LAPPANO, Rosamaria
 Distribuzione geografica
Continente #
NA - Nord America 5.696
EU - Europa 5.645
AS - Asia 4.597
SA - Sud America 1.281
AF - Africa 349
OC - Oceania 11
Continente sconosciuto - Info sul continente non disponibili 9
Totale 17.588
Nazione #
US - Stati Uniti d'America 5.496
RU - Federazione Russa 2.640
SG - Singapore 1.909
BR - Brasile 912
CN - Cina 877
VN - Vietnam 770
UA - Ucraina 736
IT - Italia 565
DE - Germania 513
AT - Austria 319
SE - Svezia 210
FR - Francia 181
SN - Senegal 166
HK - Hong Kong 158
FI - Finlandia 152
IN - India 136
AR - Argentina 129
TR - Turchia 124
KR - Corea 113
CA - Canada 97
BD - Bangladesh 91
GB - Regno Unito 85
ID - Indonesia 65
MX - Messico 63
NL - Olanda 61
EC - Ecuador 60
IQ - Iraq 59
ZA - Sudafrica 52
CO - Colombia 51
PK - Pakistan 46
BE - Belgio 34
VE - Venezuela 33
JP - Giappone 30
MA - Marocco 30
CZ - Repubblica Ceca 29
PL - Polonia 28
PY - Paraguay 28
CL - Cile 26
SA - Arabia Saudita 23
PH - Filippine 22
UZ - Uzbekistan 21
DZ - Algeria 20
ES - Italia 20
TN - Tunisia 18
AE - Emirati Arabi Uniti 17
UY - Uruguay 17
PE - Perù 16
KZ - Kazakistan 15
MY - Malesia 14
EG - Egitto 13
IE - Irlanda 13
KE - Kenya 13
AZ - Azerbaigian 12
AU - Australia 11
NP - Nepal 11
IL - Israele 10
JO - Giordania 10
ET - Etiopia 9
OM - Oman 9
AL - Albania 8
BO - Bolivia 8
EU - Europa 8
DO - Repubblica Dominicana 7
KH - Cambogia 7
HU - Ungheria 6
JM - Giamaica 6
BG - Bulgaria 5
CR - Costa Rica 5
GE - Georgia 5
IR - Iran 5
KG - Kirghizistan 5
LB - Libano 5
PA - Panama 5
RS - Serbia 5
AO - Angola 4
BH - Bahrain 4
BY - Bielorussia 4
EE - Estonia 4
GA - Gabon 4
LT - Lituania 4
ML - Mali 4
NG - Nigeria 4
QA - Qatar 4
CG - Congo 3
CH - Svizzera 3
GT - Guatemala 3
KW - Kuwait 3
LK - Sri Lanka 3
MD - Moldavia 3
RO - Romania 3
TH - Thailandia 3
BW - Botswana 2
GD - Grenada 2
GR - Grecia 2
HR - Croazia 2
LA - Repubblica Popolare Democratica del Laos 2
LV - Lettonia 2
MU - Mauritius 2
PR - Porto Rico 2
PS - Palestinian Territory 2
Totale 17.556
Città #
Moscow 2.601
Dallas 896
Singapore 782
Chandler 636
San Jose 457
Jacksonville 384
Ashburn 329
Boardman 294
Ho Chi Minh City 274
San Mateo 269
Beijing 238
Vienna 232
Dearborn 202
New York 200
Hanoi 183
Dakar 166
Hong Kong 147
Lauterbourg 113
Helsinki 112
Seoul 111
Rende 104
Lawrence 102
Shanghai 100
Roxbury 99
Munich 97
São Paulo 87
Hefei 82
Izmir 78
Los Angeles 74
Brooklyn 71
Des Moines 66
Florence 63
Ann Arbor 47
Ottawa 41
The Dalles 38
Haiphong 37
Seattle 36
Wilmington 34
Columbus 33
Inglewood 32
Ogden 32
Brussels 31
Da Nang 31
Bremen 27
San Francisco 27
Tokyo 27
Brno 26
Biên Hòa 25
Turku 25
Frankfurt am Main 24
Guayaquil 24
Santa Clara 24
Orem 23
Baghdad 22
Guangzhou 22
Warsaw 22
Chennai 21
Council Bluffs 20
Johannesburg 20
Amsterdam 19
Brasília 19
Cosenza 19
Dhaka 19
Rio de Janeiro 19
Tashkent 19
Houston 18
Jakarta 18
Toronto 18
Bari 17
Buenos Aires 17
Catanzaro 17
Montevideo 17
Naples 17
Tianjin 17
Cambridge 16
Pune 16
Quito 16
Chicago 15
Lahore 15
Stockholm 15
Falkenstein 14
Istanbul 14
London 14
Mexico City 14
Ninh Bình 14
Redmond 14
Redwood City 14
Shenzhen 13
Arcavacata 12
Belo Horizonte 12
Bogotá 12
Dublin 12
Hải Dương 12
Montreal 12
Asunción 11
Curitiba 11
Grafing 11
Nairobi 11
Quảng Ngãi 11
Salvador 11
Totale 11.032
Nome #
c-Jun activation is required for 4-hydroxytamoxifen-induced cell death in breast cancer cells 2.774
Crystallographic snapshots of host–guest interactions in drugs@metal–organic frameworks: towards mimicking molecular recognition processes 250
(6-Bromo-1,4-dimethyl-9H-carbazol-3-yl-methylene)-hydrazine (Carbhydraz) Acts as a GPER Agonist in Breast Cancer Cells 228
