IRIS
GRANDE, Fedora
 Distribuzione geografica
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Continente #
NA - Nord America 8.353
AS - Asia 6.494
EU - Europa 4.225
SA - Sud America 1.618
AF - Africa 420
Continente sconosciuto - Info sul continente non disponibili 371
OC - Oceania 24
AN - Antartide 1
Totale 21.506
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Nazione #
US - Stati Uniti d'America 7.990
SG - Singapore 2.613
CN - Cina 1.240
BR - Brasile 1.154
IT - Italia 1.122
VN - Vietnam 975
UA - Ucraina 967
DE - Germania 710
BD - Bangladesh 288
AT - Austria 277
FR - Francia 270
SE - Svezia 264
IN - India 239
CA - Canada 187
TR - Turchia 180
AR - Argentina 174
KR - Corea 156
SN - Senegal 155
HK - Hong Kong 147
FI - Finlandia 142
GB - Regno Unito 119
IQ - Iraq 113
ID - Indonesia 95
ZA - Sudafrica 86
MX - Messico 83
EC - Ecuador 70
CO - Colombia 62
PK - Pakistan 62
RU - Federazione Russa 61
JP - Giappone 48
BE - Belgio 42
NL - Olanda 42
VE - Venezuela 41
PL - Polonia 40
EG - Egitto 39
ES - Italia 38
SA - Arabia Saudita 38
PH - Filippine 35
UZ - Uzbekistan 35
CL - Cile 34
MA - Marocco 33
PY - Paraguay 33
MY - Malesia 24
AE - Emirati Arabi Uniti 22
IE - Irlanda 22
TN - Tunisia 22
AU - Australia 21
NP - Nepal 20
DO - Repubblica Dominicana 18
DZ - Algeria 18
KE - Kenya 18
PE - Perù 18
AZ - Azerbaigian 17
JM - Giamaica 17
UY - Uruguay 16
CR - Costa Rica 15
JO - Giordania 15
AL - Albania 12
EU - Europa 12
PS - Palestinian Territory 12
TH - Thailandia 12
BO - Bolivia 11
CZ - Repubblica Ceca 11
OM - Oman 11
LT - Lituania 10
GR - Grecia 9
NI - Nicaragua 9
TW - Taiwan 9
AM - Armenia 8
ET - Etiopia 8
KZ - Kazakistan 8
SY - Repubblica araba siriana 8
BY - Bielorussia 7
CI - Costa d'Avorio 7
GE - Georgia 7
HN - Honduras 7
LB - Libano 7
LK - Sri Lanka 7
BG - Bulgaria 6
IR - Iran 6
KG - Kirghizistan 6
RO - Romania 6
TT - Trinidad e Tobago 6
BA - Bosnia-Erzegovina 5
CH - Svizzera 5
IL - Israele 5
KW - Kuwait 5
LV - Lettonia 5
NG - Nigeria 5
SV - El Salvador 5
BN - Brunei Darussalam 4
EE - Estonia 4
GA - Gabon 4
GH - Ghana 4
HR - Croazia 4
KH - Cambogia 4
LY - Libia 4
MD - Moldavia 4
PA - Panama 4
PT - Portogallo 4
Totale 21.079
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Città #
Singapore 1.039
Chandler 757
Dallas 745
San Jose 723
Ashburn 578
Jacksonville 553
Council Bluffs 501
Boardman 393
Ho Chi Minh City 365
Beijing 335
Dearborn 314
San Mateo 303
New York 285
Hanoi 239
Vienna 201
Rende 167
Lauterbourg 158
Dakar 155
Lawrence 140
Roxbury 139
Hong Kong 137
Seoul 135
Shanghai 129
Hefei 113
Los Angeles 113
Santa Clara 107
Helsinki 102
Brooklyn 99
Izmir 97
Milan 96
Munich 95
Des Moines 94
São Paulo 92
Ann Arbor 90
Ottawa 85
Rome 75
Florence 70
Cambridge 66
Columbus 61
Baghdad 52
Haiphong 52
Toronto 51
Ogden 50
Wilmington 48
Da Nang 46
Bremen 45
Grafing 45
Pune 41
The Dalles 41
Guangzhou 39
Brussels 38
Rio de Janeiro 38
Cosenza 35
Tokyo 35
Turku 35
Inglewood 34
Omaha 34
San Francisco 33
Tashkent 33
Johannesburg 32
Chicago 31
Warsaw 29
Chennai 27
Quito 27
Naples 26
Buffalo 24
Mumbai 24
Frankfurt am Main 23
Jakarta 23
Mexico City 23
Redwood City 23
Bari 22
London 22
Tianjin 22
Cairo 20
Catanzaro 20
Dhaka 20
Belo Horizonte 19
Buenos Aires 19
Phoenix 19
Seattle 19
Dublin 18
Faisalabad 18
Bogotá 17
Istanbul 17
Orem 17
Amsterdam 16
Ankara 16
Asunción 16
Boston 16
Manchester 16
Amman 15
Basingstoke 15
Brasília 15
Cape Town 15
Catania 15
Norwalk 15
Santiago 15
Turin 15
Baku 14
Totale 11.586
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Nome #
