IRIS
SCALISE, Mariafrancesca
 Distribuzione geografica
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Continente #
NA - Nord America 3.221
AS - Asia 2.791
EU - Europa 1.848
SA - Sud America 748
AF - Africa 235
OC - Oceania 9
Continente sconosciuto - Info sul continente non disponibili 5
Totale 8.857
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Nazione #
US - Stati Uniti d'America 3.095
SG - Singapore 1.309
BR - Brasile 567
CN - Cina 554
UA - Ucraina 437
IT - Italia 418
DE - Germania 414
VN - Vietnam 356
SN - Senegal 164
HK - Hong Kong 158
FR - Francia 137
SE - Svezia 118
FI - Finlandia 89
CA - Canada 81
KR - Corea 76
AR - Argentina 73
AT - Austria 68
TR - Turchia 65
IN - India 55
BD - Bangladesh 39
ID - Indonesia 36
RU - Federazione Russa 32
GB - Regno Unito 30
EC - Ecuador 29
MX - Messico 28
IQ - Iraq 24
ZA - Sudafrica 24
JP - Giappone 23
BE - Belgio 22
PK - Pakistan 22
CO - Colombia 14
UY - Uruguay 14
CL - Cile 12
PL - Polonia 12
BO - Bolivia 11
ES - Italia 11
MA - Marocco 11
NL - Olanda 10
UZ - Uzbekistan 10
PE - Perù 9
PY - Paraguay 9
VE - Venezuela 9
AU - Australia 8
AZ - Azerbaigian 7
KZ - Kazakistan 7
SA - Arabia Saudita 7
AE - Emirati Arabi Uniti 6
EG - Egitto 6
HU - Ungheria 6
NG - Nigeria 6
RO - Romania 6
DO - Repubblica Dominicana 5
EU - Europa 5
KE - Kenya 5
LB - Libano 5
MY - Malesia 5
NP - Nepal 5
TN - Tunisia 5
CZ - Repubblica Ceca 4
OM - Oman 4
RS - Serbia 4
SK - Slovacchia (Repubblica Slovacca) 4
BY - Bielorussia 3
CI - Costa d'Avorio 3
GA - Gabon 3
IE - Irlanda 3
IR - Iran 3
JM - Giamaica 3
MD - Moldavia 3
NI - Nicaragua 3
AL - Albania 2
AM - Armenia 2
BG - Bulgaria 2
CH - Svizzera 2
CR - Costa Rica 2
HN - Honduras 2
IL - Israele 2
JO - Giordania 2
KG - Kirghizistan 2
KH - Cambogia 2
KW - Kuwait 2
LT - Lituania 2
LU - Lussemburgo 2
MT - Malta 2
BA - Bosnia-Erzegovina 1
BF - Burkina Faso 1
BH - Bahrain 1
CG - Congo 1
DK - Danimarca 1
DZ - Algeria 1
ET - Etiopia 1
GY - Guiana 1
LV - Lettonia 1
ML - Mali 1
MW - Malawi 1
NO - Norvegia 1
NR - Nauru 1
PA - Panama 1
PT - Portogallo 1
SL - Sierra Leone 1
Totale 8.853
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Città #
Singapore 520
Chandler 453
Jacksonville 249
Dallas 234
Boardman 180
Dakar 164
San Mateo 161
Hong Kong 150
Ashburn 147
Beijing 135
Ho Chi Minh City 131
Dearborn 117
Redmond 111
Munich 102
New York 99
Shanghai 78
Seoul 76
Bremen 72
Lawrence 72
Roxbury 72
Hanoi 69
Rende 68
Ann Arbor 60
Hefei 58
Cosenza 55
Helsinki 55
São Paulo 55
Vienna 51
Izmir 49
Des Moines 48
Ottawa 45
Inglewood 44
Los Angeles 44
The Dalles 44
Columbus 43
Florence 38
Brooklyn 35
Santa Clara 34
Turku 30
Ogden 29
Council Bluffs 27
Secaucus 27
Wilmington 27
Pune 24
Seattle 24
Brussels 22
Rome 22
Tokyo 22
Falkenstein 21
Haiphong 21
Guangzhou 20
Jakarta 20
Rio de Janeiro 18
Da Nang 17
Frankfurt am Main 15
San Francisco 15
Naples 14
Toronto 14
Biên Hòa 13
Guarulhos 13
Belo Horizonte 11
Curitiba 11
Redwood City 11
Baghdad 10
Buenos Aires 10
Grafing 10
Johannesburg 10
London 10
Milan 10
Montreal 10
Warsaw 10
Dhaka 9
Falls Church 9
Guayaquil 9
Montevideo 9
Nanjing 9
Salvador 9
St Petersburg 9
Boston 8
Cambridge 8
Chicago 8
Phoenix 8
Quito 8
Tashkent 8
Wuxi 8
Brasília 7
Catania 7
Recife 7
Stockholm 7
Tianjin 7
Trepuzzi 7
Wuhan 7
Atlanta 6
Baku 6
Cape Town 6
Dubai 6
La Paz 6
Lima 6
Maceió 6
Mexico City 6
Totale 5.002
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Nome #
LAT1 is the transport competent unit of the LAT1/CD98 heterodimeric amino acid transporter 263