AHR and GPER mediate the stimulatory effects induced by 3-methylcholanthrene in breast cancer cells and cancer-associated fibroblasts (CAFs) 216
Computational Approaches for the Discovery of GPER Targeting Compounds 212
A calixpyrrole derivative acts as an antagonist to GPER, a G-protein coupled receptor: mechanisms and models. 208
Copper activates HIF-1α/GPER/VEGF signalling in cancer cells 207
Focal adhesion kinase (FAK) activation by estrogens involves GPER in triple-negative breast cancer cells 201
Functional characterization of the partially purified Sac1p-independent adenine nucleotide transport system (ANTS) from yeast endoplasmic reticulum 200
GPER Mediates a Feedforward FGF2/FGFR1 Paracrine Activation Coupling CAFs to Cancer Cells Toward Breast Tumor Progression 198
Bisphenol A Induces Gene Expression Changes and Proliferative Effects through GPER in Breast Cancer Cells and Cancer-Associated Fibroblasts 194
A Biocompatible Aspartic-Decorated Metal-Organic Framework with Tubular Motif Degradable under Physiological Conditions 191
E-cadherin mediates the aggregation of breast cancer cells induced by tamoxifen and epidermal growth factor 185
GPER, IGF-IR, and EGFR transduction signaling are involved in stimulatory effects of zinc in breast cancer cells and cancer-associated fibroblasts 183
miR-338-3p Is Regulated by Estrogens through GPER in Breast Cancer Cells and Cancer-Associated Fibroblasts (CAFs) 180
Carbazole derivatives as potential novel agonist of GPER 176
Epidermal growth factor induces G protein-coupled receptor 30 expression in estrogen receptor-negative breast cancer cells 171
Interleukin-1β mediates a tumor-supporting environment prompted by IGF1 in triple-negative breast cancer (TNBC) 166
Activation of the s100a7/rage pathway by igf-1 contributes to angiogenesis in breast cancer 161
DDR1 regulates thyroid cancer cell differentiation via IGF-2/IR-A autocrine signaling loop 160
Cancer associated fibroblasts: role in breast cancer and potential as therapeutic targets 158
G protein-coupled estrogen receptor mediates the up-regulation of fatty acid synthase induced by 17β-estradiol in cancer cells and cancer-associated fibroblasts 156
A sexually dimorphic distribution pattern of the novel estrogen receptor G-protein coupled receptor 30 in some brain areas of the hamster 156
Focal Adhesion Kinase Fine Tunes Multifaced Signals toward Breast Cancer Progression 156
GPER is involved in the stimulatory effects of aldosterone in breast cancer cells and breast tumor-derived endothelial cells 155
Composition, Antifungal and Antiproliferative Activities of the Hydrodistilled Oils from Leaves and Flower Heads of Pterocephalus nestorianus Nab. 152
Identification of novel estrogen-regulated microRNAs in breast tumor cells and cancer-associated fibroblasts (CAFS) 152
A Bodipy as a luminescent probe for detection of the G protein estrogen receptor (GPER) 152
Focal Adhesion Kinase (FAK)-Hippo/YAP transduction signaling mediates the stimulatory effects exerted by S100A8/A9-RAGE system in triple-negative breast cancer (TNBC) 149
In vitro antiproliferative and proapoptotic activities of 2-oxazolidinone derivatives 149
Metformin counteracts stimulatory effects induced by insulin in primary breast cancer cells 148
Estrogenic Gper-signaling triggers RERG expression in breast cancer cells and cancer-associated fibroblasts 148
IGF-1/IGF-1R/FAK/YAP Transduction Signaling Prompts Growth Effects in Triple-Negative Breast Cancer (TNBC) Cells 148
The lauric acid-activated signaling prompts apoptosis in cancer cells 145
The G Protein-Coupled Estrogen Receptor (GPER) Expression Correlates with Pro-Metastatic Pathways in ER-Negative Breast Cancer: A Bioinformatics Analysis 142
