GRANDE, Fedora
 Distribuzione geografica
Continente #
NA - Nord America 7.724
AS - Asia 6.341
EU - Europa 4.085
SA - Sud America 1.584
AF - Africa 420
OC - Oceania 24
Continente sconosciuto - Info sul continente non disponibili 13
AN - Antartide 1
Totale 20.192
Nazione #
US - Stati Uniti d'America 7.398
SG - Singapore 2.607
CN - Cina 1.188
BR - Brasile 1.134
IT - Italia 997
UA - Ucraina 966
VN - Vietnam 965
DE - Germania 708
AT - Austria 277
FR - Francia 268
SE - Svezia 264
BD - Bangladesh 240
IN - India 227
TR - Turchia 180
AR - Argentina 170
CA - Canada 170
KR - Corea 156
SN - Senegal 155
HK - Hong Kong 146
FI - Finlandia 142
IQ - Iraq 113
GB - Regno Unito 112
ID - Indonesia 91
ZA - Sudafrica 86
MX - Messico 83
EC - Ecuador 69
PK - Pakistan 62
RU - Federazione Russa 61
CO - Colombia 57
JP - Giappone 47
BE - Belgio 42
NL - Olanda 42
PL - Polonia 40
EG - Egitto 39
VE - Venezuela 39
ES - Italia 38
SA - Arabia Saudita 37
UZ - Uzbekistan 35
MA - Marocco 33
PY - Paraguay 33
CL - Cile 32
PH - Filippine 31
TN - Tunisia 22
AE - Emirati Arabi Uniti 21
AU - Australia 21
IE - Irlanda 21
MY - Malesia 19
NP - Nepal 19
DO - Repubblica Dominicana 18
DZ - Algeria 18
KE - Kenya 18
PE - Perù 18
AZ - Azerbaigian 17
UY - Uruguay 16
JO - Giordania 15
JM - Giamaica 13
AL - Albania 12
EU - Europa 12
PS - Palestinian Territory 12
BO - Bolivia 11
CZ - Repubblica Ceca 11
OM - Oman 11
CR - Costa Rica 10
LT - Lituania 10
TW - Taiwan 9
ET - Etiopia 8
GR - Grecia 8
KZ - Kazakistan 8
NI - Nicaragua 8
SY - Repubblica araba siriana 8
BY - Bielorussia 7
CI - Costa d'Avorio 7
GE - Georgia 7
LB - Libano 7
LK - Sri Lanka 7
TH - Thailandia 7
AM - Armenia 6
BG - Bulgaria 6
IR - Iran 6
KG - Kirghizistan 6
RO - Romania 6
BA - Bosnia-Erzegovina 5
CH - Svizzera 5
IL - Israele 5
KW - Kuwait 5
LV - Lettonia 5
NG - Nigeria 5
SV - El Salvador 5
BN - Brunei Darussalam 4
EE - Estonia 4
GA - Gabon 4
GH - Ghana 4
HN - Honduras 4
HR - Croazia 4
KH - Cambogia 4
LY - Libia 4
MD - Moldavia 4
PA - Panama 4
PT - Portogallo 4
QA - Qatar 4
Totale 20.129
Città #
Singapore 1.035
Chandler 757
Dallas 735
San Jose 722
Jacksonville 551
Ashburn 534
Boardman 393
Ho Chi Minh City 360
Beijing 327
Dearborn 313
San Mateo 303
Council Bluffs 267
New York 262
Hanoi 238
Vienna 201
Rende 167
Lauterbourg 158
Dakar 155
Lawrence 140
Roxbury 139
Hong Kong 136
Seoul 135
Shanghai 129
Hefei 113
Los Angeles 103
Helsinki 102
Brooklyn 98
Izmir 97
Munich 95
Des Moines 93
Ann Arbor 90
Ottawa 85
São Paulo 84
Florence 70
Cambridge 66
Columbus 61
Rome 54
Baghdad 52
Haiphong 51
Ogden 50
Santa Clara 49
Toronto 47
Wilmington 47
Bremen 45
Da Nang 45
Grafing 45
Milan 43
Pune 41
The Dalles 41
Guangzhou 39
Brussels 38
Rio de Janeiro 37
Cosenza 35
Tokyo 35
Turku 35
Inglewood 34
Tashkent 33
Johannesburg 32
San Francisco 29
Warsaw 29
Chennai 27
Chicago 27
Quito 27
Naples 26
Mexico City 23
Redwood City 23
Jakarta 22
Bari 21
Frankfurt am Main 21
Tianjin 21
Cairo 20
Catanzaro 20
Omaha 20
Belo Horizonte 19
Buenos Aires 19
Dhaka 19
Seattle 19
Buffalo 18
Dublin 18
Faisalabad 18
Istanbul 17
Orem 17
Amsterdam 16
Ankara 16
Asunción 16
London 16
Manchester 16
Amman 15
Basingstoke 15
Bogotá 15
Cape Town 15
Catania 15
Norwalk 15
Santiago 15
Baku 14
Boston 14
Brasília 14
Curitiba 14
Düsseldorf 14
Mumbai 14
Totale 11.031
Nome #
Exploring by-products as sources of bioactive compounds: LC-ESI-QTOF-MS profiling and bioactivity assessment of blood twig dogwood and cornelian cherry leaf extracts and fractions 292