Exploring by-products as sources of bioactive compounds: LC-ESI-QTOF-MS profiling and bioactivity assessment of blood twig dogwood and cornelian cherry leaf extracts and fractions 297
Computational Approaches for the Discovery of GPER Targeting Compounds 275
A pilot study on the nutraceutical properties of the Citrus hybrid Tacle® as a dietary source of polyphenols for supplementation in metabolic disorders 249
AHR and GPER mediate the stimulatory effects induced by 3-methylcholanthrene in breast cancer cells and cancer-associated fibroblasts (CAFs) 239
A critical study on the zero-crossing method in derivative spectrophotometry 208
Active manganese dioxide promoted cyclization of ortho-(1H-pyrrol- 1-yl)aryl and heteroaryl carboxylic acids to 5H-pyrrolo[1,2-a][3,1] benzoxazin-5-one derivatives 207
An approach to the stereo-controlled synthesis of polycyclic derivatives of L-4-thiazolidinecarboxylic acid active against HIV-1 integrase 202
Acute and synergistic toxicity of drugs in water by luminescent bacteria assay 202
Antihypertensive effects of novel Quercetin derivatives 200
Benzothienoquinazolinones as new multi-target scaffolds: Dual inhibition of human Topoisomerase I and tubulin polymerization 200
Anticancer Drugs: Recent Strategies to Improve Stability Profile, Pharmacokinetic and Pharmacodynamic Properties 196
Assessment of surface water quality using multivariate analysis: Case study of the crati River, Italy 195
Antihypertensive effects of novel Quercetin derivatives 194
Lipid lowering and antiglycaemic properties of Tacle® by in vitro and in vivo investigation 192
Quercetin derivatives as novel antihypertensive agents: Synthesis and physiological characterization 191
Homoisoflavones as ligands of estrogen receptors: novel tools for hormone sensitive cancer treatment 191
Photo and thermal stress of linseed oil and stabilization strategies 189
CCR5/CXCR4 dual antagonism for the improvement of HIV infection therapy 187
A new generation of dihydropyridine calcium channel blockers: Photostabilization of liquid formulations using nonionic surfactants 187
STUDI ACCELERATI DI FOTOSTABILITÀ DEI FARMACI. 185
Combination effects of SC144 and cytotoxic anticancer agents 185
Synthesis and biological evaluation of 1,3-Indandione derivatives as acetylcholinesterase inhibitors 184
"Gel formulation of Nabumetone and a newly synthesized analog: Microemulsion as a photoprotective topical delivery system" in PHARMACEUTICS AND ADVANCED DRUG DELIVERY SYSTEMS 182
Benzothienoquinazolinones as new inhibitor of Topoisomerases and Tubulin 180
Benzopyrroloxazines containing a bridgehead nitrogen atom as promising scaffolds for the achievement of biologically active agents 179
Quercetin and its derivative Q2 modulate chromatin dynamics in adipogenesis and Q2 prevents obesity and metabolic disorders in rats 179
Discovery of potential pancreatic lipase inhibitors from Salvia miltiorrhiza Bunge 178
A challenge in the treatment of neuropathic pain: synthesis of new photostable dihydropyridines 176
A critical study on the application of the zero-crossing derivative spectrophotometry to the photodegradation monitoring of lacidipine 174
Cateslytin abrogates lipopolysaccharide-induced cardiomyocyte injury by reducing inflammation and oxidative stress through toll like receptor 4 interaction 172
Identification of two benzopyrroloxazines acting as selective GPER antagonists in breast cancer cells and cancer-associated fibroblasts 171
Chloro-1,4-dimethyl-9H-carbazole Derivatives Displaying Anti-HIV Activity 171
