GRANDE, Fedora
 Distribuzione geografica
Continente #
NA - Nord America 7.123
AS - Asia 6.095
EU - Europa 3.920
SA - Sud America 1.584
AF - Africa 420
OC - Oceania 23
Continente sconosciuto - Info sul continente non disponibili 13
AN - Antartide 1
Totale 19.179
Nazione #
US - Stati Uniti d'America 6.826
SG - Singapore 2.583
BR - Brasile 1.134
CN - Cina 1.116
UA - Ucraina 966
VN - Vietnam 961
IT - Italia 841
DE - Germania 703
AT - Austria 277
FR - Francia 269
SE - Svezia 264
IN - India 226
TR - Turchia 180
AR - Argentina 170
CA - Canada 157
KR - Corea 155
SN - Senegal 155
FI - Finlandia 142
HK - Hong Kong 141
BD - Bangladesh 114
IQ - Iraq 113
GB - Regno Unito 111
ID - Indonesia 89
ZA - Sudafrica 86
MX - Messico 78
EC - Ecuador 69
RU - Federazione Russa 62
PK - Pakistan 61
CO - Colombia 57
JP - Giappone 46
NL - Olanda 41
BE - Belgio 40
PL - Polonia 40
EG - Egitto 39
VE - Venezuela 39
ES - Italia 38
SA - Arabia Saudita 37
UZ - Uzbekistan 35
MA - Marocco 33
PY - Paraguay 33
CL - Cile 32
PH - Filippine 30
TN - Tunisia 22
IE - Irlanda 21
AE - Emirati Arabi Uniti 20
AU - Australia 20
DO - Repubblica Dominicana 18
DZ - Algeria 18
KE - Kenya 18
PE - Perù 18
AZ - Azerbaigian 17
NP - Nepal 17
UY - Uruguay 16
JO - Giordania 15
MY - Malesia 14
AL - Albania 12
EU - Europa 12
PS - Palestinian Territory 12
BO - Bolivia 11
CZ - Repubblica Ceca 11
OM - Oman 11
LT - Lituania 10
CR - Costa Rica 9
TW - Taiwan 9
ET - Etiopia 8
GR - Grecia 8
JM - Giamaica 8
KZ - Kazakistan 8
SY - Repubblica araba siriana 8
BY - Bielorussia 7
CI - Costa d'Avorio 7
GE - Georgia 7
LB - Libano 7
LK - Sri Lanka 7
TH - Thailandia 7
AM - Armenia 6
BG - Bulgaria 6
IR - Iran 6
KG - Kirghizistan 6
RO - Romania 6
BA - Bosnia-Erzegovina 5
IL - Israele 5
KW - Kuwait 5
LV - Lettonia 5
NG - Nigeria 5
NI - Nicaragua 5
PA - Panama 5
BN - Brunei Darussalam 4
EE - Estonia 4
GA - Gabon 4
GH - Ghana 4
HR - Croazia 4
KH - Cambogia 4
LY - Libia 4
MD - Moldavia 4
PT - Portogallo 4
QA - Qatar 4
RS - Serbia 4
SV - El Salvador 4
TG - Togo 4
Totale 19.119
Città #
Singapore 1.032
Chandler 757
Dallas 726
San Jose 668
Jacksonville 550
Ashburn 502
Boardman 393
Ho Chi Minh City 357
Beijing 314
Dearborn 313
San Mateo 303
Hanoi 238
New York 226
Vienna 201
Rende 167
Lauterbourg 158
Dakar 155
Lawrence 140
Roxbury 139
Seoul 135
Hong Kong 132
Shanghai 128
Hefei 112
Helsinki 102
Izmir 97
Brooklyn 95
Munich 95
Los Angeles 94
Des Moines 92
Ann Arbor 90
Ottawa 84
São Paulo 84
Florence 67
Cambridge 66
Baghdad 52
Haiphong 51
Ogden 49
Wilmington 47
Bremen 45
Council Bluffs 45
Da Nang 45
Grafing 45
Toronto 45
Pune 41
The Dalles 41
Guangzhou 39
Brussels 38
Rio de Janeiro 37
Cosenza 35
Tokyo 35
Turku 35
Inglewood 34
Milan 34
Columbus 33
Rome 33
Tashkent 33
Johannesburg 32
Santa Clara 32
San Francisco 29
Warsaw 29
Chennai 27
Quito 27
Redwood City 23
Jakarta 22
Frankfurt am Main 21
Tianjin 21
Cairo 20
Chicago 20
Belo Horizonte 19
Buenos Aires 19
Dhaka 19
Mexico City 19
Seattle 19
Catanzaro 18
Dublin 18
Faisalabad 18
Istanbul 17
Orem 17
Amsterdam 16
Ankara 16
Asunción 16
London 16
Manchester 16
Amman 15
Basingstoke 15
Bogotá 15
Cape Town 15
Norwalk 15
Santiago 15
Baku 14
Brasília 14
Curitiba 14
Mumbai 14
Nairobi 14
Naples 14
Ninh Bình 14
Riyadh 14
Bari 13
Boston 13
Catania 13
Totale 10.511
Nome #
Exploring by-products as sources of bioactive compounds: LC-ESI-QTOF-MS profiling and bioactivity assessment of blood twig dogwood and cornelian cherry leaf extracts and fractions 271