The IL1β-IL1R signaling is involved in the stimulatory effects triggered by hypoxia in breast cancer cells and cancer-associated fibroblasts (CAFs) 141
Different 6-Aryl-Fulvenes exert anti-proliferative effects on Cancer Cells 140
GPER mediates activation of HIF1α/VEGF signaling by estrogens 140
Estrogen receptor variant ERα46 and insulin receptor drive in primary breast cancer cells growth effects and interleukin 11 induction prompting the motility of cancer‐associated fibroblasts 140
HYPOXIA PROMOTES TUBULAR INJURY VIA THE ACTIVATION OF THE ESTROGENIC RECEPTOR GPER AND P75(NTR) 139
Effects of antidiabetic medications on the relationship between type 2 diabetes mellitus and cognitive impairment 139
G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17beta-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells 138
The Ephrin tyrosine kinase a3 (EphA3) is a novel mediator of RAGE-prompted motility of breast cancer cells 136
A Review on the Antimicrobial Activity of Schiff Bases: Data Collection and Recent Studies 136
HIF-1α/GPER signaling mediates the expression of VEGF induced by hypoxia in breast cancer associated fibroblasts (CAFs) 135
GPER is involved in the regulation of the estrogen-metabolizing CYP1B1 enzyme in breast cancer 134
SLC37A1 Gene expression is up-regulated by epidermal growth factor in breast cancer cells 130
SIRT1 is involved in oncogenic signaling mediated by GPER in breast cancer 130
The Peptide ERα17p Is a GPER Inverse Agonist that Exerts Antiproliferative Effects in Breast Cancer Cells 130
Newly Synthesized Imino-Derivatives Analogues of Resveratrol Exert Inhibitory Effects in Breast Tumor Cells 129
The G Protein Estrogen Receptor (GPER) is involved in the resistance to the CDK4/6 inhibitor palbociclib in breast cancer 128
Epidermal growth factor up-regulates SLC37A1 gene expression in cancer cells. 127
GPER deletion triggers inhibitory effects in triple negative breast cancer (TNBC) cells through the JNK/c-Jun/p53/Noxa transduction pathway 126
Cancer-associated fibroblasts (CAFs) gene signatures predict outcomes in breast and prostate tumor patients 126
GPER signalling in both cancer-associated fibroblasts and breast cancer cells mediates a feedforward IL1β/IL1R1 response 125
Recent Advances on the Role of G Protein-Coupled Receptors in Hypoxia-Mediated Signaling 124
miR-221 stimulates breast cancer cells and cancer-associated fibroblasts (CAFs) through selective interference with the A20/c-Rel/CTGF signaling 124
A novel functional crosstalk between DDR1 and the IGF axis and its relevance for breast cancer 123
Estriol acts as a GPR30 antagonist in estrogen receptor-negative breast cancer cells 122
Effects of Atrazine on Estrogen Receptor α- and G Protein-Coupled Receptor 30-Mediated Signaling and Proliferation in Cancer Cells and Cancer-Associated Fibroblasts 121
MIBE acts as antagonist ligand of both estrogen receptor alpha and GPER in breast cancer cells 120
Glycerophospholipid synthesis as a novel drug target against cancer 120
G protein-coupled receptor 30 expression is up-regulated by EGF and TGFalpha in estrogen receptor alpha-positive cancer cells 119
The AGEs/RAGE Transduction Signaling Prompts IL-8/CXCR1/2-Mediated Interaction between Cancer-Associated Fibroblasts (CAFs) and Breast Cancer Cells 117
Ddr1 affects metabolic reprogramming in breast cancer cells by cross-talking to the insulin/igf system 115
Two Novel GPER Agonists Induce Gene Expression Changes and Growth Effects in Cancer Cells. 114
GPCR modulation in breast cancer 114
Cross-talk between GPER and growth factor signaling 113