An update on small molecules targeting CXCR4 as starting points for the development of anti-cancer therapeutics. 169
Cryptotanshinone and tanshinone IIA from Salvia milthorrhiza Bunge (Danshen) as a new class of potential pancreatic lipase inhibitors 169
Antihypertensive effects of novel quercetin derivatives. 168
Identification of chlorocarbazole derivatives as potential antiviral agents. 168
Identification by molecular docking of homoisoflavones from leopoldia comosa as ligands of estrogen receptors 168
Cyclodextrin matrices as photoprotective systems of anti-inflammatory agents for topical use 168
Molecular docking studies towards exploring potential anti-estrogen activity of two natural homoisoflavones P117 166
New insights for the use of quercetin analogs in cancer treatment 165
Stability indicating method of Nabmetone and congeners in microemulsion by MCR analysis. 165
Ligand-activated PPARγ downregulates CXCR4 gene expression through a novel identified PPAR response element and inhibits breast cancer progression 162
Carbazole derivatives as kinase-targeting inhibitors for cancer treatment 162
Synthesis and anti-tumor activities of a series of novel quinoxalinhydrazides 158
Molecular docking of two homoisoflavones as ligand of estrogen receptors 157
Liquid crystalline microspheres for 5-fluorouracil specific release 154
Antiproliferative effects of new N-alkylamino carbazole derivatives on breast cancer cell lines. 150
Cyclodextrins in topical gel formulation as photoprotective system for Nabumetone 149
Benzodiazepines and Related Substances: Chemistry 149
Titanium Dioxide Nanoparticles: A Risk for Human Health? 148
Effects of nonionic surfactants on water solubilization and photoprotection of new 1,4-dhydropyridine drugs. 147
The G Protein Estrogen Receptor (GPER) is involved in the resistance to the CDK4/6 inhibitor palbociclib in breast cancer 146
Carbazole and simplified derivatives: Novel tools toward β-adrenergic receptors targeting 146
Identification of novel 2-(1 H-indol-1-yl)-benzohydrazides CXCR4 ligands impairing breast cancer growth & motility 145
Combination of hormones and nutrients for the development of hybrid nutraceuticals. 145
Gel formulation of nabumetone and a newly synthesized analog: Microemulsion as a photoprotective topical delivery system 145
Antiproliferative effects of new carbazole derivative on breast cancer cell lines. 144
QUERCETIN DERIVATIVES AS NOVEL ANTICANCER AGENTS 144
The Peptide ERα17p Is a GPER Inverse Agonist that Exerts Antiproliferative Effects in Breast Cancer Cells 140
Naturally occurring homoisoflavonoids as novel tools against breast cancer 139
Small molecule inhibitors of CXCR4 137
The chromogranin A1-373 fragment reveals how a single change in the protein sequence exerts strong cardioregulatory effects by engaging neuropilin-1 137
Identification of two novel benzo[b]pyrrolo[1,2-d][1,4]oxazin-4-one derivatives acting as GPER antagonists 136
DESIGN OF LIGHT-STABLE FORMULATIONS OF NABUMETONE FOR TOPICAL USE: PHOTODEGRADATION STUDIES AND EX VIVO PERMEATION TESTS 136
Reverse transcriptase inhibitors nanosystems designed for drug stability and controlled delivery 135
Polyphenols from citrus tacle® extract endowed with hmgcr inhibitory activity: An antihypercholesterolemia natural remedy 132
Photostability of newly synthesized 1,4 dihydropyridines: MCR modelling and HPLC analysis 129
Titanium dioxide nanoparticles: metabolic profiling on human keratinocytes 129
p53: una questione di vita o di morte. Una proteina chiave in oncologia 129
