GRANDE, Fedora
 Distribuzione geografica
Continente #
NA - Nord America 6.097
AS - Asia 4.698
EU - Europa 3.459
SA - Sud America 1.144
AF - Africa 303
OC - Oceania 18
Continente sconosciuto - Info sul continente non disponibili 12
AN - Antartide 1
Totale 15.732
Nazione #
US - Stati Uniti d'America 5.861
SG - Singapore 2.234
CN - Cina 991
UA - Ucraina 962
BR - Brasile 870
IT - Italia 724
DE - Germania 684
VN - Vietnam 523
AT - Austria 274
SE - Svezia 264
TR - Turchia 154
KR - Corea 152
SN - Senegal 152
CA - Canada 150
FI - Finlandia 132
IN - India 125
AR - Argentina 116
HK - Hong Kong 99
FR - Francia 81
GB - Regno Unito 70
IQ - Iraq 65
ID - Indonesia 57
BD - Bangladesh 56
ZA - Sudafrica 55
MX - Messico 54
RU - Federazione Russa 49
EC - Ecuador 42
JP - Giappone 39
PK - Pakistan 38
BE - Belgio 34
PL - Polonia 33
ES - Italia 30
NL - Olanda 30
EG - Egitto 29
CO - Colombia 28
VE - Venezuela 26
UZ - Uzbekistan 21
PY - Paraguay 20
SA - Arabia Saudita 18
IE - Irlanda 17
MA - Marocco 17
AU - Australia 16
AE - Emirati Arabi Uniti 15
CL - Cile 13
EU - Europa 12
PE - Perù 12
AZ - Azerbaigian 11
DO - Repubblica Dominicana 11
CZ - Repubblica Ceca 10
KE - Kenya 10
NP - Nepal 10
TN - Tunisia 10
DZ - Algeria 9
LT - Lituania 9
AL - Albania 8
OM - Oman 7
UY - Uruguay 7
BG - Bulgaria 6
BO - Bolivia 6
KG - Kirghizistan 6
TW - Taiwan 6
AM - Armenia 5
GR - Grecia 5
IL - Israele 5
IR - Iran 5
JO - Giordania 5
KZ - Kazakistan 5
LB - Libano 5
LV - Lettonia 5
PS - Palestinian Territory 5
RO - Romania 5
BY - Bielorussia 4
CI - Costa d'Avorio 4
LK - Sri Lanka 4
MY - Malesia 4
NG - Nigeria 4
PA - Panama 4
PT - Portogallo 4
SY - Repubblica araba siriana 4
TH - Thailandia 4
BA - Bosnia-Erzegovina 3
BN - Brunei Darussalam 3
EE - Estonia 3
GE - Georgia 3
GY - Guiana 3
JM - Giamaica 3
PH - Filippine 3
QA - Qatar 3
AO - Angola 2
CR - Costa Rica 2
GA - Gabon 2
HN - Honduras 2
HR - Croazia 2
KW - Kuwait 2
MD - Moldavia 2
NI - Nicaragua 2
NO - Norvegia 2
SV - El Salvador 2
TG - Togo 2
TT - Trinidad e Tobago 2
Totale 15.704
Città #
Singapore 813
Chandler 757
Dallas 723
Jacksonville 550
Boardman 393
Ashburn 329
Dearborn 313
San Mateo 303
Beijing 302
New York 216
Ho Chi Minh City 206
Vienna 200
Rende 160
Dakar 152
Lawrence 140
Roxbury 139
Seoul 134
Hanoi 128
Shanghai 122
Hefei 112
Izmir 97
Hong Kong 96
Munich 95
Brooklyn 94
Helsinki 93
Des Moines 92
Ann Arbor 90
Ottawa 84
Los Angeles 82
Cambridge 66
São Paulo 65
Florence 62
Ogden 49
Wilmington 47
Bremen 45
Grafing 45
Toronto 42
The Dalles 41
Council Bluffs 40
Pune 38
Baghdad 35
Haiphong 34
Inglewood 34
Turku 34
Brussels 33
Columbus 33
Tokyo 33
Rio de Janeiro 31
Cosenza 30
San Francisco 29
Guangzhou 27
Santa Clara 26
Rome 24
Warsaw 24
Redwood City 23
Da Nang 22
Johannesburg 22
Tashkent 20
Chicago 19
Seattle 19
Dublin 17
Catanzaro 16
Faisalabad 16
Jakarta 16
Mexico City 16
Ankara 15
Belo Horizonte 15
Cairo 15
Norwalk 15
Quito 15
Chennai 14
Curitiba 14
Tianjin 14
Bari 13
Boston 13
Düsseldorf 13
Frankfurt am Main 13
Salvador 13
Milan 12
Naples 12
Ninh Bình 12
Stockholm 12
Brasília 11
Buenos Aires 11
Dhaka 11
Guarulhos 11
Istanbul 11
London 11
Scarnafigi 11
Baku 10
Brescia 10
Catania 10
Guayaquil 10
Atlanta 9
Berlin 9
Cape Town 9
Castelnuovo Don Bosco 9
Goiânia 9
Hangzhou 9
Kocaeli 9
Totale 8.598
Nome #
Exploring by-products as sources of bioactive compounds: LC-ESI-QTOF-MS profiling and bioactivity assessment of blood twig dogwood and cornelian cherry leaf extracts and fractions 253