The Human SLC1A5 (ASCT2) amino acid transporter: From function to structure and role in cell biology 161
ATP modulates SLC7A5 (LAT1) synergistically with cholesterol 159
Characterization of the CAT2 transporter from Solanum lycopersicum (Tomato). 158
Regulatory Aspects of the Vacuolar CAT2 Arginine Transporter of S. lycopersicum: Role of Osmotic Pressure and Cations 154
Insights into the transport side of the human SLC38A9 transceptor 152
Carnitine Traffic in Cells. Link With Cancer 150
Bacterial production and reconstitution in proteoliposomes of Solanum lycopersicum CAT2: a transporter of basic amino acids and organic cations 149
Exploiting Cysteine Residues of SLC Membrane Transporters as Targets for Drugs 138
Cys site-directed mutagenesis of the human SLC1A5 (ASCT2) transporter: Structure/function relationships and crucial role of Cys467 for redox sensing and glutamine transport 131
Cloning, Large Scale Over-Expression in E-coli and Purification of the Components of the Human LAT 1 (SLC7A5) Amino Acid Transporter 131
Discovery of Potent Inhibitors for the Large Neutral Amino Acid Transporter 1 (LAT1) by Structure-Based Methods 131
Cysteine is not a substrate but a specific modulator of human ASCT2 (SLC1A5) transporter. 130
Chemical Targeting of Membrane Transporters: Insights into Structure/Function Relationships 127
Glutamine transport and mitochondrial metabolism in cancer cell growth 126
Acetylcholine and acetylcarnitine transport in peritoneum: Role of the SLC22A4 (OCTN1) transporter 126
Characterization of Exosomal SLC22A5 (OCTN2) carnitine transporter 125
The human SLC7A5 (LAT1): The intriguing histidine/large neutral amino acid transporter and its relevance to human health 124
Bacterial over-expression of functionally active human CT2 (SLC22A16) carnitine transporter 123
Amino acids transport and metabolism 2.0 123
Mitochondrial Carnitine/Acylcarnitine Transporter, a Novel Target of Mercury Toxicity 120
Effect of cholesterol on the organic cation transporter OCTN1 (SLC22A4) 119
Functional and Molecular Effects of Mercury Compounds on the Human OCTN1 Cation Transporter: C50 and C136 Are the Targets for Potent Inhibition 118
Over-Expression in E. coli and Purification of the Human OCTN2 Transport Protein 115
Carnitine traffic and human fertility 114
Cysteine 467 of the ASCT2 Amino Acid Transporter Is a Molecular Determinant of the Antiport Mechanism 114
Strategies of Bacterial Over Expression of Membrane Transporters Relevant in Human Health: The Successful Case of the Three Members of OCTN Subfamily 113
Interaction of Cholesterol With the Human SLC1A5 (ASCT2): Insights Into Structure/Function Relationships 113
OCTN: A Small Transporter Subfamily with Great Relevance to Human Pathophysiology, Drug Discovery, and Diagnostics 112
Chemical approaches for studying the biology and pharmacology of membrane transporters: The histidine/large amino acid transporter slc7a5 as a benchmark 112
Exosomes in inflammation and role as biomarkers 111
A targetable antioxidant defense mechanism to EZH2 inhibitors enhances tumor cell vulnerability to ferroptosis 110
Inhibition of the carnitine acylcarnitine carrier by carbon monoxide reveals a novel mechanism of action with non-metal-containing proteins 110
OCTN Cation Transporters in Health and Disease: Role as Drug Targets and Assay Development 109
The Human SLC1A5 Neutral Amino Acid Transporter Catalyzes a pH-Dependent Glutamate/Glutamine Antiport, as Well 109
