Interaction of the Anti-Proliferative GPER Inverse Agonist ERα17p with the Breast Cancer Cell Plasma Membrane: From Biophysics to Biology 89
New metallorganic complexes of groups 3 and 4 as anticancer agents: Possible alterative to cis-platin. 88
Synthesis, characterization and cytotoxic activity on breast cancer cells of new half-titanocene derivatives 88
Totale 16.603
Categoria #
all - tutte 87.770
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 87.770


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202165 0 0 0 0 0 0 0 0 0 0 0 65
2021/20221.296 6 221 12 85 135 31 14 306 16 16 166 288
2022/20231.703 211 218 76 232 178 139 9 242 172 45 115 66
2023/20242.407 153 69 80 30 55 367 432 426 99 200 162 334
2024/20253.441 554 509 355 318 113 135 119 181 382 146 241 388
2025/20267.711 818 319 1.263 583 1.178 522 760 492 582 543 338 313
Totale 18.530