A pilot study on the nutraceutical properties of the Citrus hybrid Tacle® as a dietary source of polyphenols for supplementation in metabolic disorders 223
AHR and GPER mediate the stimulatory effects induced by 3-methylcholanthrene in breast cancer cells and cancer-associated fibroblasts (CAFs) 216
Computational Approaches for the Discovery of GPER Targeting Compounds 212
A critical study on the zero-crossing method in derivative spectrophotometry 204
Benzothienoquinazolinones as new multi-target scaffolds: Dual inhibition of human Topoisomerase I and tubulin polymerization 194
Acute and synergistic toxicity of drugs in water by luminescent bacteria assay 193
An approach to the stereo-controlled synthesis of polycyclic derivatives of L-4-thiazolidinecarboxylic acid active against HIV-1 integrase 192
Antihypertensive effects of novel Quercetin derivatives 190
Antihypertensive effects of novel Quercetin derivatives 189
Lipid lowering and antiglycaemic properties of Tacle® by in vitro and in vivo investigation 189
Assessment of surface water quality using multivariate analysis: Case study of the crati River, Italy 189
CCR5/CXCR4 dual antagonism for the improvement of HIV infection therapy 182
Benzothienoquinazolinones as new inhibitor of Topoisomerases and Tubulin 175
Active manganese dioxide promoted cyclization of ortho-(1H-pyrrol- 1-yl)aryl and heteroaryl carboxylic acids to 5H-pyrrolo[1,2-a][3,1] benzoxazin-5-one derivatives 173
"Gel formulation of Nabumetone and a newly synthesized analog: Microemulsion as a photoprotective topical delivery system" in PHARMACEUTICS AND ADVANCED DRUG DELIVERY SYSTEMS 172
STUDI ACCELERATI DI FOTOSTABILITÀ DEI FARMACI. 171
Synthesis and biological evaluation of 1,3-Indandione derivatives as acetylcholinesterase inhibitors 170
Discovery of potential pancreatic lipase inhibitors from Salvia miltiorrhiza Bunge 170
Photo and thermal stress of linseed oil and stabilization strategies 170
A challenge in the treatment of neuropathic pain: synthesis of new photostable dihydropyridines 169
Cateslytin abrogates lipopolysaccharide-induced cardiomyocyte injury by reducing inflammation and oxidative stress through toll like receptor 4 interaction 168
A new generation of dihydropyridine calcium channel blockers: Photostabilization of liquid formulations using nonionic surfactants 167
Quercetin and its derivative Q2 modulate chromatin dynamics in adipogenesis and Q2 prevents obesity and metabolic disorders in rats 167
Quercetin derivatives as novel antihypertensive agents: Synthesis and physiological characterization 166
Cryptotanshinone and tanshinone IIA from Salvia milthorrhiza Bunge (Danshen) as a new class of potential pancreatic lipase inhibitors 166
An update on small molecules targeting CXCR4 as starting points for the development of anti-cancer therapeutics. 165
Molecular docking studies towards exploring potential anti-estrogen activity of two natural homoisoflavones P117 164
Antihypertensive effects of novel quercetin derivatives. 163
Cyclodextrin matrices as photoprotective systems of anti-inflammatory agents for topical use 163
Stability indicating method of Nabmetone and congeners in microemulsion by MCR analysis. 163
Identification by molecular docking of homoisoflavones from leopoldia comosa as ligands of estrogen receptors 162
A critical study on the application of the zero-crossing derivative spectrophotometry to the photodegradation monitoring of lacidipine 162
Identification of chlorocarbazole derivatives as potential antiviral agents. 159