Membrane transporters for the special amino acid glutamine: structure/function relationships and relevance to human health 107
Studying interactions of drugs with cell membrane nutrient transporters: New frontiers of proteoliposome nanotechnology 107
Functional and kinetic characterization of the acetylcholine transport catalized by the recombinant human OCTN1 transporter reconstituted in liposomes. 105
Transport mechanism and regulatory properties of the human amino acid transporter ASCT2 (SLC1A5) 104
Over-expression in Escherichia coli, purification and reconstitution in liposomes of the third member of the OCTN sub-family: The mouse carnitine transporter OCTN3 103
Reconstitution in liposomes of the functionally active human OCTN1 (SLC22A4) transporter overexpressed in Escherichia coli 102
ASCT1 and ASCT2: Brother and Sister? 102
N-linked Glycosylation of human SLC1A5 (ASCT2) transporter is critical for trafficking to membrane 101
Glutamine transport. From energy supply to sensing and beyond 100
Potent inhibitors of human LAT1 (SLC7A5) transporter based on dithiazole and dithiazine compounds for development of anticancer drugs 100
Large scale production of the active human ASCT2 (SLC1A5) transporter in Pichia pastoris - functional and kinetic asymmetry revealed in proteoliposomes 99
The involvement of sodium in the function of the human amino acid transporter ASCT2 99
Human OCTN2 (SLC22A5) is down-regulated in virus- and nonvirus-mediated cancer 96
Cholesterol stimulates the cellular uptake of L-carnitine by the carnitine/organic cation transporter novel 2 (OCTN2) 94
Membrane Transporters for Amino Acids as Players of Cancer Metabolic Rewiring 92
Glutamine transporters as pharmacological targets: From function to drug design 91
Immuno-detection of OCTN1 (SLC22A4) in He La cells and characterization of transport function 90
Using liposomes to functionally characterize transport systems for glutamine and neutral amino acids 90
The human OCTN1 (SLC22A4) reconstituted in liposomes catalyzes acetylcholine transport which is defective in the mutant L503F associated to the Crohn's disease 88
OCTN1: A Widely Studied but Still Enigmatic Organic Cation Transporter Linked to Human Pathology and Drug Interactions 88
The yeast P-pastoris as a tool for large scale production of WT and mutant human amino acid transporter SLC1A5 87
Substrate-bound outward-open structure of a Na+-coupled sialic acid symporter reveals a new Na+site 86
SLC1A5 (solute carrier family 1 (neutral amino acid transporter), member 5 86
The Nutraceutical Alliin From Garlic Is a Novel Substrate of the Essential Amino Acid Transporter LAT1 (SLC7A5) 82
Over-expression and purification of the human OCTN1 and OCTN2 transporters in detergent soluble form 82
Editorial: Transport of Nutrients, Metabolites and Ions Linked to Bioenergetics: Relevance to Human Pathology 82
The Sodium Sialic acid symporter from Staphylococcus aureus has altered substrate specificity 81
Impaired Amino Acid Transport at the Blood Brain Barrier Is a Cause of Autism Spectrum Disorder 81
Regulation by physiological cations of acetylcholine transport mediated by human OCTN1 (SLC22A4). Implications in the non-neuronal cholinergic system. 80
Inactivation by omeprazole of the carnitine transporter (OCTN2) reconstituted in liposomes 80
Novel insights into the transport mechanism of the human amino acid transporter LAT1 (SLC7A5). Probing critical residues for substrate translocation 80
