IRIS
GRANDE, Fedora
 Distribuzione geografica
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Continente #
NA - Nord America 4.543
EU - Europa 2.832
AS - Asia 1.248
AF - Africa 167
SA - Sud America 24
OC - Oceania 15
Continente sconosciuto - Info sul continente non disponibili 12
Totale 8.841
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Nazione #
US - Stati Uniti d'America 4.420
UA - Ucraina 931
IT - Italia 586
DE - Germania 539
SG - Singapore 477
CN - Cina 440
AT - Austria 270
SE - Svezia 252
SN - Senegal 148
TR - Turchia 133
CA - Canada 120
IN - India 70
FI - Finlandia 67
FR - Francia 49
KR - Corea 42
BE - Belgio 31
GB - Regno Unito 24
HK - Hong Kong 21
BR - Brasile 20
AU - Australia 15
EG - Egitto 15
IE - Irlanda 15
PK - Pakistan 15
ES - Italia 13
EU - Europa 12
NL - Olanda 12
IQ - Iraq 11
JP - Giappone 8
CZ - Repubblica Ceca 7
PL - Polonia 7
SA - Arabia Saudita 7
RU - Federazione Russa 6
GR - Grecia 5
ID - Indonesia 5
LV - Lettonia 4
PT - Portogallo 3
RO - Romania 3
TH - Thailandia 3
UZ - Uzbekistan 3
AM - Armenia 2
AR - Argentina 2
IL - Israele 2
LK - Sri Lanka 2
LT - Lituania 2
MX - Messico 2
NG - Nigeria 2
TW - Taiwan 2
AZ - Azerbaigian 1
BA - Bosnia-Erzegovina 1
CO - Colombia 1
DK - Danimarca 1
EE - Estonia 1
FK - Isole Falkland (Malvinas) 1
KG - Kirghizistan 1
KH - Cambogia 1
MK - Macedonia 1
MY - Malesia 1
PA - Panama 1
SI - Slovenia 1
SK - Slovacchia (Repubblica Slovacca) 1
TN - Tunisia 1
VN - Vietnam 1
ZA - Sudafrica 1
Totale 8.841
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Città #
Chandler 757
Jacksonville 549
Boardman 393
Singapore 353
Dearborn 313
San Mateo 303
New York 196
Vienna 196
Ashburn 167
Dakar 148
Lawrence 140
Roxbury 139
Rende 131
Shanghai 114
Izmir 97
Des Moines 92
Ann Arbor 90
Ottawa 82
Brooklyn 80
Beijing 69
Cambridge 66
Helsinki 63
Florence 59
Ogden 49
Wilmington 47
Los Angeles 46
Bremen 45
Grafing 45
Pune 36
Inglewood 34
Toronto 33
Brussels 30
Cosenza 26
Guangzhou 24
Seoul 24
Redwood City 23
Hong Kong 20
San Francisco 19
Dublin 15
Norwalk 15
Rome 15
Seattle 15
Faisalabad 13
Scarnafigi 11
Baghdad 10
Catania 10
Munich 10
Cairo 9
Castelnuovo Don Bosco 9
Kocaeli 9
Torino 9
Hangzhou 8
Marigliano 8
Nanjing 8
Olgiate Olona 8
Wuhan 8
Haikou 7
Istanbul 7
Lamezia Terme 7
Paris 7
Pulsano 7
Ankara 6
Bari 6
Brno 6
Falls Church 6
Jiaxing 6
Jinhua 6
Madrid 6
Reggio Calabria 6
Washington 6
Canberra 5
Hebei 5
Melbourne 5
Montesano Sulla Marcellana 5
St Petersburg 5
São Paulo 5
Vadodara 5
Villapiana 5
Wuxi 5
Berlin 4
Bydgoszcz 4
Carapelle 4
Chongqing 4
Crotone 4
Milan 4
Monferrato 4
Riga 4
Riyadh 4
Sassari 4
Sydney 4
Amsterdam 3
Asti 3
Buffalo 3
Chicago 3
Clifton 3
Cropani 3
Esslingen am Neckar 3
Fidenza 3
Guangdong 3
Gunzenhausen 3
Totale 5.496
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Nome #
Lipid lowering and antiglycaemic properties of Tacle® by in vitro and in vivo investigation 124
Benzothienoquinazolinones as new multi-target scaffolds: Dual inhibition of human Topoisomerase I and tubulin polymerization 113
Antihypertensive effects of novel Quercetin derivatives 111
AHR and GPER mediate the stimulatory effects induced by 3-methylcholanthrene in breast cancer cells and cancer-associated fibroblasts (CAFs) 111
A pilot study on the nutraceutical properties of the Citrus hybrid Tacle® as a dietary source of polyphenols for supplementation in metabolic disorders 106