AHR and GPER mediate the stimulatory effects induced by 3-methylcholanthrene in breast cancer cells and cancer-associated fibroblasts (CAFs) 188
A critical study on the zero-crossing method in derivative spectrophotometry 177
A pilot study on the nutraceutical properties of the Citrus hybrid Tacle® as a dietary source of polyphenols for supplementation in metabolic disorders 176
Computational Approaches for the Discovery of GPER Targeting Compounds 173
Antihypertensive effects of novel Quercetin derivatives 168
Assessment of surface water quality using multivariate analysis: Case study of the crati River, Italy 163
Lipid lowering and antiglycaemic properties of Tacle® by in vitro and in vivo investigation 162
Antihypertensive effects of novel Quercetin derivatives 161
An approach to the stereo-controlled synthesis of polycyclic derivatives of L-4-thiazolidinecarboxylic acid active against HIV-1 integrase 160
Benzothienoquinazolinones as new multi-target scaffolds: Dual inhibition of human Topoisomerase I and tubulin polymerization 160
Acute and synergistic toxicity of drugs in water by luminescent bacteria assay 160
Benzothienoquinazolinones as new inhibitor of Topoisomerases and Tubulin 154
"Gel formulation of Nabumetone and a newly synthesized analog: Microemulsion as a photoprotective topical delivery system" in PHARMACEUTICS AND ADVANCED DRUG DELIVERY SYSTEMS 151
Discovery of potential pancreatic lipase inhibitors from Salvia miltiorrhiza Bunge 150
CCR5/CXCR4 dual antagonism for the improvement of HIV infection therapy 149
Photo and thermal stress of linseed oil and stabilization strategies 147
Identification by molecular docking of homoisoflavones from leopoldia comosa as ligands of estrogen receptors 145
Stability indicating method of Nabmetone and congeners in microemulsion by MCR analysis. 143
A challenge in the treatment of neuropathic pain: synthesis of new photostable dihydropyridines 142
Cateslytin abrogates lipopolysaccharide-induced cardiomyocyte injury by reducing inflammation and oxidative stress through toll like receptor 4 interaction 142
Quercetin derivatives as novel antihypertensive agents: Synthesis and physiological characterization 141
Molecular docking studies towards exploring potential anti-estrogen activity of two natural homoisoflavones P117 141
Identification of chlorocarbazole derivatives as potential antiviral agents. 140
An update on small molecules targeting CXCR4 as starting points for the development of anti-cancer therapeutics. 140
Quercetin and its derivative Q2 modulate chromatin dynamics in adipogenesis and Q2 prevents obesity and metabolic disorders in rats 140
Cryptotanshinone and tanshinone IIA from Salvia milthorrhiza Bunge (Danshen) as a new class of potential pancreatic lipase inhibitors 140
STUDI ACCELERATI DI FOTOSTABILITÀ DEI FARMACI. 139
Cyclodextrin matrices as photoprotective systems of anti-inflammatory agents for topical use 139
A new generation of dihydropyridine calcium channel blockers: Photostabilization of liquid formulations using nonionic surfactants 137
Active manganese dioxide promoted cyclization of ortho-(1H-pyrrol- 1-yl)aryl and heteroaryl carboxylic acids to 5H-pyrrolo[1,2-a][3,1] benzoxazin-5-one derivatives 136
Carbazole derivatives as kinase-targeting inhibitors for cancer treatment 136
Synthesis and biological evaluation of 1,3-Indandione derivatives as acetylcholinesterase inhibitors 134
Antihypertensive effects of novel quercetin derivatives. 134