A pilot study on the nutraceutical properties of the Citrus hybrid Tacle® as a dietary source of polyphenols for supplementation in metabolic disorders 240
AHR and GPER mediate the stimulatory effects induced by 3-methylcholanthrene in breast cancer cells and cancer-associated fibroblasts (CAFs) 229
Computational Approaches for the Discovery of GPER Targeting Compounds 221
A critical study on the zero-crossing method in derivative spectrophotometry 207
Antihypertensive effects of novel Quercetin derivatives 197
Benzothienoquinazolinones as new multi-target scaffolds: Dual inhibition of human Topoisomerase I and tubulin polymerization 197
Acute and synergistic toxicity of drugs in water by luminescent bacteria assay 196
An approach to the stereo-controlled synthesis of polycyclic derivatives of L-4-thiazolidinecarboxylic acid active against HIV-1 integrase 195
Antihypertensive effects of novel Quercetin derivatives 192
Assessment of surface water quality using multivariate analysis: Case study of the crati River, Italy 191
Lipid lowering and antiglycaemic properties of Tacle® by in vitro and in vivo investigation 189
Anticancer Drugs: Recent Strategies to Improve Stability Profile, Pharmacokinetic and Pharmacodynamic Properties 187
Quercetin derivatives as novel antihypertensive agents: Synthesis and physiological characterization 186
CCR5/CXCR4 dual antagonism for the improvement of HIV infection therapy 183
Homoisoflavones as ligands of estrogen receptors: novel tools for hormone sensitive cancer treatment 182
STUDI ACCELERATI DI FOTOSTABILITÀ DEI FARMACI. 178
A new generation of dihydropyridine calcium channel blockers: Photostabilization of liquid formulations using nonionic surfactants 178
Active manganese dioxide promoted cyclization of ortho-(1H-pyrrol- 1-yl)aryl and heteroaryl carboxylic acids to 5H-pyrrolo[1,2-a][3,1] benzoxazin-5-one derivatives 177
Synthesis and biological evaluation of 1,3-Indandione derivatives as acetylcholinesterase inhibitors 176
Discovery of potential pancreatic lipase inhibitors from Salvia miltiorrhiza Bunge 176
Benzothienoquinazolinones as new inhibitor of Topoisomerases and Tubulin 176
Photo and thermal stress of linseed oil and stabilization strategies 175
"Gel formulation of Nabumetone and a newly synthesized analog: Microemulsion as a photoprotective topical delivery system" in PHARMACEUTICS AND ADVANCED DRUG DELIVERY SYSTEMS 174
Quercetin and its derivative Q2 modulate chromatin dynamics in adipogenesis and Q2 prevents obesity and metabolic disorders in rats 172
A challenge in the treatment of neuropathic pain: synthesis of new photostable dihydropyridines 170
Cateslytin abrogates lipopolysaccharide-induced cardiomyocyte injury by reducing inflammation and oxidative stress through toll like receptor 4 interaction 169
Chloro-1,4-dimethyl-9H-carbazole Derivatives Displaying Anti-HIV Activity 167
Cryptotanshinone and tanshinone IIA from Salvia milthorrhiza Bunge (Danshen) as a new class of potential pancreatic lipase inhibitors 167
Identification of chlorocarbazole derivatives as potential antiviral agents. 166
Identification by molecular docking of homoisoflavones from leopoldia comosa as ligands of estrogen receptors 166
An update on small molecules targeting CXCR4 as starting points for the development of anti-cancer therapeutics. 166
Antihypertensive effects of novel quercetin derivatives. 165
Benzopyrroloxazines containing a bridgehead nitrogen atom as promising scaffolds for the achievement of biologically active agents 165