Benzothienoquinazolinones as new inhibitor of Topoisomerases and Tubulin 106
A critical study on the zero-crossing method in derivative spectrophotometry 105
Computational Approaches for the Discovery of GPER Targeting Compounds 105
Identification of chlorocarbazole derivatives as potential antiviral agents. 103
Discovery of potential pancreatic lipase inhibitors from Salvia miltiorrhiza Bunge 103
Photo and thermal stress of linseed oil and stabilization strategies 102
"Gel formulation of Nabumetone and a newly synthesized analog: Microemulsion as a photoprotective topical delivery system" in PHARMACEUTICS AND ADVANCED DRUG DELIVERY SYSTEMS 101
Carbazole derivatives as kinase-targeting inhibitors for cancer treatment 100
Effects of nonionic surfactants on water solubilization and photoprotection of new 1,4-dhydropyridine drugs. 97
Stability indicating method of Nabmetone and congeners in microemulsion by MCR analysis. 97
Acute and synergistic toxicity of drugs in water by luminescent bacteria assay 96
Assessment of surface water quality using multivariate analysis: Case study of the crati River, Italy 96
Identification by molecular docking of homoisoflavones from leopoldia comosa as ligands of estrogen receptors 95
Antihypertensive effects of novel Quercetin derivatives 95
Cyclodextrin matrices as photoprotective systems of anti-inflammatory agents for topical use 95
An approach to the stereo-controlled synthesis of polycyclic derivatives of L-4-thiazolidinecarboxylic acid active against HIV-1 integrase 93
Molecular docking studies towards exploring potential anti-estrogen activity of two natural homoisoflavones P117 93
New insights for the use of quercetin analogs in cancer treatment 92
CCR5/CXCR4 dual antagonism for the improvement of HIV infection therapy 92
Molecular docking of two homoisoflavones as ligand of estrogen receptors 90
Quercetin and its derivative Q2 modulate chromatin dynamics in adipogenesis and Q2 prevents obesity and metabolic disorders in rats 89
Quercetin derivatives as novel antihypertensive agents: Synthesis and physiological characterization 88
Active manganese dioxide promoted cyclization of ortho-(1H-pyrrol- 1-yl)aryl and heteroaryl carboxylic acids to 5H-pyrrolo[1,2-a][3,1] benzoxazin-5-one derivatives 88
Identification of two benzopyrroloxazines acting as selective GPER antagonists in breast cancer cells and cancer-associated fibroblasts 85
Liquid crystalline microspheres for 5-fluorouracil specific release 84
Synthesis and biological evaluation of 1,3-Indandione derivatives as acetylcholinesterase inhibitors 83
A challenge in the treatment of neuropathic pain: synthesis of new photostable dihydropyridines 83
p53: una questione di vita o di morte. Una proteina chiave in oncologia 82
Cryptotanshinone and tanshinone IIA from Salvia milthorrhiza Bunge (Danshen) as a new class of potential pancreatic lipase inhibitors 81
An update on small molecules targeting CXCR4 as starting points for the development of anti-cancer therapeutics. 79
A new generation of dihydropyridine calcium channel blockers: Photostabilization of liquid formulations using nonionic surfactants 79