New insights for the use of quercetin analogs in cancer treatment 158
Combination effects of SC144 and cytotoxic anticancer agents 156
Benzopyrroloxazines containing a bridgehead nitrogen atom as promising scaffolds for the achievement of biologically active agents 155
Identification of two benzopyrroloxazines acting as selective GPER antagonists in breast cancer cells and cancer-associated fibroblasts 153
Carbazole derivatives as kinase-targeting inhibitors for cancer treatment 153
Homoisoflavones as ligands of estrogen receptors: novel tools for hormone sensitive cancer treatment 147
Molecular docking of two homoisoflavones as ligand of estrogen receptors 147
Synthesis and anti-tumor activities of a series of novel quinoxalinhydrazides 146
Anticancer Drugs: Recent Strategies to Improve Stability Profile, Pharmacokinetic and Pharmacodynamic Properties 144
Combination of hormones and nutrients for the development of hybrid nutraceuticals. 142
Effects of nonionic surfactants on water solubilization and photoprotection of new 1,4-dhydropyridine drugs. 142
Antiproliferative effects of new N-alkylamino carbazole derivatives on breast cancer cell lines. 142
Cyclodextrins in topical gel formulation as photoprotective system for Nabumetone 142
Chloro-1,4-dimethyl-9H-carbazole Derivatives Displaying Anti-HIV Activity 141
Benzodiazepines and Related Substances: Chemistry 140
Carbazole and simplified derivatives: Novel tools toward β-adrenergic receptors targeting 137
QUERCETIN DERIVATIVES AS NOVEL ANTICANCER AGENTS 136
Gel formulation of nabumetone and a newly synthesized analog: Microemulsion as a photoprotective topical delivery system 136
Identification of novel 2-(1 H-indol-1-yl)-benzohydrazides CXCR4 ligands impairing breast cancer growth & motility 135
Naturally occurring homoisoflavonoids as novel tools against breast cancer 135
Ligand-activated PPARγ downregulates CXCR4 gene expression through a novel identified PPAR response element and inhibits breast cancer progression 133
Liquid crystalline microspheres for 5-fluorouracil specific release 133
Titanium Dioxide Nanoparticles: A Risk for Human Health? 131
DESIGN OF LIGHT-STABLE FORMULATIONS OF NABUMETONE FOR TOPICAL USE: PHOTODEGRADATION STUDIES AND EX VIVO PERMEATION TESTS 130
The Peptide ERα17p Is a GPER Inverse Agonist that Exerts Antiproliferative Effects in Breast Cancer Cells 130
Reverse transcriptase inhibitors nanosystems designed for drug stability and controlled delivery 130
The chromogranin A1-373 fragment reveals how a single change in the protein sequence exerts strong cardioregulatory effects by engaging neuropilin-1 129
The G Protein Estrogen Receptor (GPER) is involved in the resistance to the CDK4/6 inhibitor palbociclib in breast cancer 128
Identification of two novel benzo[b]pyrrolo[1,2-d][1,4]oxazin-4-one derivatives acting as GPER antagonists 127
Polyphenols from citrus tacle® extract endowed with hmgcr inhibitory activity: An antihypercholesterolemia natural remedy 126
Antiproliferative effects of new carbazole derivative on breast cancer cell lines. 125
p53: una questione di vita o di morte. Una proteina chiave in oncologia 125
Chapter 15 Outdoor Air Pollutants 123
Photostability of newly synthesized 1,4 dihydropyridines: MCR modelling and HPLC analysis 122
Titanium dioxide nanoparticles: metabolic profiling on human keratinocytes 120
Leptin Signaling Contributes to Aromatase Inhibitor Resistant Breast Cancer Cell Growth and Activation of Macrophages 118