A critical study on the application of the zero-crossing derivative spectrophotometry to the photodegradation monitoring of lacidipine 165
Cyclodextrin matrices as photoprotective systems of anti-inflammatory agents for topical use 165
Molecular docking studies towards exploring potential anti-estrogen activity of two natural homoisoflavones P117 164
Stability indicating method of Nabmetone and congeners in microemulsion by MCR analysis. 163
Identification of two benzopyrroloxazines acting as selective GPER antagonists in breast cancer cells and cancer-associated fibroblasts 162
New insights for the use of quercetin analogs in cancer treatment 159
Combination effects of SC144 and cytotoxic anticancer agents 159
Carbazole derivatives as kinase-targeting inhibitors for cancer treatment 158
Molecular docking of two homoisoflavones as ligand of estrogen receptors 153
Ligand-activated PPARγ downregulates CXCR4 gene expression through a novel identified PPAR response element and inhibits breast cancer progression 151
Synthesis and anti-tumor activities of a series of novel quinoxalinhydrazides 148
Liquid crystalline microspheres for 5-fluorouracil specific release 146
Cyclodextrins in topical gel formulation as photoprotective system for Nabumetone 146
Effects of nonionic surfactants on water solubilization and photoprotection of new 1,4-dhydropyridine drugs. 144
Antiproliferative effects of new N-alkylamino carbazole derivatives on breast cancer cell lines. 144
Benzodiazepines and Related Substances: Chemistry 144
Combination of hormones and nutrients for the development of hybrid nutraceuticals. 143
Carbazole and simplified derivatives: Novel tools toward β-adrenergic receptors targeting 142
Antiproliferative effects of new carbazole derivative on breast cancer cell lines. 140
QUERCETIN DERIVATIVES AS NOVEL ANTICANCER AGENTS 140
Identification of novel 2-(1 H-indol-1-yl)-benzohydrazides CXCR4 ligands impairing breast cancer growth & motility 139
Gel formulation of nabumetone and a newly synthesized analog: Microemulsion as a photoprotective topical delivery system 137
The G Protein Estrogen Receptor (GPER) is involved in the resistance to the CDK4/6 inhibitor palbociclib in breast cancer 136
Naturally occurring homoisoflavonoids as novel tools against breast cancer 136
Titanium Dioxide Nanoparticles: A Risk for Human Health? 135
The chromogranin A1-373 fragment reveals how a single change in the protein sequence exerts strong cardioregulatory effects by engaging neuropilin-1 134
Identification of two novel benzo[b]pyrrolo[1,2-d][1,4]oxazin-4-one derivatives acting as GPER antagonists 133
The Peptide ERα17p Is a GPER Inverse Agonist that Exerts Antiproliferative Effects in Breast Cancer Cells 132
Reverse transcriptase inhibitors nanosystems designed for drug stability and controlled delivery 132
Polyphenols from citrus tacle® extract endowed with hmgcr inhibitory activity: An antihypercholesterolemia natural remedy 131
DESIGN OF LIGHT-STABLE FORMULATIONS OF NABUMETONE FOR TOPICAL USE: PHOTODEGRADATION STUDIES AND EX VIVO PERMEATION TESTS 130
p53: una questione di vita o di morte. Una proteina chiave in oncologia 128
Photostability of newly synthesized 1,4 dihydropyridines: MCR modelling and HPLC analysis 126
Small molecule inhibitors of CXCR4 126
Titanium dioxide nanoparticles: metabolic profiling on human keratinocytes 125
Chapter 15 Outdoor Air Pollutants 124