New insights for the use of quercetin analogs in cancer treatment 133
A critical study on the application of the zero-crossing derivative spectrophotometry to the photodegradation monitoring of lacidipine 132
Identification of two benzopyrroloxazines acting as selective GPER antagonists in breast cancer cells and cancer-associated fibroblasts 129
Molecular docking of two homoisoflavones as ligand of estrogen receptors 129
Effects of nonionic surfactants on water solubilization and photoprotection of new 1,4-dhydropyridine drugs. 127
Homoisoflavones as ligands of estrogen receptors: novel tools for hormone sensitive cancer treatment 126
Chloro-1,4-dimethyl-9H-carbazole Derivatives Displaying Anti-HIV Activity 120
Benzopyrroloxazines containing a bridgehead nitrogen atom as promising scaffolds for the achievement of biologically active agents 120
Combination effects of SC144 and cytotoxic anticancer agents 120
Liquid crystalline microspheres for 5-fluorouracil specific release 119
Cyclodextrins in topical gel formulation as photoprotective system for Nabumetone 119
Combination of hormones and nutrients for the development of hybrid nutraceuticals. 117
QUERCETIN DERIVATIVES AS NOVEL ANTICANCER AGENTS 117
The chromogranin A1-373 fragment reveals how a single change in the protein sequence exerts strong cardioregulatory effects by engaging neuropilin-1 116
Antiproliferative effects of new N-alkylamino carbazole derivatives on breast cancer cell lines. 116
Synthesis and anti-tumor activities of a series of novel quinoxalinhydrazides 114
Naturally occurring homoisoflavonoids as novel tools against breast cancer 114
Ligand-activated PPARγ downregulates CXCR4 gene expression through a novel identified PPAR response element and inhibits breast cancer progression 113
Gel formulation of nabumetone and a newly synthesized analog: Microemulsion as a photoprotective topical delivery system 113
Titanium Dioxide Nanoparticles: A Risk for Human Health? 112
Identification of two novel benzo[b]pyrrolo[1,2-d][1,4]oxazin-4-one derivatives acting as GPER antagonists 112
Identification of novel 2-(1 H-indol-1-yl)-benzohydrazides CXCR4 ligands impairing breast cancer growth & motility 111
p53: una questione di vita o di morte. Una proteina chiave in oncologia 111
Benzodiazepines and Related Substances: Chemistry 109
The Peptide ERα17p Is a GPER Inverse Agonist that Exerts Antiproliferative Effects in Breast Cancer Cells 108
Polyphenols from citrus tacle® extract endowed with hmgcr inhibitory activity: An antihypercholesterolemia natural remedy 107
Leptin Signaling Contributes to Aromatase Inhibitor Resistant Breast Cancer Cell Growth and Activation of Macrophages 106
Carbazole and simplified derivatives: Novel tools toward β-adrenergic receptors targeting 106
Anticancer Drugs: Recent Strategies to Improve Stability Profile, Pharmacokinetic and Pharmacodynamic Properties 105
Chapter 15 Outdoor Air Pollutants 105
Antiproliferative effects of new carbazole derivative on breast cancer cell lines. 104
Reverse transcriptase inhibitors nanosystems designed for drug stability and controlled delivery 103
The G Protein Estrogen Receptor (GPER) is involved in the resistance to the CDK4/6 inhibitor palbociclib in breast cancer 99
Small-Molecule Inhibitors of p53-MDM2 Interaction: the 2006-2010 Update 99
Small molecule inhibitors of CXCR4 99
Titanium dioxide nanoparticles: metabolic profiling on human keratinocytes 99