N-glycosylation is crucial for trafficking and stability of SLC3A2 (CD98) 79
Strategies for bacterial expression and large scale purification of human amino acid transporters. 79
OCTN1 (SLC22A4) displays two different transport pathways for organic cations or zwitterions 72
NEW INSIGHTS IN FUNCTIONAL PROPERTIES OF THE HUMAN OCTN1 TRANSPORTER: IMPLICATION IN CROHN'S DISEASE 72
Proteoliposomes as tool for assaying membrane transporter functions and interactions with xenobiotics 72
Production of recombinant human xCT (SLC7A11) and reconstitution in proteoliposomes for functional studies 71
OCTN1 (SLC22A4) as a Target of Heavy Metals: Its Possible Role in Microplastic Threats 69
Over-Production of the Human SLC7A10 in E. coli and Functional Assay in Proteoliposomes 68
IκB kinase β promotes cell survival by Antagonizing p53 functions through ΔNp73α phosphorylation and stabilization 68
Strategies for Successful Over-Expression of Human Membrane Transport Systems Using Bacterial Hosts: Future Perspectives 68
Over-expression in E. coli and reconstitution in liposomes of the OCTN3 (SLC22A21) transporter. 66
Inhibition of the Mitochondrial Carnitine/Acylcarnitine Carrier by Itaconate through Irreversible Binding to Cysteine 136: Possible Pathophysiological Implications 65
Repurposing Nimesulide, a Potent Inhibitor of the B0AT1 Subunit of the SARS-CoV-2 Receptor, as a Therapeutic Adjuvant of COVID-19 63
Nimesulide binding site in the B0AT1 (SLC6A19) amino acid transporter. Mechanism of inhibition revealed by proteoliposome transport assay and molecular modelling 62
Extracellular Vesicles and Cell Pathways Involved in Cancer Chemoresistance 61
OCTN1 mediates acetylcholine transport in the A549 lung cancer cells: possible pathophysiological implications 55
LAT1 (SLC7A5) catalyzes copper(histidinate) transport switching from antiport to uniport mechanism 55
Human papillomavirus type 38 alters wild-type p53 activity to promote cell proliferation via the downregulation of integrin alpha 1 expression 53
The Link Between the Mitochondrial Fatty Acid Oxidation Derangement and Kidney Injury 52
Lysine 204 is crucial for the antiport function of the human LAT1 transporter 50
TMBIM5 is the Ca2+ /H+ antiporter of mammalian mitochondria 48
Structure and mechanism of a tripartite ATP-independent periplasmic TRAP transporter 46
Sialic Acid Derivatives Inhibit SiaT Transporters and Delay Bacterial Growth 45
Editorial: Transport of Nutrients, Metabolites and Ions linked to Bioenergetics: Relevance to Human Pathology, Volume II 45
Production of the human carnitine transporter CT2 (SLC22A16) by bacterial expression and functional characterization in proteoliposomes 39
Structural and biophysical analysis of a Haemophilus influenzae tripartite ATP-independent periplasmic (TRAP) transporter 36
Inflammation and Organic Cation Transporters Novel (OCTNs) 31
Exploring the impact of flavin homeostasis on cancer cell metabolism 28
Totale 9.063
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Categoria #
all - tutte 55.045
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 55.045
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021447 0 0 0 0 0 82 9 93 158 62 3 40
2021/2022857 8 114 11 46 81 18 8 198 17 8 129 219
2022/20231.164 123 161 24 148 176 95 13 161 129 22 77 35
2023/2024705 59 41 47 30 57 143 33 51 53 36 38 117
2024/20251.838 78 201 54 95 146 172 131 126 190 102 204 339
2025/20263.011 617 218 490 368 987 331 0 0 0 0 0 0
Totale 9.063