Cateslytin abrogates lipopolysaccharide-induced cardiomyocyte injury by reducing inflammation and oxidative stress through toll like receptor 4 interaction 79
A critical study on the application of the zero-crossing derivative spectrophotometry to the photodegradation monitoring of lacidipine 78
QUERCETIN DERIVATIVES AS NOVEL ANTICANCER AGENTS 77
Titanium Dioxide Nanoparticles: A Risk for Human Health? 76
Antihypertensive effects of novel quercetin derivatives. 75
Identification of novel 2-(1 H-indol-1-yl)-benzohydrazides CXCR4 ligands impairing breast cancer growth & motility 73
Chapter 15 Outdoor Air Pollutants 73
The chromogranin A1-373 fragment reveals how a single change in the protein sequence exerts strong cardioregulatory effects by engaging neuropilin-1 73
STUDI ACCELERATI DI FOTOSTABILITÀ DEI FARMACI. 72
Chloro-1,4-dimethyl-9H-carbazole Derivatives Displaying Anti-HIV Activity 72
Homoisoflavones as ligands of estrogen receptors: novel tools for hormone sensitive cancer treatment 71
Naturally occurring homoisoflavonoids as novel tools against breast cancer 71
Ligand-activated PPARγ downregulates CXCR4 gene expression through a novel identified PPAR response element and inhibits breast cancer progression 69
Benzopyrroloxazines containing a bridgehead nitrogen atom as promising scaffolds for the achievement of biologically active agents 69
Antiproliferative effects of new N-alkylamino carbazole derivatives on breast cancer cell lines. 69
The Peptide ERα17p Is a GPER Inverse Agonist that Exerts Antiproliferative Effects in Breast Cancer Cells 68
Combination effects of SC144 and cytotoxic anticancer agents 67
Composition and Methods For Treating Colon and Ovarian Cancer. 66
Polyphenols from citrus tacle® extract endowed with hmgcr inhibitory activity: An antihypercholesterolemia natural remedy 66
Cytotoxic potential of novel 6,7-dimethoxyquinazolines 65
Convenient synthesis of fluorazone derivatives by one-pot pyrrolation/cyclization of anthranilic acids 65
Cyclodextrins in topical gel formulation as photoprotective system for Nabumetone 65
Antiproliferative effects of new carbazole derivative on breast cancer cell lines. 64
DESIGN OF LIGHT-STABLE FORMULATIONS OF NABUMETONE FOR TOPICAL USE: PHOTODEGRADATION STUDIES AND EX VIVO PERMEATION TESTS 64
Study of the Photodegradation Kinetics of Multicomponent Drug Formulations via MCR-ALS: The Case of the Amiloride-hydrochlorothiazide Mixture 64
Carbazole and simplified derivatives: Novel tools toward β-adrenergic receptors targeting 64
Small molecule inhibitors of Stat3 signaling pathway 63
Titanium dioxide nanoparticles: metabolic profiling on human keratinocytes 63
Leptin Signaling Contributes to Aromatase Inhibitor Resistant Breast Cancer Cell Growth and Activation of Macrophages 63
Multivariate curve resolution for the simultaneous kinetic analysis of multicomponent photolabile drug formulations 62
Synthesis and anti-tumor activities of a series of novel quinoxalinhydrazides 61
Gel formulation of nabumetone and a newly synthesized analog: Microemulsion as a photoprotective topical delivery system 61
Small-Molecule Inhibitors of p53-MDM2 Interaction: the 2006-2010 Update 60
Design, Synthesis and Biological Evaluation of Naphthoxazepine Inhibitors of HIV-1-Integrase 60
Benzodiazepines and Related Substances: Chemistry 60