TiO2-NPs Toxicity and Safety: An Update of the Findings Published over the Last Six Years 120
Leptin Signaling Contributes to Aromatase Inhibitor Resistant Breast Cancer Cell Growth and Activation of Macrophages 120
Discovery of Novel Anticancer Compounds Based on Quinoxalinhydrazide Pharmacophore 119
Small molecule inhibitors of Stat3 signaling pathway 118
Cytotoxic potential of novel 6,7-dimethoxyquinazolines 117
Stabilization of MDA-7/IL-24 for colon cancer therapy 117
Convenient synthesis of fluorazone derivatives by one-pot pyrrolation/cyclization of anthranilic acids 116
Quercetin Derivatives: evaluation of anti-proliferative activity and inhibition of human Topoisomerases I and II 115
Design and Synthesis of 3-Carbamoylbenzoic Derivatives as Inhibitors of Human Apurinic/Apyrimidinic Endonuclease 1 (APE1) 115
Use of Pluronic Surfactants in Gel Formulations of Photosensitive 1,4-Dihydropyridine Derivatives: A Potential Approach in the Treatment of Neuropathic Pain 115
Design, synthesis and biological evaluation of 7-substituted 4-phenyl-6H-imidazo[1,5-a]thieno[3,2-f] [1,4]diazepines as safe anxiolytic agents 114
Stabilization strategies for photosensitive drugs 112
Valutazione della tossicità acuta di piante medicinali mediante microtox test. 111
Hydrazide-based inhibitors of HDAC enzymes as novel anticancer drugs 111
Small-Molecule Inhibitors of p53-MDM2 Interaction: the 2006-2010 Update 110
Design, Synthesis and Biological Evaluation of Naphthoxazepine Inhibitors of HIV-1-Integrase 110
Estetrol/GPER/SERPINB2 transduction signaling inhibits the motility of triple-negative breast cancer cells 109
Development of PARP-1 inhibitors as novel anticancer drugs 109
SINTESI DI ANALOGHI STRUTTURALI DEL NABUMETONE PER USO TOPICO: STUDI DI FOTODEGRADAZIONE E DESIGN DI FORMULAZIONI FOTOSTABILI 109
DERIVATI DELLA QUERCETINA AD ELEVATA STABILITÀ NELLA PREVENZIONE DELLO STRESS OSSIDATIVO 109
Synthesis and photodegradation studies of analogues of muscle relaxant 1,4-dihydropyridine compounds 108
Study of the Photodegradation Kinetics of Multicomponent Drug Formulations via MCR-ALS: The Case of the Amiloride-hydrochlorothiazide Mixture 107
Multivariate curve resolution for the simultaneous kinetic analysis of multicomponent photolabile drug formulations 107
Dissecting CYP1A2 Activation by Arylalkanoic Acid Prodrugs toward the Development of Anti-Inflammatory Agents 106
Composition and Methods For Treating Colon and Ovarian Cancer. 105
Direct cyclization of ortho-(1H-pyrrol-1-yl)aryl and heteroaryl carboxylic acids into fused pyrrolizinones 105
Interaction of letrozole and its degradation products with aromatase: chemometric assessment of kinetics and structure-based binding validation 104
Quinoxalinhydrazide Pharmacophore Based identification of Novel Anticancer Compounds 104
Synthesis and biological evaluation of novel hydrazide based cytotoxic agents 103
Small molecules anti-HIV therapeutics targeting CXCR4 102
Totale 14.834
Categoria #
all - tutte 106.681
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 106.681


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202193 0 0 0 0 0 0 0 0 0 0 0 93
2021/20221.706 28 248 34 95 195 61 28 343 23 9 221 421
2022/20231.989 283 242 93 237 216 165 10 223 208 54 146 112
2023/20241.495 150 56 97 83 99 366 68 66 111 63 76 260
2024/20253.021 197 393 113 176 232 159 120 170 511 222 296 432
2025/20269.467 1.044 397 1.117 668 1.601 747 1.070 513 649 679 504 478
Totale 20.550