Photostability of newly synthesized 1,4 dihydropyridines: MCR modelling and HPLC analysis 97
Quercetin Derivatives: evaluation of anti-proliferative activity and inhibition of human Topoisomerases I and II 95
Design, synthesis and biological evaluation of 7-substituted 4-phenyl-6H-imidazo[1,5-a]thieno[3,2-f] [1,4]diazepines as safe anxiolytic agents 94
Small molecule inhibitors of Stat3 signaling pathway 93
Synthesis and photodegradation studies of analogues of muscle relaxant 1,4-dihydropyridine compounds 93
DESIGN OF LIGHT-STABLE FORMULATIONS OF NABUMETONE FOR TOPICAL USE: PHOTODEGRADATION STUDIES AND EX VIVO PERMEATION TESTS 93
Study of the Photodegradation Kinetics of Multicomponent Drug Formulations via MCR-ALS: The Case of the Amiloride-hydrochlorothiazide Mixture 93
Cytotoxic potential of novel 6,7-dimethoxyquinazolines 91
DERIVATI DELLA QUERCETINA AD ELEVATA STABILITÀ NELLA PREVENZIONE DELLO STRESS OSSIDATIVO 91
Design, Synthesis and Biological Evaluation of Naphthoxazepine Inhibitors of HIV-1-Integrase 90
Small molecules anti-HIV therapeutics targeting CXCR4 88
Development of PARP-1 inhibitors as novel anticancer drugs 88
Convenient synthesis of fluorazone derivatives by one-pot pyrrolation/cyclization of anthranilic acids 88
SINTESI DI ANALOGHI STRUTTURALI DEL NABUMETONE PER USO TOPICO: STUDI DI FOTODEGRADAZIONE E DESIGN DI FORMULAZIONI FOTOSTABILI 87
Composition and Methods For Treating Colon and Ovarian Cancer. 87
Design and Synthesis of 3-Carbamoylbenzoic Derivatives as Inhibitors of Human Apurinic/Apyrimidinic Endonuclease 1 (APE1) 87
Multivariate curve resolution for the simultaneous kinetic analysis of multicomponent photolabile drug formulations 87
Use of Pluronic Surfactants in Gel Formulations of Photosensitive 1,4-Dihydropyridine Derivatives: A Potential Approach in the Treatment of Neuropathic Pain 86
Photostability study of multicomponent drug formulations via MCR-ALS: The case of the hydrochlorothiazide-amiloride mixture 85
sviluppo di derivati del fluorazone ad attività antitumorale 84
Efficient synthesis of 9H-pyrrolo[1,2-a]indol-9-one derivatives based on active manganese dioxide promoted intramolecular cyclization 83
Synthesis and biological evaluation of novel hydrazide based cytotoxic agents 81
Discovery of Novel Anticancer Compounds Based on Quinoxalinhydrazide Pharmacophore 81
Recent Developments in Pharmaceutical Analysis 2021-RDPA 2021 81
Rutin is a low micromolar inhibitor of sars-cov-2 main protease 3clpro: Implications for drug design of quercetin analogs 81
Valutazione della tossicità acuta di piante medicinali mediante microtox test. 80
Stabilization of MDA-7/IL-24 for colon cancer therapy 80
Dissecting CYP1A2 Activation by Arylalkanoic Acid Prodrugs toward the Development of Anti-Inflammatory Agents 79
Hydrazide-based inhibitors of HDAC enzymes as novel anticancer drugs 79
Quinoxalinhydrazide Pharmacophore Based identification of Novel Anticancer Compounds 79
Totale 11.911
Categoria #
all - tutte 95.014
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 95.014


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021640 0 0 0 0 0 140 35 165 39 150 18 93
2021/20221.706 28 248 34 95 195 61 28 343 23 9 221 421
2022/20231.989 283 242 93 237 216 165 10 223 208 54 146 112
2023/20241.495 150 56 97 83 99 366 68 66 111 63 76 260
2024/20253.021 197 393 113 176 232 159 120 170 511 222 296 432
2025/20264.994 1.044 397 1.117 668 1.601 167 0 0 0 0 0 0
Totale 16.077