GPCRs and cancer 110
Insulin-like growth factor-I regulates GPER expression and function in cancer cells 109
Recent Advances in the Rationale Design of GPER Ligands. 107
GPER is involved in the regulation of CYP1b1 expression in breast cancer cells and CAFs 107
Stimulatory actions of IGF-I are mediated by IGF-IR cross-talk with GPER and DDR1 in mesothelioma and lung cancer cells 107
New titanocene derivatives with high antiproliferative activity against breast cancer cells 103
Multifactorial Regulation of GPER Expression in Cancer Cells and Cardiomyocytes 102
RAGE inhibition blunts insulin-induced oncogenic signals in breast cancer 100
Macromolecular Modelling and Docking Simulations for the Discovery of Selective GPER Ligands. 100
IGF-I/IGF-IR Transduction System Involves GPER and DDR1 in the Stimulation of Mesothelioma and Lung Cancer Cells 99
Niacin activates the G protein estrogen receptor (GPER)-mediated signalling 99
Tamoxifen and epidermal growth factor induce the aggregation of MCF7 breast cancer cells up-regulating E-cadherin expression 99
ESTROGENIC GPR30 SIGNALLING INDUCES PROLIFERATION AND MIGRATION OF BREAST CANCER CELLS THROUGH CTGF 99
Identification of a human estrogen receptor α tetrapeptidic fragment with dual antiproliferative and anti-nociceptive action 97
GPER Function in Breast Cancer: An Overview 97
Novel Mechanisms Involved in the Stimulatory Effects Exerted by Zinc in Breast Cancer Cells 97
RUOLO DEL RECETTORE p75NTR E DEL RECETTORE ESTROGENICO GPER NEL DANNO IPOSSICO TUBULARE 96
Dissecting CYP1A2 Activation by Arylalkanoic Acid Prodrugs toward the Development of Anti-Inflammatory Agents 94
The novel estrogen receptor GRP30 mediates the proliferatiive effects induced by 17beta-estradiol onGC-1 mouse spermatogonial cell line 94
Recent views of heavy metals as possible risk factors and potential preventive and therapeutic agents in prostate cancer 93
RUOLO DEL NUOVO RECETTORE ESTROGENICO GPER E DELL'ASSE NGF/TRKA/P75NTR NEL DANNO IPOSSICO TUBULARE RENALE 93
Structure-activity relationships of resveratrol and derivatives in breast cancer cells 91
The Novel Estrogen Receptor GPR30 Mediates the Proliferative Effects Induced by 17beta-Estradiol on GC-1 Mouse Spermatogonial Cell Line 91
The novel estrogen receptor, G protein-coupled receptor 30, mediates the proliferative effects induced by 17β-estradiol on mouse spermatogonial GC-1 cell line 91
Estetrol/GPER/SERPINB2 transduction signaling inhibits the motility of triple-negative breast cancer cells 90
Organo-Metallic Compounds: Novel Molecules in Cancer Therapy 88
Regulation of SLC37A1 gene expression by epidermal growth factor in breast cancer cells 88
Interaction of the Anti-Proliferative GPER Inverse Agonist ERα17p with the Breast Cancer Cell Plasma Membrane: From Biophysics to Biology 87
Recent advances on the stimulatory effects of metals in breast cancer 84
Synthesis, characterization and cytotoxic activity on breast cancer cells of new half-titanocene derivatives 83
G protein-coupled receptors: novel targets for drug discovery in cancer 82
New titanocene derivatives: synthesis and cytotoxic activity. 81
Totale 16.000
Categoria #
all - tutte 83.664
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 83.664


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021158 0 0 0 0 0 0 0 0 0 88 5 65
2021/20221.296 6 221 12 85 135 31 14 306 16 16 166 288
2022/20231.703 211 218 76 232 178 139 9 242 172 45 115 66
2023/20242.407 153 69 80 30 55 367 432 426 99 200 162 334
2024/20253.441 554 509 355 318 113 135 119 181 382 146 241 388
2025/20267.004 818 319 1.263 583 1.178 522 760 492 582 487 0 0
Totale 17.823