TiO2-NPs Toxicity and Safety: An Update of the Findings Published over the Last Six Years 128
Small molecule inhibitors of Stat3 signaling pathway 128
Discovery of Novel Anticancer Compounds Based on Quinoxalinhydrazide Pharmacophore 128
Leptin Signaling Contributes to Aromatase Inhibitor Resistant Breast Cancer Cell Growth and Activation of Macrophages 128
Stabilization of MDA-7/IL-24 for colon cancer therapy 127
Chapter 15 Outdoor Air Pollutants 125
Use of Pluronic Surfactants in Gel Formulations of Photosensitive 1,4-Dihydropyridine Derivatives: A Potential Approach in the Treatment of Neuropathic Pain 125
Cytotoxic potential of novel 6,7-dimethoxyquinazolines 124
Convenient synthesis of fluorazone derivatives by one-pot pyrrolation/cyclization of anthranilic acids 121
Design, Synthesis and Biological Evaluation of Naphthoxazepine Inhibitors of HIV-1-Integrase 120
Small-Molecule Inhibitors of p53-MDM2 Interaction: the 2006-2010 Update 119
Stabilization strategies for photosensitive drugs 119
Design and Synthesis of 3-Carbamoylbenzoic Derivatives as Inhibitors of Human Apurinic/Apyrimidinic Endonuclease 1 (APE1) 119
Quercetin Derivatives: evaluation of anti-proliferative activity and inhibition of human Topoisomerases I and II 118
Valutazione della tossicità acuta di piante medicinali mediante microtox test. 116
Hydrazide-based inhibitors of HDAC enzymes as novel anticancer drugs 116
Design, synthesis and biological evaluation of 7-substituted 4-phenyl-6H-imidazo[1,5-a]thieno[3,2-f] [1,4]diazepines as safe anxiolytic agents 115
Recent Advances in the Design and Discovery of Small-molecule Therapeutics Targeting HER2/neu 114
Estetrol/GPER/SERPINB2 transduction signaling inhibits the motility of triple-negative breast cancer cells 113
DERIVATI DELLA QUERCETINA AD ELEVATA STABILITÀ NELLA PREVENZIONE DELLO STRESS OSSIDATIVO 113
SINTESI DI ANALOGHI STRUTTURALI DEL NABUMETONE PER USO TOPICO: STUDI DI FOTODEGRADAZIONE E DESIGN DI FORMULAZIONI FOTOSTABILI 112
Small molecules anti-HIV therapeutics targeting CXCR4 111
Synthesis and biological evaluation of novel hydrazide based cytotoxic agents 111
Development of PARP-1 inhibitors as novel anticancer drugs 111
Direct cyclization of ortho-(1H-pyrrol-1-yl)aryl and heteroaryl carboxylic acids into fused pyrrolizinones 111
Dissecting CYP1A2 Activation by Arylalkanoic Acid Prodrugs toward the Development of Anti-Inflammatory Agents 110
Interaction of letrozole and its degradation products with aromatase: chemometric assessment of kinetics and structure-based binding validation 110
Composition and Methods For Treating Colon and Ovarian Cancer. 110
Study of the Photodegradation Kinetics of Multicomponent Drug Formulations via MCR-ALS: The Case of the Amiloride-hydrochlorothiazide Mixture 110
Synthesis and photodegradation studies of analogues of muscle relaxant 1,4-dihydropyridine compounds 109
Multivariate curve resolution for the simultaneous kinetic analysis of multicomponent photolabile drug formulations 109
Totale 15.483
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Categoria #
all - tutte 111.859
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 111.859
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.430 0 0 34 95 195 61 28 343 23 9 221 421
2022/20231.989 283 242 93 237 216 165 10 223 208 54 146 112
2023/20241.495 150 56 97 83 99 366 68 66 111 63 76 260
2024/20253.021 197 393 113 176 232 159 120 170 511 222 296 432
2025/20269.547 1.044 397 1.117 668 1.601 747 1.070 513 649 679 504 558
2026/2027876 577 230 69 0 0 0 0 0 0 0 0 0
Totale 21.506