Identification of two novel benzo[b]pyrrolo[1,2-d][1,4]oxazin-4-one derivatives acting as GPER antagonists 58
Recent Developments in Pharmaceutical Analysis 2021-RDPA 2021 58
Small molecule inhibitors of CXCR4 57
Quercetin Derivatives: evaluation of anti-proliferative activity and inhibition of human Topoisomerases I and II 57
SINTESI DI ANALOGHI STRUTTURALI DEL NABUMETONE PER USO TOPICO: STUDI DI FOTODEGRADAZIONE E DESIGN DI FORMULAZIONI FOTOSTABILI 56
Reverse transcriptase inhibitors nanosystems designed for drug stability and controlled delivery 56
Combination of hormones and nutrients for the development of hybrid nutraceuticals. 55
DERIVATI DELLA QUERCETINA AD ELEVATA STABILITÀ NELLA PREVENZIONE DELLO STRESS OSSIDATIVO 54
Naphthoxazepine Inhibitors of HIV-1 Integrase: Synthesis and Biological Evaluation 53
Small molecules anti-HIV therapeutics targeting CXCR4 52
Design and Synthesis of 3-Carbamoylbenzoic Derivatives as Inhibitors of Human Apurinic/Apyrimidinic Endonuclease 1 (APE1) 52
Virtual screening in drug discovery: a precious tool for a still-demanding challenge 52
Valutazione della tossicità acuta di piante medicinali mediante microtox test. 51
Design, synthesis and biological evaluation of 7-substituted 4-phenyl-6H-imidazo[1,5-a]thieno[3,2-f] [1,4]diazepines as safe anxiolytic agents 51
Synthesis and photodegradation studies of analogues of muscle relaxant 1,4-dihydropyridine compounds 50
Synthesis of nabumetone analogues for topical use: photodegradation studies and design of light-stable formulations 50
Efficient synthesis of 9H-pyrrolo[1,2-a]indol-9-one derivatives based on active manganese dioxide promoted intramolecular cyclization 49
Rutin is a low micromolar inhibitor of sars-cov-2 main protease 3clpro: Implications for drug design of quercetin analogs 49
Direct cyclization of ortho-(1H-pyrrol-1-yl)aryl and heteroaryl carboxylic acids into fused pyrrolizinones 48
Photostability study of multicomponent drug formulations via MCR-ALS: The case of the hydrochlorothiazide-amiloride mixture 48
Synthesis and biological evaluation of novel hydrazide based cytotoxic agents 47
Recent Advances in the Design and Discovery of Small-molecule Therapeutics Targeting HER2/neu 46
Discovery and preclinical evaluation of a pyrroloquinoxaline based broad-spectrum anticancer agent 46
SYNTHESIS AND BIOLOGICAL EVALUATION OF 3-CARBAMOYLBENZOIC DERIVATIVES AS INHIBITORS OF HUMAN APURINIC/APYRIMIDINICENDONUCLEASE 1 (APE1) 46
Stabilization strategies for photosensitive drugs 46
Hydrazide-based inhibitors of HDAC enzymes as novel anticancer drugs 46
Discovery of Novel Anticancer Compounds Based on Quinoxalinhydrazide Pharmacophore 46
Stabilization of MDA-7/IL-24 for colon cancer therapy 46
Design and Synthesis of Pyrroloquinoxaline Based as Anticancer Agents 45
Totale 7.280
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Categoria #
all - tutte 61.509
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 61.509
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020891 0 0 0 0 85 319 87 128 34 38 130 70
2020/20211.103 158 2 122 165 16 140 35 165 39 150 18 93
2021/20221.706 28 248 34 95 195 61 28 343 23 9 221 421
2022/20231.989 283 242 93 237 216 165 10 223 208 54 146 112
2023/20241.495 150 56 97 83 99 366 68 66 111 63 76 260
2024/20251.093 197 393 113 176 214 0 0 0 0 0 0 0
Totale 9.155