Small molecule inhibitors of CXCR4 116
Small molecule inhibitors of Stat3 signaling pathway 115
Convenient synthesis of fluorazone derivatives by one-pot pyrrolation/cyclization of anthranilic acids 113
Design, synthesis and biological evaluation of 7-substituted 4-phenyl-6H-imidazo[1,5-a]thieno[3,2-f] [1,4]diazepines as safe anxiolytic agents 112
Use of Pluronic Surfactants in Gel Formulations of Photosensitive 1,4-Dihydropyridine Derivatives: A Potential Approach in the Treatment of Neuropathic Pain 112
Cytotoxic potential of novel 6,7-dimethoxyquinazolines 111
Small-Molecule Inhibitors of p53-MDM2 Interaction: the 2006-2010 Update 110
Quercetin Derivatives: evaluation of anti-proliferative activity and inhibition of human Topoisomerases I and II 108
Design and Synthesis of 3-Carbamoylbenzoic Derivatives as Inhibitors of Human Apurinic/Apyrimidinic Endonuclease 1 (APE1) 108
TiO2-NPs Toxicity and Safety: An Update of the Findings Published over the Last Six Years 107
DERIVATI DELLA QUERCETINA AD ELEVATA STABILITÀ NELLA PREVENZIONE DELLO STRESS OSSIDATIVO 107
Design, Synthesis and Biological Evaluation of Naphthoxazepine Inhibitors of HIV-1-Integrase 106
Multivariate curve resolution for the simultaneous kinetic analysis of multicomponent photolabile drug formulations 106
Synthesis and photodegradation studies of analogues of muscle relaxant 1,4-dihydropyridine compounds 105
Development of PARP-1 inhibitors as novel anticancer drugs 105
Study of the Photodegradation Kinetics of Multicomponent Drug Formulations via MCR-ALS: The Case of the Amiloride-hydrochlorothiazide Mixture 105
SINTESI DI ANALOGHI STRUTTURALI DEL NABUMETONE PER USO TOPICO: STUDI DI FOTODEGRADAZIONE E DESIGN DI FORMULAZIONI FOTOSTABILI 103
Small molecules anti-HIV therapeutics targeting CXCR4 101
Composition and Methods For Treating Colon and Ovarian Cancer. 101
Synthesis and biological evaluation of novel hydrazide based cytotoxic agents 100
Photostability study of multicomponent drug formulations via MCR-ALS: The case of the hydrochlorothiazide-amiloride mixture 100
Direct cyclization of ortho-(1H-pyrrol-1-yl)aryl and heteroaryl carboxylic acids into fused pyrrolizinones 99
Discovery of Novel Anticancer Compounds Based on Quinoxalinhydrazide Pharmacophore 98
Quinoxalinhydrazide Pharmacophore Based identification of Novel Anticancer Compounds 97
Stabilization of MDA-7/IL-24 for colon cancer therapy 97
Valutazione della tossicità acuta di piante medicinali mediante microtox test. 96
Synthesis of nabumetone analogues for topical use: photodegradation studies and design of light-stable formulations 96
Dissecting CYP1A2 Activation by Arylalkanoic Acid Prodrugs toward the Development of Anti-Inflammatory Agents 95
Multivariate Curve Resolution Methodology Applied to the ATR-FTIR Data for Adulteration Assessment of Virgin Coconut Oil 95
Hydrazide-based inhibitors of HDAC enzymes as novel anticancer drugs 95
Totale 14.185
Categoria #
all - tutte 101.627
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 101.627


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021261 0 0 0 0 0 0 0 0 0 150 18 93
2021/20221.706 28 248 34 95 195 61 28 343 23 9 221 421
2022/20231.989 283 242 93 237 216 165 10 223 208 54 146 112
2023/20241.495 150 56 97 83 99 366 68 66 111 63 76 260
2024/20253.021 197 393 113 176 232 159 120 170 511 222 296 432
2025/20268.452 1.044 397 1.117 668 1.601 759 1.074 517 651 624 0 0
Totale 19.535